0
Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Human Health Effects Marine & Wildlife Policy & Risk Sign in to save

De novo transcriptome assembly of the Perna viridis: A novel invertebrate model for ecotoxicological studies

Scientific Data 2025 2 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 58 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
V. G. Vysakh, Sandhya Sukumaran, A. Gopalakrishnan

Summary

Researchers created the first detailed gene reference map for the gill tissue of the Asian green mussel, an important species for monitoring ocean pollution. They identified over 47,000 gene sequences, including many related to immune defense and stress responses. This genetic resource will help scientists better understand how marine organisms respond to environmental contaminants like microplastics and heavy metals at the molecular level.

Mussels, particularly Perna viridis, are vital sentinel species for toxicology and biomonitoring in environmental health. This species plays a crucial role in aquaculture and significantly impacts the fisheries sector. Despite the ecological and economic importance of this species, its omics resources are still scarce. We generated a gill-specific reference transcriptome for Perna viridis using 292 million short Illumina reads from eight pooled gill tissue samples isolated from twenty-four individuals. The Trinity assembler generated 438,842 transcripts with an N50 of 1,958 bp. Several databases were employed in the annotation process. This dataset greatly expands the omics resources of bivalve databases and advances our knowledge of transcriptomics, molecular biology, environmental toxicology, and cancer research.

Sign in to start a discussion.

More Papers Like This

Article Tier 2

Genomics and transcriptomics of the green mussel explain the durability of its byssus

Researchers used whole-genome and foot-specific transcriptomic analysis of the green mussel Perna viridis to identify genes responsible for byssus formation, finding that proteinase inhibitors and cross-linking proteins contribute to the exceptional durability and enzymatic resistance of mussel attachment threads.

Article Tier 2

Profiling of microRNAs and mRNAs in marine mussel Mytilus galloprovincialis

Researchers used deep sequencing to profile microRNAs in the Mediterranean blue mussel Mytilus galloprovincialis, identifying 137 miRNA sequences — 104 conserved across species and 33 potentially novel — providing a genomic baseline for studying how this ecologically important species responds to environmental stressors.

Article Tier 2

De novo assembly of the Carcinus maenas transcriptome and characterization of innate immune system pathways

Researchers assembled a comprehensive genetic transcript library (transcriptome) for the European shore crab (Carcinus maenas), a widely studied species, and identified key genes and pathways involved in its immune system. This genetic resource will help scientists study how crabs respond to environmental stressors, including microplastic exposure.

Article Tier 2

Revealing the Impact of Polystyrene Nanoplastics on Gill Tissues of the Intertidal Clam, Gafrarium Divaricatum (Gmelin, 1791) using Transcriptomics Approach

Researchers exposed intertidal clams to polystyrene nanoplastics and used transcriptomics to assess gill tissue impacts, finding 1,182 upregulated and 1,626 downregulated genes related to immune modulation, antioxidant defense, and apoptosis. Histopathological examination revealed structural damage to gill tissues including ciliary erosion, lamellae fusion, and lipofuscin accumulation. The study establishes a high-quality genomic resource for this clam species while demonstrating the ecotoxicological effects of nanoplastics on sessile marine bivalves.

Article Tier 2

Chromosome-Level Genome Assembly of the Blue Mussel Mytilus chilensis Reveals Molecular Signatures Facing the Marine Environment

Scientists assembled the first chromosome-level genome of the Chilean blue mussel, an important aquaculture species in South America. The genome revealed genetic adaptations related to immune defense, stress response, and shell formation that help the mussels survive in challenging marine environments. This genomic resource will support breeding programs and help researchers understand how mussels respond to environmental stressors including pollution.

Share this paper