We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Impacts of micro- and nanoplastic exposure on the cardiovascular system: a systematic review focused on in vivo studies
AI summary Read the abstract
This systematic review summarizes 38 animal studies on how micro- and nanoplastics affect the heart and blood vessels. The research found that these tiny plastic particles can deposit in cardiovascular tissue, trigger inflammation and oxidative stress, and cause structural damage, raising concerns about potential heart health risks from ongoing plastic exposure.
Microplastics and nanoplastics, degraded plastic polymers, are increasing in the environment, raising concerns about their potential health impacts, particularly on the cardiovascular system. This systematic review aimed to investigate the prospective effects of MPs and NPs on cardiovascular toxicity. This study was written following the PRISMA 2020 guidelines. The risk of bias in the included studies was assessed using the SYRCLE tool. Our review included 38 in vivo studies dating back from 2017 to 2024 from several databases, including PubMed, ScienceDirect, SpringerLink, Taylor & Francis, ProQuest, and Wiley Online Library, with inclusion criteria of (PECOS) (1) Population: Animal; (2) Exposure: All types of exposure to micro nanoplastics; (3) Comparison: Placebo/ Control; (4) Outcome: Cardiotoxicity, inhibition of development of cardiovascular tissue, oxidative stress, inflammation, and abnormal structure; and (5) Study design: In vivo experimental study. Studies reveal that MPs and NPs cause cardiovascular toxicity through deposition, morphological changes, biomarker alterations, metabolism changes, and genetic regulation related to injury, inflammation, and oxidative stress. This study is limited to the comparison of the different particle sizes, dose of exposure, and duration of exposure effects toward cardiotoxicity, and does not compare the different effects of toxicity between different particle types.
More Papers Like This
Micro- and nanoplastics in the cardiovascular system: current evidence, research gaps: a systematic review
AI summary Read the abstract
This systematic review examined how microplastics and nanoplastics affect the heart and blood vessels. Studies in both animals and human tissue found that these particles can cause blood vessel inflammation, disrupt heart function, and were even linked to higher rates of heart attack and stroke in people with plastic particles in their arteries.
Micro/nano-plastics impacts in cardiovascular systems across species
AI summary Read the abstract
This review summarizes research across multiple species showing that microplastics and nanoplastics can damage the cardiovascular system, causing blood clots, blood vessel injury, and heart problems in lab animals. Since these tiny particles have been found in human blood and can travel throughout the body, the findings raise serious concerns about the long-term heart health effects of microplastic exposure in people.
From pollution to palpitations: the heart’s silent battle with microplastics
AI summary Read the abstract
This systematic review examined 72 studies on how microplastics and nanoplastics affect the heart and blood vessels. The research found that these particles can impair heart function, cause tissue scarring, and trigger inflammation through oxidative stress. Smaller particles under 100 nanometers are especially concerning because they can penetrate deeper into the body, raising questions about the cardiovascular risks of long-term plastic particle exposure.
Micro- and nanoplastics: A new cardiovascular risk factor?
AI summary Read the abstract
This review examines the growing evidence that micro- and nanoplastics may pose risks to the heart and blood vessels. Studies in animals and cell cultures show that these tiny plastic particles can enter the bloodstream, trigger inflammation, promote blood clotting, and damage blood vessel walls. While human data is still limited, the review suggests that micro- and nanoplastic exposure should be considered a potential new risk factor for cardiovascular disease.
Microplastics, Nanoplastics and Heart Contamination: The Hidden Threat
AI summary Read the abstract
This review examines growing evidence that micro- and nanoplastics can accumulate in human cardiovascular tissues, including blood, heart muscle, and arterial plaques. Researchers found that these particles may contribute to heart and blood vessel problems through inflammation, oxidative stress, blood clotting, and direct tissue injury. The study identifies plastic particles as a potential new environmental risk factor for cardiovascular health.
Research digests by email
When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.