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Production of polyhydroxyalkanoate (PHA) biopolymer from crop residue using bacteria as an alternative to plastics: a review

RSC Advances 2025 22 citations

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This review examines how PHA, a biodegradable plastic made from crop waste using bacteria, could serve as a sustainable alternative to conventional plastics. While PHA breaks down naturally unlike traditional plastics that fragment into microplastics, challenges remain in making it heat-stable and cost-competitive enough for widespread industrial use.

Polymers
Models
Study Type Environmental

Growing environmental concerns and the pressing need to combat plastic pollution have led to extensive research on sustainable alternatives to traditional plastics. Human blood sample analysis discovered microplastics which has caused health concerns regarding their influence on proper functioning of the human body. The compound polyhydroxyalkanoate (PHA) has gained popularity due to its comparable structure with synthetic polymers like polypropylene because it belongs to the category of biodegradable alternatives. Different PHA molecules have distinct properties because of their composition of monomers and production parameters. The current market offers an array of biopolymers but they do not satisfy industrial requirements regarding thermostability. The industrial heat-stability of materials comes from green biomass-derived polyethylene and extrudable cellulose biopolymers. The research analyses PHAs' suitability as synthetic plastic substitutes and addresses barriers to their industrial production and proposes modifications to improve performance. It underscores the importance of harnessing crop residue streams to produce valuable biopolymers, promoting resource efficiency and mitigating the environmental impact of plastic waste. This work aligns with the UN's sustainability goals, including SDG 3 good health, SDG 11 sustainable cities, SDG 12 responsible consumption, SDG 13 climate action, and SDG 14 sea and ocean protection.

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Bacterial Production of Hydroxyalkanoates (PHA)

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This review examines bacterial production of polyhydroxyalkanoates (PHA) as a biodegradable alternative to petroleum-based plastics, covering fermentation processes, scaling to industrial levels, and future trends, while noting that higher production costs currently prevent PHAs from competing commercially with conventional plastics.

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This review examined polyhydroxyalkanoate biopolyesters as industrially produced biodegradable plastics, covering their microbial biosynthesis, material properties, and commercial applications as sustainable alternatives to conventional petroleum-based plastics.

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PHA-Based Bioplastic: a Potential Alternative to Address Microplastic Pollution

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This review examines polyhydroxyalkanoate (PHA)-based bioplastics as biodegradable alternatives to petroleum-derived plastics, highlighting their potential to reduce microplastic pollution while discussing challenges in scaling production and improving material properties.

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Efficient biosynthesis and recovery of polyhydroxyalkanoate

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This review examines the biosynthesis and recovery of polyhydroxyalkanoate (PHA), a microbially-produced biodegradable bioplastic that could replace petrochemical plastics and reduce microplastic pollution. The main barrier to commercialization is production cost, and the paper discusses strategies for making PHA economically viable at scale.

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Current trends in the production of biodegradable bioplastics: The case of polyhydroxyalkanoates

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This review evaluates the state of polyhydroxyalkanoate (PHA) bioplastic production, comparing microbiological, enzymatic, and chemical manufacturing approaches for their potential to replace petroleum-based plastics. While PHAs are naturally biodegradable and mechanically versatile, cost and scalability remain major barriers to commercial adoption.

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