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61,005 resultsShowing papers similar to NIR-II Plastic Particles for Monitoring IntestinalMotility and Microplastic Deposition in Mice
ClearNIR-II Plastic Particles for Monitoring IntestinalMotility and Microplastic Deposition in Mice
NIR-II fluorescent plastic particles were used to monitor real-time intestinal microplastic movement and accumulation in mice, revealing that different particle sizes showed distinct deposition patterns in the gastrointestinal tract. (Duplicate record.)
NIR-II Plastic Particles for Monitoring IntestinalMotility and Microplastic Deposition in Mice
This study created NIR-II fluorescent plastic particles to study intestinal motility and microplastic deposition in live mice, demonstrating their utility for real-time in vivo tracking of microplastic behavior in the digestive tract. (Duplicate record.)
NIR-II Plastic Particles for Monitoring IntestinalMotility and Microplastic Deposition in Mice
Researchers developed NIR-II fluorescent microplastic tracers to non-invasively monitor intestinal motility and microplastic deposition in living mice, enabling real-time imaging of how plastic particles travel and accumulate within the gut. (Duplicate record.)
NIR-II Plastic Particles for Monitoring IntestinalMotility and Microplastic Deposition in Mice
Researchers developed near-infrared II (NIR-II) fluorescent plastic particles to non-invasively track microplastic movement and deposition in living mice, finding that microplastics accumulated preferentially in the intestine with slow clearance.
NIR-II Plastic Particles for Monitoring Intestinal Motility and Microplastic Deposition in Mice
Scientists developed a new imaging technique using fluorescent plastic particles to track microplastic movement through the digestive systems of living mice in real time. Healthy mice excreted 99% of the particles within 24 hours, but mice with constipation or colitis retained microplastics much longer. Long-term feeding experiments showed persistent microplastic accumulation in the intestines and spleen, providing direct visual evidence that gut health conditions may increase the body's retention of ingested plastic particles.
Near-infrared (NIR-II) fluorescent poly(ethylene terephthalate) nano-microplastics for in vivo tracking
Researchers developed a new method to track nano-microplastics inside living animals in real time using near-infrared fluorescent imaging. By embedding a special dye into common PET plastic particles, they were able to follow the particles through mice after oral exposure, offering a promising tool for studying how plastics of different sizes behave inside the body.
Synthesis of near-infrared-fluorophore-loaded microplastics with different compositions for in vivo tracking
Researchers synthesised fluorescent microplastic particles of different polymer types that can be tracked inside living animals using near-infrared imaging, creating a tool for studying how microplastics move through and accumulate within biological tissues. These model particles help researchers understand real-world microplastic behaviour inside organisms, which is critical for assessing health risks.
Digestible Fluorescent Coatings for Cumulative Quantification of Microplastic Ingestion
Researchers developed digestible fluorescent coatings for microplastic particles that allow cumulative quantification of ingestion over time, overcoming the limitation of gut-content snapshots by enabling tracking of total microplastic exposure in organisms.
Noncovalent radiolabeling of microplastics using a desferrioxamine-conjugated Nile Red derivative for quantitative in vivo tracking
Researchers developed a new method for tracking microplastics in living organisms using a specialized dye that attaches to plastic surfaces without altering their properties, enabling both fluorescence imaging and radioactive labeling. The technique allowed quantitative tracking of microplastic movement through the gastrointestinal tract of mice using PET imaging, providing a tool for better understanding how microplastics behave in the body.
Biodistribution of nanoplastics in mice: advancing analytical techniques using metal-doped plastics
Researchers developed a new analytical method using palladium-doped nanoplastics to track where plastic particles go in the body after ingestion in mice. They found that after short-term exposure, most particles passed through the digestive system and were excreted, but longer-term exposure led to accumulation in body tissues. The study advances the ability to detect and trace nanoplastics at extremely small concentrations in biological samples.
Developments in the field of intestinal toxicity and signaling pathways associated with rodent exposure to micro(nano)plastics.
This review synthesizes current research on how micro- and nano-plastics damage the intestinal epithelium, disrupt gut barrier function, and activate inflammatory signaling pathways. The findings highlight the gut as a primary site of microplastic accumulation and suggest that intestinal toxicity may link dietary microplastic exposure to systemic health effects.
Fate, uptake and impact of fit-for-purpose nanoplastics on the digestive environment: an in vitro-in vivo continuum study
Researchers investigated the fate, uptake, and impact of fluorescent and gold-labeled polystyrene nanoplastics on the digestive environment, using fit-for-purpose labeled particles to track nanoplastic behavior in biological systems. The labeled nanoplastics enabled detailed mapping of how plastic nanoparticles are processed in the gut, providing mechanistic insight into absorption pathways.
Fluorescent plastic nanoparticles to track their interaction and fate in physiological environments
This study developed fluorescently labeled plastic nanoparticles made from PET, polypropylene, and polystyrene that can be tracked in biological environments to study how nanoplastics are taken up and processed by living organisms. Having trackable model nanoplastics is an important tool for understanding how these particles move through tissues and food chains.
Challenges in assessing ecological and health risks of microplastics and nanoplastics: tracking their dynamics in living organisms
Researchers proposed a new method for tracking micro- and nanoplastics in living organisms using fluorescent monomers built directly into the plastic particles during synthesis. Current detection methods require destructive sampling and only provide static snapshots, missing the real-time movement of particles through biological systems. This fluorescent monomer approach is designed to enable continuous, stable imaging of plastic particles as they move through complex biological environments.
Near-Infrared-II In Vivo Visualization and Quantitative Tracking of Micro/Nanoplastics in Fish
Scientists developed a new near-infrared imaging technique to track micro- and nanoplastics inside living zebrafish in real time, overcoming limitations of previous detection methods. They found that both sizes of plastic particles accumulated mainly in the gut, with microplastics concentrating more in the front sections and nanoplastics distributing more evenly. This tracking tool helps researchers better understand how plastic particles move through and accumulate in living organisms, which is essential for assessing the risks of microplastic exposure.
Visible Combined Near-Infrared in Situ Imaging Revealed Dynamic Effects of Microplastic Fibers and Beads in Zebrafish
Researchers used a combined visible and near-infrared imaging technique to track microplastic fibers and beads in live zebrafish in real time. They observed that microplastics were quickly ingested and could be retained briefly in the digestive tract before being eliminated. The study provides new insights into the dynamic behavior of microplastics inside living organisms and whether any tissue damage that occurs during transit can be reversed.
Fate, uptake and impact of fit-for-purpose nanoplastics on the digestive environment: an in vitro-in vivo continuum study
Researchers used fluorescently and gold-labeled polystyrene nanoplastics as models to study how these particles behave in the digestive environment and what effects they have on gut health. The study revealed that nanoplastics interact with the digestive system in ways that depend on particle labeling and surface properties.
In Vivo Tissue Distribution of Microplastics and the Systemic Metabolic Changes After Gastrointestinal Exposure in Mice
Mice exposed to microplastics via the gastrointestinal route showed systemic distribution of particles to multiple organs and measurable changes in metabolic pathways, providing early in vivo evidence of systemic impacts from plastic ingestion.
In Vivo visualization of microplastic degradability and intestinal functional responses in a plastivore insect
Researchers developed near-infrared fluorescent microplastics to visualize real-time plastic degradation inside the gut of mealworm larvae (Tenebrio molitor), a known plastic-eating insect. They found that smaller microplastics were digested and passed more quickly than larger ones, and that the larvae actively modulated reactive nitrogen species levels in response to microplastic biodegradation.
Toxicity Study and Quantitative Evaluation of Polyethylene Microplastics in ICR Mice
Researchers fed polyethylene microplastics to mice over 28 days to study their toxicity, and used Raman spectroscopy to track where the particles ended up. They detected microplastics in the lungs, stomach, intestines, and blood serum, with repeated oral exposure leading to inflammation in lung tissue. The findings provide evidence that ingested microplastics can travel beyond the gut and accumulate in other organs.
Visualizing the internalization and biological impact of nanoplastics in live intestinal organoids by Fluorescence Lifetime Imaging Microscopy (FLIM)
Researchers developed a new imaging method using fluorescence lifetime microscopy to track nanoplastics inside living intestinal tissue grown from stem cells, finding that even pristine (unweathered) PMMA and polystyrene nanoparticles disrupted mitochondrial function and triggered inflammation in gut cells within just three days.
Distribution and Tissue Damage After a Single Microplastic Exposure in Mice
Researchers administered fluorescent microplastics to mice by oral gavage and tracked their distribution through the body over several hours. They found direct evidence of microplastic particles in the blood, lungs, brain, kidneys, liver, and spleen, with fluorescence peaking at two hours after exposure. Histological examination revealed mild tissue damage including congestion in the liver and lungs, providing evidence that ingested microplastics can enter the bloodstream and reach multiple organs.
Microplastic effects on mouse colon in normal and colitis conditions: A literature review
This literature review examined studies on how microplastic exposure affects the mouse colon under both normal and inflammatory conditions. Evidence indicates that microplastics may contribute to intestinal inflammation and could worsen existing colitis. The review highlights the need for further research to better understand how microplastic ingestion may influence gut health in humans.
MRI-based microplastic tracking in vivo and targeted toxicity analysis
Researchers developed a new MRI-based method to track microplastics inside living mice over 21 days. They found that the liver was the primary organ where polystyrene microplastics accumulated, and this accumulation led to liver cell death, inflammation, and changes in enzyme levels. This tracking technique could help scientists better understand how microplastics move through and affect biological systems.