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De novo assembly of the Carcinus maenas transcriptome and characterization of innate immune system pathways

BMC Genomics 2015 57 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 35 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Bas Verbruggen, Lisa K. Bickley, Eduarda M. Santos, Charles R. Tyler, Grant D. Stentiford, Kelly S. Bateman, Ronny van Aerle

Summary

Researchers assembled a comprehensive genetic transcript library (transcriptome) for the European shore crab (Carcinus maenas), a widely studied species, and identified key genes and pathways involved in its immune system. This genetic resource will help scientists study how crabs respond to environmental stressors, including microplastic exposure.

We have produced an assembled transcriptome for C. maenas that provides a significant molecular resource for wide ranging studies in this species. Analysis of the transcriptome has revealed the presence of a series of known targets and functional pathways that form part of their innate immune system and illustrate tissue specific differences in their expression patterns.

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