Papers

61,005 results
|
Article Tier 2

A Review on Biological Synthesis of the Biodegradable Polymers Polyhydroxyalkanoates and the Development of Multiple Applications

This review covers the biological production of polyhydroxyalkanoates, a family of biodegradable bioplastics that bacteria naturally produce from waste carbon sources. Researchers found that these biopolymers have properties similar to conventional plastics like polypropylene but can fully biodegrade, making them a promising alternative to petroleum-based plastics. The study emphasizes that scaling up production and establishing proper end-of-life management are critical steps for PHAs to compete with conventional plastics and help reduce microplastic pollution.

2022 Catalysts 169 citations
Article Tier 2

Polyhydroxyalkanoates (PHAs) – Production, Properties, and Biodegradation

This review covers polyhydroxyalkanoates (PHAs), a class of microbially produced biopolyesters, discussing raw material innovation, microbial producer strains, bioengineering approaches for improved yields, and end-of-life biodegradation options. PHAs are presented as a genuinely circular plastic alternative due to their renewable production, biodegradability, and compatibility with existing plastic applications including food packaging.

2022 15 citations
Article Tier 2

Polyhydroxyalkanoates biosynthesis, resulting polymer structures, and plasticization

This review examines polyhydroxyalkanoates (PHAs), a class of biodegradable biopolymers synthesized by microorganisms, discussing strategies including plasticizers and monomer inclusion to overcome the brittleness and processing challenges of the most common PHA, poly(3-hydroxybutyrate).

2024
Article Tier 2

Biosynthesis of Polyhydroxyalkanoates (PHAs) by the Valorization of Biomass and Synthetic Waste

This paper explores the production of polyhydroxyalkanoates (PHAs), biodegradable microbial polymers, from biomass and waste feedstocks as a sustainable alternative to conventional synthetic plastics. PHAs can be naturally synthesized by bacteria, offering a pathway to biodegradable plastics that do not persist as microplastic pollution.

2020 Molecules 47 citations
Article Tier 2

Strategies for Biosynthesis of C1 Gas-derived Polyhydroxyalkanoates: A review

Researchers reviewed strategies for producing polyhydroxyalkanoates (PHAs) — biodegradable bioplastics — from one-carbon gases like CO2, CO, and methane using autotrophic and methanotrophic microbes, highlighting fermentation and metabolic engineering approaches as cost-effective alternatives to conventional carbon-source-dependent PHA production.

2021 Bioresource Technology 35 citations
Article Tier 2

Polyhydroxyalkanoate (PHA) Bio-polyesters – Circular Materials for Sustainable Development and Growth

This review examines polyhydroxyalkanoate (PHA) biopolymers as circular carbon materials produced from renewable feedstocks and biodegradable across diverse environments, arguing that PHAs offer a more genuine solution to microplastic pollution than conventional bioplastics that require industrial composting.

2023 Chemical and Biochemical Engineering Quarterly 21 citations
Article Tier 2

A review on polyhydroxyalkanoate (PHA) production through the use of lignocellulosic biomass

This review examines the process of producing polyhydroxyalkanoate (PHA) bioplastics from lignocellulosic biomass. The study covers the full production chain from biomass pre-treatment to PHA extraction, exploring pathways for cost-effective biodegradable plastic production.

2023 RSC Sustainability 90 citations
Article Tier 2

Chemical and Biochemical Engineering Approaches in Manufacturing Polyhydroxyalkanoate (PHA) Biopolyesters of Tailored Structure with Focus on the Diversity of Building Blocks

This review examines chemical and biochemical engineering strategies for manufacturing polyhydroxyalkanoates (PHAs) with tailored structures, covering short-, medium-, and long-chain PHA homo-, co-, ter-, and quarterpolyesters produced from diverse microbial feedstocks. Researchers found that monomeric composition and biosynthesis conditions are the primary determinants of PHA material properties, enabling design of biopolymers that closely mimic conventional thermoplastics and elastomers.

2019 Chemical and Biochemical Engineering Quarterly 77 citations
Article Tier 2

Current trends in the production of biodegradable bioplastics: The case of polyhydroxyalkanoates

This review evaluates the state of polyhydroxyalkanoate (PHA) bioplastic production, comparing microbiological, enzymatic, and chemical manufacturing approaches for their potential to replace petroleum-based plastics. While PHAs are naturally biodegradable and mechanically versatile, cost and scalability remain major barriers to commercial adoption.

2020 Biotechnology Advances 130 citations
Article Tier 2

Beyond Intracellular Accumulation of Polyhydroxyalkanoates: Chiral Hydroxyalkanoic Acids and Polymer Secretion

This review covers polyhydroxyalkanoates (PHAs), biodegradable plastics produced by bacteria, which have potential as environmentally friendly alternatives to conventional petroleum-based plastics. Despite their versatility, PHAs remain expensive to produce at scale, limiting their commercial adoption.

2020 Frontiers in Bioengineering and Biotechnology 34 citations
Article Tier 2

Advances in Polyhydroxyalkanoate (PHA) Production, Volume 3

This review synthesizes advances in polyhydroxyalkanoate (PHA) biopolyester production as a family of biodegradable alternatives to conventional plastics, addressing growing public concern about plastic waste and microplastic formation by examining the latest research on PHA synthesis from fossil-free feedstocks.

2022 9 citations
Article Tier 2

Exploiting sugar-rich feedstocks for sustainable polyhydroxyalkanoate production

Researchers investigated the use of sugar-rich agricultural feedstocks for sustainable production of polyhydroxyalkanoates (PHAs), evaluating these bacterial biopolymers as biodegradable alternatives to petrochemical plastics that contribute to microplastic pollution.

2025 Circular Agricultural Systems
Article Tier 2

PHA-Based Bioplastic: a Potential Alternative to Address Microplastic Pollution

This review examines polyhydroxyalkanoate (PHA)-based bioplastics as biodegradable alternatives to petroleum-derived plastics, highlighting their potential to reduce microplastic pollution while discussing challenges in scaling production and improving material properties.

2022 Water Air & Soil Pollution 172 citations
Article Tier 2

Novel Technologies for Polyhydroxyalkanoates (PHA) Production

This review examines novel production technologies for polyhydroxyalkanoates, highlighting how the global problem of plastic and microplastic pollution has intensified interest in developing scalable, eco-friendly bioplastic alternatives over more than four decades of PHA research.

2025 Apple Academic Press eBooks
Article Tier 2

Insightful Advancement and Opportunities for Microbial Bioplastic Production

This review surveys advances in microbial production of polyhydroxyalkanoates (PHAs) and other bioplastics, highlighting fermentation optimization, feedstock diversification, and genetic engineering strategies that could make microbially-derived bioplastics economically competitive with petroleum-based plastics.

2022 Frontiers in Microbiology 39 citations
Article Tier 2

Polyhydroxyalkanoate (PHA) Biopolyesters - Emerging and Major Products of Industrial Biotechnology

This review examined polyhydroxyalkanoate biopolyesters as industrially produced biodegradable plastics, covering their microbial biosynthesis, material properties, and commercial applications as sustainable alternatives to conventional petroleum-based plastics.

2022 The EuroBiotech Journal 23 citations
Article Tier 2

Bacterial Production of Hydroxyalkanoates (PHA)

This review examines bacterial production of polyhydroxyalkanoates (PHA) as a biodegradable alternative to petroleum-based plastics, covering fermentation processes, scaling to industrial levels, and future trends, while noting that higher production costs currently prevent PHAs from competing commercially with conventional plastics.

2016 Universal Journal of Microbiology Research 32 citations
Article Tier 2

Post-Transcriptional Control in the Regulation of Polyhydroxyalkanoates Synthesis

This review examines how gene regulation controls the production of polyhydroxyalkanoates (PHAs), a family of biodegradable bioplastics made by bacteria. Better understanding of these biological controls could help scale up manufacturing of eco-friendly alternatives to conventional petroleum-based plastics.

2021 Life 6 citations
Article Tier 2

The synthesis of polyhydroxyalkanoates from low carbon wastewater under anaerobic-microaerobic process: effects of pH and nitrogen and phosphorus limitation

Researchers optimized conditions for producing polyhydroxyalkanoates (PHAs) — biodegradable bioplastics — from wastewater using bacteria under anaerobic-microaerobic conditions. Controlling pH and nutrient levels significantly improved PHA production yield. This work advances the development of sustainable plastic alternatives made from waste materials.

2021 Environmental Engineering Research 13 citations
Article Tier 2

Polyhydroxyalkanoates – Linking Properties, Applications and End-of-life Options

This review presents polyhydroxyalkanoate biopolyesters as a leading class of genuinely biodegradable bioplastics, linking their material properties and diverse applications to end-of-life options while addressing legislative confusion in the broader bioplastics landscape.

2020 Chemical and Biochemical Engineering Quarterly 78 citations
Article Tier 2

Production of biopolymers from microalgae and cyanobacteria

This review examines the production of biopolymers, particularly polyhydroxyalkanoates (PHAs), from microalgae and cyanobacteria as sustainable alternatives to conventional petroleum-based plastics, synthesizing studies on biomass accumulation and production pathways. The authors discuss the properties, applications, and scalability challenges of microalgae- and cyanobacteria-derived bioplastics in the context of reducing plastic pollution and fossil fuel dependence.

2023 IWA Publishing eBooks 4 citations
Article Tier 2

Current developments on polyhydroxyalkanoates synthesis by using halophiles as a promising cell factory

Researchers reviewed how salt-loving microorganisms called halophiles can serve as efficient biological factories for producing polyhydroxyalkanoates (PHAs), a class of biodegradable plastics that could replace petroleum-based plastics. Their high salt requirements naturally prevent contamination during large-scale fermentation, and advances in metabolic engineering are making PHA production cheaper and more scalable.

2020 Microbial Cell Factories 219 citations
Article Tier 2

Recent trends of biotechnological production of polyhydroxyalkanoates from C1 carbon sources

This review examines recent advances in producing polyhydroxyalkanoates, biodegradable alternatives to conventional plastics, from C1 carbon sources like methane, methanol, and CO2 using various biotechnological approaches.

2023 Frontiers in Bioengineering and Biotechnology 38 citations
Article Tier 2

Production of polyhydroxyalkanoate (PHA) biopolymer from crop residue using bacteria as an alternative to plastics: a review

This review examines how PHA, a biodegradable plastic made from crop waste using bacteria, could serve as a sustainable alternative to conventional plastics. While PHA breaks down naturally unlike traditional plastics that fragment into microplastics, challenges remain in making it heat-stable and cost-competitive enough for widespread industrial use.

2025 RSC Advances 22 citations