Papers

61,005 results
|
Article Tier 2

Hydrolytic Degradation of Polyethylene Terephthalate by Cutinase Enzyme Derived from Fungal Biomass–Molecular Characterization

Researchers isolated cutinase and lipase enzymes from Aspergillus tamarii and Penicillium crustosum fungi and demonstrated their ability to catalyze hydrolytic degradation of PET plastic, offering a potential biological route for plastic waste breakdown.

2021 Biointerface Research in Applied Chemistry 37 citations
Article Tier 2

Development of a yeast whole-cell biocatalyst for MHET conversion into terephthalic acid and ethylene glycol

Researchers engineered baker's yeast to display plastic-degrading enzymes on its cell surface, demonstrating a simpler and potentially cheaper approach to breaking down PET plastic — the material used in bottles — without requiring the costly step of purifying the enzymes first.

2022 Microbial Cell Factories 20 citations
Article Tier 2

Acceleration a yeast-based biodegradation process of polyethylene terephthalate microplastics by Tween 20: Efficiency, by-product analysis, and metabolic pathway Prediction

Researchers isolated a new yeast strain capable of degrading polyethylene terephthalate microplastics and found that adding the surfactant Tween 20 significantly accelerated the biodegradation process. The yeast changed the microplastic surface charge and reduced particle size, with Tween 20 enhancing the breakdown efficiency. The study suggests that surfactant-assisted biological approaches may offer a promising avenue for addressing PET microplastic pollution.

2024 Environmental Pollution 15 citations
Article Tier 2

Polyethylene Terephthalate Hydrolases in Human Gut Microbiota and Their Implications for Human Health

Researchers searched the genomes of healthy human gut bacteria and discovered enzymes capable of breaking down PET, one of the most common plastics found in food and drink packaging. They identified multiple bacterial species in the human gut that produce these PET-degrading enzymes. This discovery suggests that gut microbes may play a role in processing the microplastics people swallow, though it also raises questions about whether the breakdown products could affect human health.

2024 Microorganisms 13 citations
Article Tier 2

Enzymatic Degradation of Polyethylene Terephthalate Plastics by Bacterial Curli Display PETase

Researchers engineered bacteria to display a PET-degrading enzyme on their surface, creating a reusable biocatalyst capable of breaking down polyethylene terephthalate plastics. The system worked under various conditions, remained stable for at least 30 days, and could even degrade PET microplastics in wastewater and highly crystalline consumer plastic waste. This biological approach offers a promising environmentally friendly alternative for plastic recycling and waste treatment.

2022 Environmental Science & Technology Letters 85 citations
Article Tier 2

Targeted aggregation of PETase towards surface of Stenotrophomonas pavanii for degradation of PET microplastics

Researchers developed a strategy to target PETase enzyme to the surface of Stenotrophomonas pavanii bacteria, improving the efficiency of in-situ PET microplastic degradation. Surface-displayed PETase showed significantly enhanced PET hydrolysis compared to free enzyme, offering a practical approach to microbial degradation of dispersed PET microplastics in environmental settings.

2024 Journal of Hazardous Materials 9 citations
Article Tier 2

An Overview into Polyethylene Terephthalate (PET) Hydrolases and Efforts in Tailoring Enzymes for Improved Plastic Degradation

This review examines the discovery and engineering of PET-degrading enzymes including PETase and cutinase variants, discussing protein engineering strategies to improve catalytic efficiency and thermostability for practical biodegradation of polyethylene terephthalate plastic waste.

2022 International Journal of Molecular Sciences 120 citations
Article Tier 2

Enhanced degradation of polyethylene terephthalate (PET) microplastics by an engineered Stenotrophomonas pavanii in the presence of biofilm

Scientists engineered a biofilm-forming bacterium to break down PET microplastics (the type found in water bottles and food containers) at room temperature. The engineered bacteria achieved significant PET degradation over 30 days and also worked on other polyester plastics, offering a potential biological solution for cleaning up microplastic pollution in water environments.

2024 The Science of The Total Environment 20 citations
Article Tier 2

Microbial biodegradation of polyethylene terephthalate microplastics by an indigenous Candida tropicalis strain and biocompatibility evaluation of microplastics-degraded metabolites in GIFT Tilapia

Researchers isolated an indigenous Candida tropicalis yeast strain and demonstrated its ability to degrade PET microplastics in batch experiments, measuring degradation through optical density, weight loss, and biofilm formation — and confirming that metabolic byproducts were not toxic to tilapia.

2025 3 Biotech 3 citations
Article Tier 2

Microbial Polyethylene Terephthalate Hydrolases: Current and Future Perspectives

This review surveys microbial enzymes capable of breaking down PET plastic, focusing on the structure and function of key hydrolases like PETase and cutinases. Researchers found that while several enzymes show promising PET-degrading activity, most work slowly and under limited temperature conditions, with engineered variants showing improved performance. The study highlights both the potential and the current limitations of using biological approaches for plastic waste management.

2020 Frontiers in Microbiology 168 citations
Article Tier 2

An archaeal lid-containing feruloyl-esterase degrades polyethylene terephthalate (PET)

This study identified the first archaeal enzyme capable of degrading PET plastic, characterizing its structure and biochemical properties. Expanding the diversity of organisms with PET-degrading enzymes could accelerate the development of biological strategies for breaking down the microplastics contaminating marine and terrestrial environments.

2023
Article Tier 2

Using a marine microalga as a chassis for polyethylene terephthalate (PET) degradation

Researchers genetically engineered a marine microalgae to produce enzymes that break down PET plastic (the kind used in bottles and synthetic fibers), demonstrating for the first time that a saltwater microalgae can be used as a biological platform for PET degradation. This proof-of-concept points toward eco-friendly, ocean-based solutions for tackling plastic pollution at its source.

2019 Microbial Cell Factories 313 citations
Article Tier 2

Degradation of PET plastic with engineered environmental bacteria

Scientists engineered a soil bacterium to break down PET plastic, one of the most common plastics in food packaging and textiles, by giving it the ability to produce and secrete a powerful plastic-degrading enzyme. This is one of the first demonstrations of a living microorganism that can directly consume PET as a food source, which could lead to more sustainable recycling approaches.

2024 4 citations
Article Tier 2

Eco-Microbiology: Discovering Biochemical Enhancers of PET Biodegradation by Piscinibacter sakaiensis

This paper reviews biochemical strategies for enhancing PET biodegradation by microorganisms, focusing on the discovery and engineering of plastic-degrading enzymes. The review highlights recent advances and remaining challenges in scaling up enzymatic plastic degradation for industrial applications.

2024
Article Tier 2

Biodegradation of microplastic by probiotic bifidobacterium

Researchers found that probiotic Bifidobacterium infantis can biodegrade microplastics, demonstrating a novel microbial approach to addressing plastic pollution using a gut-resident bacterium known for regulating intestinal microbiota.

2022 International Journal of Global Warming 24 citations
Article Tier 2

Development and characterization of a bacterial enzyme cascade reaction system for efficient and stable PET degradation

Scientists engineered a bacterial system that displays plastic-degrading enzymes on the cell surface to efficiently break down PET plastic, achieving a 23% degradation rate of microplastics within 7 days. The system uses E. coli bacteria with specially designed protein fibers that both grip and digest PET fragments. This biotechnology approach could eventually help address the growing problem of microplastic pollution in water and soil environments.

2024 Journal of Hazardous Materials 18 citations
Article Tier 2

Biodegradation of highly crystallized poly(ethylene terephthalate) through cell surface codisplay of bacterial PETase and hydrophobin

Researchers engineered yeast cells to display both a PET-degrading enzyme (PETase) and a sticky protein (hydrophobin) on their surface simultaneously, dramatically improving the breakdown of highly crystalline PET plastic — achieving a 329-fold increase in degradation rate compared to the purified enzyme alone. This whole-cell biocatalyst approach could make enzymatic plastic recycling far more practical and efficient.

2022 Nature Communications 126 citations
Article Tier 2

Biodegradation of Poly(Ethylene Terephthalate) Microplastics by Baceterial Communities From Activated Sludge

Scientists isolated bacteria from wastewater treatment sludge that can biodegrade PET plastic, used in plastic bottles and food packaging. The bacteria broke down PET microplastics over a 60-day period, pointing toward a potential biological tool for removing plastic contamination from water treatment systems.

2021
Article Tier 2

Biodegradation of Poly(Ethylene Terephthalate) Microplastics by Baceterial Communities From Activated Sludge

Scientists isolated bacteria from wastewater treatment sludge that can biodegrade PET plastic, used in plastic bottles and food packaging. The bacteria broke down PET microplastics over a 60-day period, pointing toward a potential biological tool for removing plastic contamination from water treatment systems.

2021 1 citations
Article Tier 2

Enhancing PET Degrading Enzymes: A Combinatory Approach

Scientists worked on improving enzymes that can break down PET plastic, one of the most common plastics in consumer products. Using a combinatory approach, researchers enhanced the performance of a naturally occurring PET-degrading enzyme from the bacterium Piscinibacter sakaiensis. The study suggests that engineered enzymes could eventually help create a circular economy for plastic waste by enabling efficient recycling at the molecular level.

2024 ChemBioChem 21 citations
Article Tier 2

Micro-nanoplastics inhibit extracellular polymeric substance and lactate synthesis via perturbing glucose metabolism of Lacticaseibacillus rhamnosus

Researchers found that micro- and nanoplastics — especially nanoscale PET particles — impair the probiotic bacterium Lactobacillus rhamnosus by disrupting central carbon metabolism, reducing its production of lactic acid and protective extracellular polysaccharides, raising concerns that microplastic ingestion could compromise the gut benefits of probiotic bacteria.

2025 Journal of Hazardous Materials
Article Tier 2

Identification of a PET hydrolytic enzyme from the human gut microbiome unveils potential plastic biodegradation in human digestive tract

Researchers discovered a new enzyme in the human gut microbiome that can break down PET plastic, the material used in most drink bottles and food packaging. The enzyme, called HGMP01, was identified through analysis of gut bacterial DNA and confirmed to hydrolyze PET nanoparticles in laboratory tests. The finding suggests that gut bacteria may play an unexpected role in processing the microplastics that humans inevitably ingest through food and beverages.

2024 International Journal of Biological Macromolecules 5 citations
Article Tier 2

Recent trends in microbial and enzymatic plastic degradation: a solution for plastic pollution predicaments

This review covers recent advances in using microorganisms and their enzymes to break down plastics including polyethylene, PVC, polystyrene, and PET, with techniques like protein engineering being used to boost enzyme efficiency. Microbial degradation offers a sustainable approach to reducing the persistent plastic pollution that generates the microplastics found throughout the environment and human body.

2024 Biotechnology for Sustainable Materials 64 citations
Article Tier 2

Degradation of polyethylene terephthalate (PET) plastics by wastewater bacteria engineered via conjugation

Scientists engineered wastewater bacteria to break down PET plastic, one of the most common microplastic types, by transferring plastic-degrading genes through a natural DNA-sharing process. The modified bacteria could partially degrade a consumer PET product in 5 to 7 days. This proof-of-concept approach could help reduce the amount of microplastics released from wastewater treatment plants into the environment.

2024 Microbial Biotechnology 15 citations