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Potential Health Impact of Microplastics: A Review of Environmental Distribution, Human Exposure, and Toxic Effects
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This review summarizes existing research on how microplastics are found throughout the environment and in human samples, entering the body through food, air, and skin contact. Lab studies in cells and animals show microplastics can cause oxidative stress, DNA damage, immune reactions, brain toxicity, and reproductive harm, and early human health data links microplastic exposure to several chronic diseases.
Microplastics are ubiquitous in the global environment. As a typical emerging pollutant, its potential health hazards have been widely concerning. In this brief paper, we introduce the source, identification, toxicity, and health hazard of microplastics in the human. The literature review shows that microplastics are frequently detected in environmental and human samples. Humans are potentially exposed to microplastics through oral intake, inhalation, and skin contact. We summarize the toxic effects of microplastics in experimental models like cells, organoids, and animals. These effects consist of oxidative stress, DNA damage, organ dysfunction, metabolic disorder, immune response, neurotoxicity, as well as reproductive and developmental toxicity. In addition, the epidemiological evidence suggests that a variety of chronic diseases may be related to microplastics exposure. Finally, we put forward the gaps in toxicity research of microplastics and their future development directions. This review will be helpful to the understanding of the exposure risk and potential health hazards of microplastics.
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This review summarizes what is known about how microplastics and nanoplastics enter the human body through food, air, and skin contact, and what they do once inside. Studies on cells and animals show these tiny particles can cause oxidative stress, DNA damage, inflammation, and harm to the immune, digestive, reproductive, and nervous systems. The research makes clear that microplastics are not just an environmental problem but a direct concern for human health.
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This review examines the potential health effects of human exposure to microplastics through ingestion, inhalation, and skin contact. Researchers found that microplastic exposure may cause oxidative stress, inflammation, and immune system disruption, with the body's inability to break down synthetic particles potentially leading to chronic inflammation. The study emphasizes that while evidence of harm is growing, microplastic toxicity varies greatly depending on particle properties, concentration, and individual susceptibility.
The Impact of Microplastic on Human Health
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This review synthesized evidence on microplastic exposure pathways and health effects in humans, finding that microplastics enter the body via ingestion, inhalation, and dermal contact and are associated with oxidative stress, inflammation, genotoxicity, and endocrine disruption.
Human exposure to microplastics: A review on exposure routes and public health impacts
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This review examines how microplastics enter the human body through food, air, and skin contact and the health effects they can cause, including oxidative stress, inflammation, hormone disruption, and potential DNA damage. Despite growing evidence of harm, the exact routes plastics take through the body and the cellular mechanisms behind their effects are still not well understood, and there is an urgent need for standardized detection methods.
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This review summarizes current evidence on how micro- and nanoplastics enter the human body through food, air, and skin contact, and the cellular damage they may cause. While microplastic pollution is a recognized environmental hazard, the authors note that definitive evidence linking plastic particle exposure to specific health outcomes in humans is still limited and more realistic exposure studies are needed.
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When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.