We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Papers
61,005 resultsShowing papers similar to Bioaccumulation and sub-chronic toxicity of microplastic environmentally relevant concentrations in Etroplus suratensis brackish water fish
ClearSub-chronic nanoplastic toxicity in Etroplus suratensis (Pisces, Cichilidae): Insights into tissue accumulation, stress and metabolic disruption
Researchers exposed pearl spot fish to polystyrene nanoplastics at different concentrations for 14 days and found that the particles accumulated in multiple organs with concentration-dependent distribution patterns. The nanoplastics caused elevated glucose and cholesterol levels, suppressed antioxidant defenses, and increased markers of oxidative damage and stress. Gene expression changes in stress response and growth-related genes suggest that nanoplastic exposure may impair both immune function and normal development in fish.
Sub-chronic exposure of Oreochromis niloticus to environmentally relevant concentrations of smaller microplastics: Accumulation and toxico-physiological responses
Researchers exposed Nile tilapia to low, environmentally relevant concentrations of polystyrene microplastics for 14 days and found the particles accumulated in multiple organs including the brain, liver, and reproductive tissues. The fish showed changes in blood chemistry, increased stress hormones, and signs of liver and kidney dysfunction. These results suggest that even realistic levels of microplastic pollution can cause measurable physiological harm in fish.
Effects of Polystyrene Microplastic Exposure on Liver Cell Damage, Oxidative Stress, and Gene Expression in Juvenile Crucian Carp (Carassius auratus)
Researchers exposed young crucian carp to polystyrene microplastics at different concentrations and found dose-dependent liver damage, with higher concentrations causing more severe tissue injury and weaker antioxidant defenses. The microplastics disrupted genes involved in detoxification and stress response in liver cells. Since crucian carp is a commonly consumed freshwater fish, these findings raise questions about whether microplastic-contaminated fish could affect the health of people who eat them.
Polystyrene microplastics exposure in freshwater fish, Labeo rohita: evaluation of physiology and histopathology
Researchers fed freshwater fish varying levels of polystyrene microplastics for 90 days and found dose-dependent damage to blood health, growth, and organ tissues. Higher microplastic concentrations caused more severe harm to the liver, kidneys, gills, and intestines. The study highlights that microplastics in freshwater systems can accumulate in fish and cause significant health problems, raising concerns about food safety for communities that rely on freshwater fish.
Enrichment of polystyrene microplastics induces histological damage, oxidative stress, Keap1-Nrf2 signaling pathway-related gene expression in loach juveniles (Paramisgurnus dabryanus)
Researchers studied how polystyrene microplastics accumulate in loach juveniles raised in ponds lined with plastic film, finding dose-dependent enrichment in the fish. The study found that microplastic exposure caused liver tissue damage, disrupted antioxidant enzyme activity, and altered the expression of genes involved in oxidative stress defense pathways.
Toxic effects of microplastic (polyethylene) exposure: Bioaccumulation, hematological parameters and antioxidant responses in crucian carp, Carassius carassius
Researchers exposed crucian carp to polyethylene microplastics at various concentrations and found that the particles accumulated in tissues including gills, gut, and liver. The microplastics altered blood cell counts and disrupted the fish's antioxidant defense system in a dose-dependent manner. The study suggests that even common polyethylene microplastics can cause measurable biological harm in freshwater fish.
Accumulation, tissue distribution, and biochemical effects of polystyrene microplastics in the freshwater fish red tilapia (Oreochromis niloticus)
Researchers exposed freshwater tilapia to polystyrene microplastics at varying concentrations for two weeks and tracked where the particles accumulated in the body. The microplastics concentrated primarily in the gut and gills, but also reached the liver and brain, with accumulation increasing over time and at higher doses. The study found that the particles caused oxidative stress and altered enzyme activity in the fish, indicating that even short-term microplastic exposure can trigger measurable biological harm in freshwater species.
Effect of Polystyrene Microplastic Exposure on Individual, Tissue, and Gene Expression in Juvenile Crucian Carp (Carassius auratus)
Juvenile crucian carp were exposed to polystyrene microplastics at different concentrations, and researchers found that the particles accumulated mainly in the intestines and gills. The study suggests that microplastic exposure caused tissue damage to multiple organs and altered gene expression, with higher concentrations generally leading to more severe effects.
Polystyrene microplastics cause tissue damages, sex-specific reproductive disruption and transgenerational effects in marine medaka (Oryzias melastigma)
Researchers exposed marine medaka fish to environmentally realistic concentrations of polystyrene microplastics and found tissue damage, oxidative stress, and sex-specific reproductive disruption. The effects carried over to the next generation even without direct microplastic exposure. The study provides evidence that microplastics at levels found in the ocean can cause lasting biological harm across generations in fish.
Ecotoxicological effects of polystyrene nanoplastics on common carp: Insights into blood parameters, DNA damage, and gene expression
Exposing common carp to polystyrene nanoplastics caused significant DNA damage in blood and brain cells, along with changes in genes related to immune function and stress response. Higher concentrations led to more severe effects, and the nanoplastics also disrupted liver antioxidant defenses. Since carp are widely consumed fish, these findings raise questions about the safety of fish from nanoplastic-contaminated waters for human consumption.
Polystyrene microplastics enhance the microcystin-LR-induced gonadal damage and reproductive endocrine disruption in zebrafish
Zebrafish exposed to polystyrene microplastics along with microcystin-LR (a common toxin from algae blooms) suffered worse reproductive damage than when exposed to either pollutant alone. The microplastics acted as carriers that increased the amount of toxin accumulating in the fish's reproductive organs. This study demonstrates that microplastics can worsen the effects of other water pollutants by helping toxic chemicals build up in the body.
Polystyrene microparticles can affect the health status of freshwater fish – Threat of oral microplastics intake
Researchers fed juvenile rainbow trout polystyrene microplastics at three dietary concentrations for six weeks and assessed multiple health parameters. They found that the highest concentration triggered immune responses, liver and gill damage, disrupted antioxidant balance, and reduced plasma proteins. The study demonstrates that oral microplastic intake can negatively affect the health of freshwater fish across multiple organ systems.
Microplastics induce toxic effects in fish: Bioaccumulation, hematological parameters and antioxidant responses
Researchers exposed juvenile fish to polyamide microplastics and found the particles accumulated primarily in the intestine, gills, and liver, causing reduced blood oxygen-carrying capacity, liver stress, and disrupted antioxidant defenses. These findings matter because fish are an important food source for humans, and microplastic accumulation in fish tissues could transfer these contaminants to people through their diet.
Analysis of the Biochemical and Histopathological Impact of Polystyrene Microplastic on Channa Punctata (Bloch, 1793) Fish.
Researchers exposed snakehead fish (Channa punctata) to polystyrene microplastics at three doses for 28 days, finding dose-dependent liver and kidney damage, elevated stress enzymes, and histopathological changes — indicating significant biochemical toxicity in freshwater fish.
A dosage-effect assessment of acute toxicology tests of microplastic exposure in filter-feeding fish
Researchers assessed the dose-dependent effects of polystyrene microplastics on silver carp, a filter-feeding fish, during a 48-hour exposure and recovery period. Low concentrations induced oxidative stress and gene upregulation in the intestine, with the fish able to recover after exposure ended. However, high concentrations caused significant gill and intestinal damage that persisted even after the microplastics were removed.
Uptake and Accumulation of Polystyrene Microplastics in Zebrafish (Danio rerio) and Toxic Effects in Liver
Researchers exposed zebrafish to polystyrene microplastics of two different sizes and tracked where the particles accumulated in the body. They found that smaller particles (5 micrometers) built up in the gills, liver, and gut, while larger particles (20 micrometers) mainly stayed in the gills and gut. The microplastics caused liver inflammation, oxidative stress, and disrupted fat metabolism, suggesting that ingested microplastics can damage internal organs in fish.
Toxicity and Functional Tissue Responses of Two Freshwater Fish after Exposure to Polystyrene Microplastics
Researchers exposed zebrafish and perch to polystyrene microplastics for 21 days and assessed tissue-level damage using a battery of biomarkers. They found that the microplastics caused oxidative stress, DNA damage, and activated cell death pathways in both gill and liver tissues. The study suggests that gills are more sensitive to microplastic exposure than liver tissue for most measured parameters, with DNA damage being the most responsive biomarker overall.
Toxic impact of polystyrene microplastic particles in freshwater organisms
Researchers tested the toxic effects of polystyrene microplastics on four freshwater species including algae, rotifers, crustaceans, and ostracods. They found that water fleas were the most sensitive, with chronic effects appearing at very low concentrations, and that microplastics caused both DNA damage and increased production of reactive oxygen species. The study highlights that even at relatively low concentrations, microplastics can pose a meaningful threat to freshwater ecosystems.
Influence of Polystyrene Microplastics on Mitochondrial Oxidative Damage in Renal and Muscular Tissues of the Freshwater Fish
Researchers exposed freshwater fish to environmentally relevant concentrations of polystyrene microplastics for up to 15 days and examined mitochondrial damage in kidney and muscle tissues. The exposure disrupted antioxidant defenses, increased oxidative stress, and altered metabolic enzyme activities in both tissue types. Histological examination revealed significant tissue damage including necrosis and degeneration, suggesting that microplastics can cause organ-level toxicity in fish through mitochondrial oxidative stress.
Polystyrene nanospheres-induced hepatotoxicity in swamp eel (Monopterus albus): From biochemical, pathological and transcriptomic perspectives
Researchers exposed swamp eels to polystyrene nanoplastics for 28 days and found significant liver damage including oxidative stress, tissue abnormalities, and disrupted gene expression related to immune response and metabolism. Higher concentrations caused more severe liver injury, with changes detectable at both the biochemical and genetic levels. This study adds evidence that nanoplastic exposure can harm liver function in freshwater species important to aquaculture and local food supplies.
Dose-Dependent Cytotoxicity of Polypropylene Microplastics (PP-MPs) in Two Freshwater Fishes
Researchers fed zebrafish and freshwater perch polypropylene microplastics at low and high doses and measured cellular damage in liver and gill tissues. They found dose-dependent toxicity including DNA damage up to 18-fold higher than controls, lipid peroxidation, and disrupted metabolism of key compounds like tryptophan. The study provides evidence that polypropylene microplastic ingestion causes significant cellular harm to freshwater fish in a dose-dependent manner.
Revealing the hidden threats: Genotoxic effects of microplastics on freshwater fish
Researchers exposed a common freshwater fish to microplastics and found evidence of DNA damage in blood cells, along with changes in liver function and oxidative stress markers. The study took a comprehensive approach, measuring effects from the molecular level up to whole-organism responses. These genotoxic effects (damage to genetic material) in fish raise questions about whether chronic microplastic exposure could pose similar risks to other organisms, including humans.
Assessment of the Accumulation and Potential Toxicity of Polystyrene Microplastics in Rats
This study assessed polystyrene microplastic accumulation in aquatic organisms and evaluated associated toxicity endpoints including oxidative stress, histological changes, and behavioral effects. Microplastics accumulated in multiple tissues and caused dose-dependent physiological harm.
Subchronic oral exposure to polystyrene microplastics affects hepatic lipid metabolism, inflammation, and oxidative balance in gilthead seabream (Sparus aurata)
Gilthead seabream fed polystyrene microplastics for 21 days developed signs of liver damage including fat buildup, inflammation, and oxidative stress -- changes similar to early-stage fatty liver disease. Since fish liver responds to microplastics in ways comparable to mammalian livers, these findings raise concerns about what chronic microplastic exposure might do to liver health in humans and other animals.