Papers

61,005 results
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Article Tier 2

Genomics and transcriptomics of the green mussel explain the durability of its byssus

Researchers used whole-genome and foot-specific transcriptomic analysis of the green mussel Perna viridis to identify genes responsible for byssus formation, finding that proteinase inhibitors and cross-linking proteins contribute to the exceptional durability and enzymatic resistance of mussel attachment threads.

2021 Scientific Reports 27 citations
Article Tier 2

Profiling of microRNAs and mRNAs in marine mussel Mytilus galloprovincialis

Researchers used deep sequencing to profile microRNAs in the Mediterranean blue mussel Mytilus galloprovincialis, identifying 137 miRNA sequences — 104 conserved across species and 33 potentially novel — providing a genomic baseline for studying how this ecologically important species responds to environmental stressors.

2019 Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology 15 citations
Article Tier 2

De novo assembly of the Carcinus maenas transcriptome and characterization of innate immune system pathways

Researchers assembled a comprehensive genetic transcript library (transcriptome) for the European shore crab (Carcinus maenas), a widely studied species, and identified key genes and pathways involved in its immune system. This genetic resource will help scientists study how crabs respond to environmental stressors, including microplastic exposure.

2015 BMC Genomics 57 citations
Article Tier 2

Revealing the Impact of Polystyrene Nanoplastics on Gill Tissues of the Intertidal Clam, Gafrarium Divaricatum (Gmelin, 1791) using Transcriptomics Approach

Researchers exposed intertidal clams to polystyrene nanoplastics and used transcriptomics to assess gill tissue impacts, finding 1,182 upregulated and 1,626 downregulated genes related to immune modulation, antioxidant defense, and apoptosis. Histopathological examination revealed structural damage to gill tissues including ciliary erosion, lamellae fusion, and lipofuscin accumulation. The study establishes a high-quality genomic resource for this clam species while demonstrating the ecotoxicological effects of nanoplastics on sessile marine bivalves.

2026 Marine Biotechnology
Article Tier 2

Chromosome-Level Genome Assembly of the Blue Mussel Mytilus chilensis Reveals Molecular Signatures Facing the Marine Environment

Scientists assembled the first chromosome-level genome of the Chilean blue mussel, an important aquaculture species in South America. The genome revealed genetic adaptations related to immune defense, stress response, and shell formation that help the mussels survive in challenging marine environments. This genomic resource will support breeding programs and help researchers understand how mussels respond to environmental stressors including pollution.

2023 Genes 25 citations
Article Tier 2

Organ-oriented proteogenomics functional atlas of three aquatic invertebrate sentinel species

Researchers created organ-level proteomic atlases for three aquatic invertebrate sentinel species used in environmental monitoring, identifying thousands of proteins across hepatopancreas, gills, and hemolymph that provide a valuable resource for ecotoxicological studies of pollution impacts.

2023 Scientific Data 5 citations
Article Tier 2

Occurrence and human health risks of microplastics in the Bay of Bengal using Perna viridis as sentinel species

Researchers found microplastics in water, sediment, and green mussel tissues at every site tested across five locations in the Bay of Bengal. The mussels showed tissue damage including inflammation and cell death linked to microplastic accumulation, with the digestive gland carrying the highest burden. Since these mussels are consumed by local communities, the findings raise direct concerns about human microplastic exposure through seafood.

2026 Chemical Engineering Journal Advances 4 citations
Article Tier 2

Transcriptomic analysis reveals interactive effects of polyvinyl chloride microplastics and cadmium on Mytilus galloprovincialis: Insights into non-coding RNA responses and environmental implications

Researchers used whole-transcriptome sequencing to study how mussels respond at the molecular level to combined exposure to PVC microplastics and cadmium. They found that the combined pollutants triggered distinct gene expression patterns, particularly in non-coding RNAs involved in immune and stress responses. The study suggests that microplastics and heavy metals together may cause more complex biological effects than either pollutant alone.

2024 Aquatic Toxicology 4 citations
Article Tier 2

Physiological and transcriptome analysis of Mytilus coruscus in response to Prorocentrum lima and microplastics

The combined effects of diarrhetic shellfish toxin and microplastics on the mussel Mytilus coruscus were assessed at physiological and transcriptomic levels, revealing synergistic disruption of immune function, antioxidant responses, and metabolic pathways. The study provides molecular-level evidence of interactive toxicity between two common coastal contaminants.

2022 Frontiers in Marine Science 18 citations
Article Tier 2

Insights into the molecular response of Dioithona rigida to selenium nanoparticles: de novo transcriptome assembly and differential gene expression analysis

Researchers exposed a marine copepod species to selenium nanoparticles and used genetic analysis to understand the molecular-level effects. They found significant changes in genes related to DNA repair, oxidative stress response, and cell membrane function. The study matters because copepods are a key link in marine food chains, so contaminant effects on these tiny organisms can have ripple effects through the ecosystem and ultimately affect the seafood humans consume.

2024 Science and Technology of Advanced Materials 6 citations
Article Tier 2

Analysis of Pollutant Accumulation in the Invasive Bivalve Perna viridis: Current Status in the Colombian Caribbean 2020–2023

Researchers monitored pollutant levels in the invasive Asian green mussel in Colombia's Caribbean waters over a four-year period, measuring heavy metals alongside environmental factors. Seasonal climate patterns driven by El Nino and La Nina significantly influenced metal accumulation in the mussels. The study demonstrates that invasive bivalves like Perna viridis can serve as useful biomonitors for tracking pollution trends in coastal ecosystems where microplastics and other contaminants coexist.

2025 Toxics 7 citations
Article Tier 2

Hypoxia in the Blue Mussel Mytilus chilensis Induces Transcriptome Shift Associated with Endoplasmic Reticulum Stress, Metabolism, and Immune Response.

Scientists used gene expression analysis to study how low-oxygen conditions affect the blue mussel Mytilus chilensis at the molecular level. Researchers found that hypoxia triggered stress responses in the mussels' gills, digestive glands, and muscles, including cellular stress pathways, metabolic shifts, and immune changes. The study highlights how climate-driven oxygen depletion in coastal waters can stress economically important shellfish species.

2024 Preprints.org 5 citations
Article Tier 2

Single and repetitive microplastics exposures induce immune system modulation and homeostasis alteration in the edible mussel Mytilus galloprovincialis

Researchers examined transcriptome-wide gene expression changes in Mediterranean mussels after single and repeated microplastic exposures, finding significant immune system modulation and disruption of cellular homeostasis. The study suggests that both short-term and chronic microplastic exposure can alter immune regulation pathways in filter-feeding bivalves, with repeated exposures showing cumulative effects.

2018 Fish & Shellfish Immunology 192 citations
Article Tier 2

Insights into the Response in Digestive Gland of Mytilus coruscus under Heat Stress Using TMT-Based Proteomics

Researchers investigated how heat stress affects the digestive gland of thick-shelled mussels using advanced protein analysis techniques. They found significant changes in proteins related to immune defense, energy metabolism, and stress response, revealing the biological mechanisms behind heat-related mussel die-offs. While focused on temperature stress, the study provides foundational knowledge about mussel resilience that is relevant to understanding how environmental stressors, including pollutants, affect these important marine organisms.

2023 Animals 16 citations
Article Tier 2

Copper-Induced Ionoregulatory Disturbance, Histopathology, and Transcriptome Responses in Freshwater Mussel (Anodonta woodiana) Gills

Researchers investigated copper toxicity in the freshwater mussel Anodonta woodiana, finding that sublethal exposure caused ionoregulatory disturbance, gill histopathology, and significant transcriptomic changes related to stress response and immune function.

2023 Fishes 10 citations
Article Tier 2

Standardized trimodal histopathological examination for microplastic detection and tissue-level assessment in green mussels (Perna viridis) cultivated near an industrial estate in Rayong, Thailand

Researchers applied a standardised trimodal histopathological examination to detect microplastics in green mussels (Perna viridis) cultivated near an industrial estate in Rayong, Thailand, finding digestive tracts, gills, and digestive glands to be the most informative tissues for biomonitoring, with plastic presence even in tissues showing no obvious lesions.

2025 Veterinary World
Review Tier 2

The use of green mussel as bioindicator of heavy metal pollution in Indonesia: a review

This review covers the use of Asian green mussel Perna viridis as a bioindicator of heavy metal pollution in Indonesian waters, summarizing studies on metal accumulation in mussel tissue relative to water quality and discussing implications for seafood safety.

2021 Environmental Analysis Health and Toxicology 14 citations
Article Tier 2

Immunological Responses of Marine Bivalves to Contaminant Exposure: Contribution of the -Omics Approach

This review examines how contaminant exposure, including emerging pollutants like microplastics, affects the immune responses of marine bivalves using omics-based approaches. Researchers found that combining transcriptomic, proteomic, and metabolomic data provides a more comprehensive picture of how pollutants disrupt bivalve immunity than traditional single-endpoint studies. The study highlights bivalves as valuable sentinel organisms for monitoring the immunological impacts of marine pollution.

2021 Frontiers in Immunology 75 citations
Article Tier 2

Integrated Metagenomic and Metabolomic Analysis on Two Competing Mussels, Mytella strigata and Perna viridis, in China

Researchers used integrated metagenomic and metabolomic analysis to compare the invasive mussel Mytella strigata with the native Perna viridis in China, finding that the invasive species exhibits distinct gut microbial communities and metabolic profiles that may contribute to its competitive advantage.

2024 Animals 6 citations
Meta Analysis Tier 1

Exploring the Potential of Metatranscriptomics to Describe Microbial Communities and Their Effects in Molluscs

Metatranscriptomics revealed a more complete picture of mussel microbiomes — including bacteria, viruses, fungi, and protozoans — than traditional 16S sequencing alone. The approach also identified host genes whose expression changed with pathogen load, providing new insights into how molluscs respond to microbial infections.

2022 International Journal of Molecular Sciences 11 citations
Article Tier 2

The native mussel Mytilus chilensis genome reveals adaptative molecular signatures facing the marine environment

Researchers sequenced and analyzed the genome of the native Chilean blue mussel Mytilus chilensis, identifying adaptive molecular signatures that reflect the species' responses to diverse marine environmental conditions, with implications for understanding resilience in an aquaculture species reliant on wild seed collection.

2022 2 citations
Review Tier 2

The Next Generation Is Here: A Review of Transcriptomic Approaches in Marine Ecology

This review assessed transcriptomic approaches in marine ecology, highlighting how next-generation sequencing technologies are enabling researchers to address ecological questions including organism responses to environmental stressors at the molecular level.

2022 Frontiers in Marine Science 26 citations
Article Tier 2

Neurophysiological and Immunological Effects of Microplastics in Green Mussels (Perna viridis) from N4 Beach and Pulicat Lake, Tamil Nadu, India

Researchers examined the neurophysiological, immunological, and biochemical effects of environmental microplastic exposure on green mussels (Perna viridis) collected from two coastal sites in Tamil Nadu, India with differing pollution levels. The study found measurable differences in stress biomarkers between sites, suggesting that ambient microplastic contamination levels affect the physiological health of these commercially important filter-feeding bivalves.

2026 UTTAR PRADESH JOURNAL OF ZOOLOGY
Article Tier 2

Size-dependent effects of microplastics on intestinal microbiome for Perna viridis

Researchers found that the size of microplastic particles determines how they change the gut bacteria of green mussels, with the smallest particles causing the most disruption to beneficial bacteria and promoting potentially harmful species. Since mussels are widely consumed as seafood, changes to their gut health and the bacteria they carry could affect human food safety.

2024 Journal of Hazardous Materials 23 citations