Papers

61,005 results
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Article Tier 2

Transcriptional response in the whiteleg shrimp (Penaeus vannamei) to short-term microplastic exposure

Researchers exposed whiteleg shrimp (Penaeus vannamei) to microplastics for 96 hours and used transcriptomics to profile gene expression changes, finding significant upregulation of stress response, immune, and detoxification pathways, indicating that even short-term microplastic exposure triggers a broad molecular stress response.

2021 Aquaculture Reports 26 citations
Article Tier 2

The Oryza sativa transcriptome responds spatiotemporally to polystyrene nanoplastic stress

Researchers profiled the full transcriptome of rice roots and leaves at multiple time points during polystyrene nanoplastic exposure, finding that nanoplastics suppress photosynthesis and sugar metabolism while activating plant defense pathways — with effects differing between organs and time points in ways that suggest indirect harm via disruption of plant-microbe interactions.

2024 The Science of The Total Environment 10 citations
Article Tier 2

Microplastics affect rice (Oryza sativa L.) quality by interfering metabolite accumulation and energy expenditure pathways: A field study

Researchers conducted a field study examining how polystyrene microplastics affect rice grain quality at the molecular level using metabolomic and transcriptomic analysis. They found that microplastic exposure interfered with metabolite accumulation and energy pathways in the rice plants, ultimately reducing grain quality. The study provides real-world evidence that microplastic contamination in agricultural soils can directly compromise the nutritional quality of a major food crop.

2021 Journal of Hazardous Materials 193 citations
Article Tier 2

Distinguish the toxic differentiations between acute exposure of micro- and nano-plastics on bivalves: An integrated study based on transcriptomic sequencing

Researchers found that nanoplastics are more toxic than microplastics in mussels, causing severe inflammatory responses and greater oxidative stress, with transcriptomic analysis revealing contrasting gene expression patterns between the two particle sizes.

2022 Aquatic Toxicology 35 citations
Article Tier 2

Suborganismal responses of the aquatic midge Chironomus riparius to polyethylene microplastics

Researchers exposed Chironomus riparius larvae to polyethylene microplastics and used transcriptomics and metabolomics to characterize suborganismal responses, finding disruption of oxidative stress pathways, energy metabolism, and cuticle synthesis — effects not captured by standard life-history endpoints alone.

2021 The Science of The Total Environment 44 citations
Article Tier 2

Transcriptome alterations in zebrafish gill after exposure to different sizes of microplastics

Researchers found that microplastic exposure in zebrafish gills caused size-dependent transcriptomic changes, with smaller particles triggering more differentially expressed genes related to immune response, oxidative stress, and apoptosis pathways compared to larger particles.

2022 Journal of Environmental Science and Health Part A 36 citations
Article Tier 2

Metabolomics revealing the response of rice (Oryza sativa L.) exposed to polystyrene microplastics

Researchers used metabolomics to investigate how polystyrene microplastics affect rice plants through both laboratory and field experiments. The study found that microplastic exposure reduced shoot biomass in a dose-dependent manner and altered antioxidant enzyme activity, suggesting that microplastics in agricultural soil can stress crops through measurable metabolic changes.

2020 Environmental Pollution 265 citations
Article Tier 2

The effects of exposure to microplastics on grass carp (Ctenopharyngodon idella) at the physiological, biochemical, and transcriptomic levels

Researchers exposed grass carp to microplastics at two concentrations for 21 days and observed liver damage, inhibited growth, and increased oxidative stress. Transcriptome analysis revealed over 1,500 differentially expressed genes related to immune response, metabolism, and cellular stress pathways. The study suggests that microplastic exposure can trigger broad physiological and molecular disruptions in freshwater fish.

2021 Chemosphere 54 citations
Article Tier 2

Polystyrene nanoplastic induces oxidative stress, immune defense, and glycometabolism change in Daphnia pulex: Application of transcriptome profiling in risk assessment of nanoplastics

Researchers used transcriptome sequencing to examine how polystyrene nanoplastics affect gene expression in the water flea Daphnia pulex. After 96 hours of exposure, they identified 208 genes with altered expression levels, linked to oxidative stress, immune defense, and sugar metabolism pathways. The study provides molecular-level evidence that nanoplastic pollution can trigger multiple stress responses in freshwater organisms.

2020 Journal of Hazardous Materials 167 citations
Article Tier 2

Comparative Transcriptome Combined with Morphophysiological Analyses Revealed Carotenoid Biosynthesis for Differential Chilling Tolerance in Two Contrasting Rice (Oryza sativa L.) Genotypes

Researchers used comparative transcriptomics to find that carotenoid biosynthesis is a critical pathway for cold tolerance in rice, with cold-tolerant varieties showing higher carotenoid gene expression and pigment accumulation that protects chloroplasts during chilling stress. This study focuses on plant biology and crop science with no direct connection to microplastic research.

2023 Research Square (Research Square)
Article Tier 2

Toxicity of environmental and polystyrene plastic particles on the bivalve Corbicula fluminea: focus on the molecular responses

Researchers exposed freshwater bivalves to environmental microplastics and nanoplastics collected from a river, as well as to laboratory polystyrene nanoparticles, and measured molecular-level responses. Gene expression analysis revealed that plastic particle exposure activated stress response and immune defense pathways in gill and visceral tissues. The study indicates that even environmentally relevant concentrations of plastic particles can trigger measurable biological stress in filter-feeding organisms.

2024 Ecotoxicology 2 citations
Article Tier 2

Toxicological effects and transcriptome mechanisms of rice (Oryza sativa L.) under stress of quinclorac and polystyrene nanoplastics

Researchers found that combined exposure to polystyrene nanoplastics and the herbicide quinclorac caused greater toxicity to rice than either stressor alone, with transcriptome analysis revealing disrupted pathways in photosynthesis, oxidative stress response, and hormone signaling.

2022 Ecotoxicology and Environmental Safety 25 citations
Article Tier 2

Oxidative stress and metabolic process responses of Chlorella pyrenoidosa to nanoplastic exposure: Insights from integrated analysis of transcriptomics and metabolomics

Researchers used integrated transcriptomics and metabolomics to reveal that the microalgae Chlorella pyrenoidosa responds to nanoplastic oxidative stress primarily through linoleic acid, glycine-serine-threonine, and arginine-proline metabolic pathways, identifying key driver genes that could be targeted through genetic engineering to reduce nanoplastic harm in aquatic ecosystems.

2024 Environmental Pollution 17 citations
Article Tier 2

Decoding the molecular concerto: Toxicotranscriptomic evaluation of microplastic and nanoplastic impacts on aquatic organisms

This review summarizes existing research on how microplastics and nanoplastics affect gene activity in aquatic organisms including fish, crustaceans, and mollusks. The studies show that these tiny particles disrupt genes involved in immune defense, stress response, reproduction, and metabolism. Understanding these molecular-level changes is important because they reveal how microplastics could cause long-term health problems in animals that enter the human food chain.

2024 Journal of Hazardous Materials 15 citations
Article Tier 2

Combined effect of microplastics and tire particles on Daphnia magna: Insights from physiological and transcriptomic responses

Researchers investigated the combined effects of microplastics and tire particles on the water flea Daphnia magna, finding that the mixture triggered significant oxidative stress at environmentally relevant concentrations. Transcriptomic analysis revealed upregulation of antioxidant and metabolic stress genes, while energy reserves like glycogen were affected. The study suggests that co-exposure to these common freshwater pollutants may pose greater ecological risks than either particle type alone.

2025 Environmental Pollution 1 citations
Article Tier 2

The effects of Micro/Nano-plastics exposure on plants and their toxic mechanisms: A review from multi-omics perspectives.

A multi-omics review of micro/nanoplastic effects on plants found that plastic exposure disrupts gene expression, protein function, and metabolic pathways across multiple plant systems, with potential consequences for crop yield and agricultural food safety.

2024 Journal of hazardous materials
Article Tier 2

Transcriptomic and metabolomic changes in lettuce triggered by microplastics-stress

Researchers grew lettuce in water containing polystyrene microplastics and found that the particles accumulated in root tips and leaf veins, causing water loss stress and changes in gene expression. The plants responded by activating stress defense systems and altering their metabolism, including increased production of protective compounds in root secretions. This study provides molecular-level evidence that microplastics can stress food crops and change their biology, raising questions about the safety and nutritional quality of vegetables grown in contaminated environments.

2023 Environmental Pollution 107 citations
Article Tier 2

Comparative Transcriptome Combined with Morphophysiological Analyses Revealed Carotenoid Biosynthesis for Differential Chilling Tolerance in Two Contrasting Rice (Oryza sativa L.) Genotypes

This paper is not about microplastics; it uses comparative transcriptomics and physiological analysis to investigate how two rice cultivars differ in their tolerance to cold-stress-induced leaf chlorosis.

2023 Rice 6 citations
Article Tier 2

The Growth Inhibition of Polyethylene Nanoplastics on the Bait-Microalgae Isochrysis galbana Based on the Transcriptome Analysis

Researchers found that polyethylene nanoplastics (50 nm) significantly inhibited growth and reduced chlorophyll in the bait microalga Isochrysis galbana through oxidative stress and disrupted gene expression, while larger microplastics had no significant impact.

2023 Microorganisms 39 citations
Article Tier 2

Rhizosphere nutrient dynamics and physiological responses of Oryza sativa L. under polyethylene terephthalate microplastic stress

Researchers exposed rice (Oryza sativa) to PET microplastics and found that the particles were absorbed by roots and translocated to aerial tissues, significantly inhibiting chlorophyll production, inducing oxidative stress (with malondialdehyde increasing by 175% at higher doses), and disrupting nitrogen, carbon, and phosphorus cycling genes in the rhizosphere.

2025 Plant Physiology and Biochemistry
Article Tier 2

Multi‐Omics Insights Into Phenylpropanoid and Lipid Barrier Biosynthesis in Maize Roots Under Salt and Microplastic Stresses

Researchers used transcriptomic and metabolomic analyses to investigate how polystyrene microplastics and salt stress — individually and in combination — affect phenylpropanoid and lipid barrier biosynthesis in maize seedling roots, finding that combined stresses alter molecular defence pathways in ways distinct from either stressor alone.

2025 Physiologia Plantarum
Article Tier 2

Polyethylene microbeads induce transcriptional responses with tissue-dependent patterns in the mussel Mytilus galloprovincialis

Researchers exposed fish to polyethylene microbeads and measured gene expression across tissues, finding tissue-dependent transcriptional responses that suggest microplastic ingestion affects multiple physiological systems in distinct ways.

2017 Journal of Molluscan Studies 90 citations
Article Tier 2

Lipid Metabolism and Oxidative Stress Altered in Crucian Carp (Carassius auratus) Following Exposure to Microplastics Under Laboratory and Field Conditions

Researchers used high-throughput sequencing to assess the impact of microplastics on crucian carp under both field and laboratory conditions. After four weeks of in-situ exposure, intestinal microplastic levels slightly increased, and transcriptome analysis revealed over 3,000 differentially expressed genes in the liver, with notable enrichment in pathways related to lipid metabolism and oxidative stress.

2026 Water
Article Tier 2

Transcriptional effects of polyethylene microplastics ingestion in developing zebrafish (Danio rerio)

Researchers exposed developing zebrafish to polyethylene microplastics and used transcriptomic analysis to identify changes in gene expression related to immune function, lipid metabolism, and oxidative stress. The study suggests that even at relatively low concentrations, ingested microplastics can alter key biological pathways during early fish development.

2018 Environmental Pollution 176 citations