Papers

61,005 results
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Article Tier 2

Microplastics and Nanoplastics in Health Concerning Cellular Toxicity Mechanisms, Exposure Pathways, and Global Mitigation Strategies

This review synthesizes current knowledge on how micro- and nanoplastics cause cellular damage in the human body, covering mechanisms like oxidative stress, inflammation, DNA damage, and disruption of cell signaling pathways. Researchers note that exposure occurs through multiple routes including ingestion and inhalation, allowing particles to reach organs throughout the body. The study highlights significant gaps in understanding long-term and low-dose exposure effects that are most relevant to everyday human contact with these particles.

2025 Life 4 citations
Article Tier 2

The Impact of Microplastic on Human Health

This review synthesized evidence on microplastic exposure pathways and health effects in humans, finding that microplastics enter the body via ingestion, inhalation, and dermal contact and are associated with oxidative stress, inflammation, genotoxicity, and endocrine disruption.

2021 Current Biotechnology 5 citations
Article Tier 2

Cellular and Systemic Impacts of Microplastics and Nanoplastics

This review synthesized evidence on how micro- and nanoplastics cause cellular and systemic harm through inflammation, oxidative stress, mitochondrial dysfunction, and endocrine disruption across multiple organ systems. The authors emphasize that exposure is ubiquitous and that health impacts are no longer speculative.

2025 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

Cellular and Systemic Impacts of Microplastics and Nanoplastics

This review systematically examined the cellular and systemic health impacts of micro- and nanoplastics, covering uptake mechanisms, organ distribution, and effects on inflammation, oxidative stress, and endocrine function. The authors conclude that MNPs pose credible risks to multiple body systems and call for stronger regulatory action.

2025 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

Impact of microplastics and nanoplastics on human Health: Emerging evidence and future directions

This review summarizes current evidence on how micro- and nanoplastics enter the human body through food, air, and skin contact, and the cellular damage they may cause. While microplastic pollution is a recognized environmental hazard, the authors note that definitive evidence linking plastic particle exposure to specific health outcomes in humans is still limited and more realistic exposure studies are needed.

2025 Emerging contaminants 11 citations
Article Tier 2

Cellular and Molecular Mechanisms of Micro- and Nanoplastics Driving Adverse Human Health Effects

This review examines the biological mechanisms by which micro- and nanoplastics may cause harm in humans, including oxidative stress, inflammation, disruption of protective barriers, and immune system problems. Evidence from lab and animal studies suggests these particles can affect the gut, heart, brain, and reproductive systems, though human data is still limited to detecting plastics in tissues rather than proving they cause specific diseases. The authors highlight that most studies use higher doses than people actually encounter, making it important to develop research models that better reflect real-world chronic exposure.

2025 Toxics 5 citations
Review Tier 2

A review on microplastics and nanoplastics in the environment: Their occurrence, exposure routes, toxic studies, and potential effects on human health

This review summarizes what is known about how microplastics and nanoplastics enter the human body through food, air, and skin contact, and what they do once inside. Studies on cells and animals show these tiny particles can cause oxidative stress, DNA damage, inflammation, and harm to the immune, digestive, reproductive, and nervous systems. The research makes clear that microplastics are not just an environmental problem but a direct concern for human health.

2022 Marine Pollution Bulletin 379 citations
Article Tier 2

Micro and Nanoplastics on Human Health and Diseases: Perspectives and Recent Advances

This review covers how micro- and nanoplastic particles enter the human body through ingestion, inhalation, infusion, and skin absorption, distribute to virtually all tissues and organs via the circulatory system, and cause health impacts including inflammatory responses, cellular damage, and endocrine disruption.

2025 Preprints.org
Article Tier 2

Cellular and Systemic Effects of Micro- and Nanoplastics in Mammals—What We Know So Far

This review summarized known cellular and systemic effects of micro- and nanoplastics in mammals, finding that while ingestion is common, knowledge of health impacts remains limited, with oxidative stress and inflammation as the most reported biological responses.

2023 Materials 13 citations
Article Tier 2

Human exposure to microplastics: A review on exposure routes and public health impacts

This review examines how microplastics enter the human body through food, air, and skin contact and the health effects they can cause, including oxidative stress, inflammation, hormone disruption, and potential DNA damage. Despite growing evidence of harm, the exact routes plastics take through the body and the cellular mechanisms behind their effects are still not well understood, and there is an urgent need for standardized detection methods.

2024 Journal of Hazardous Materials Advances 37 citations
Article Tier 2

The potential impact of nano- and microplastics on human health: Understanding human health risks.

This review summarizes how nano- and microplastics enter the human body through breathing, eating, drinking, and skin contact, and then accumulate in organs over time. Studies have linked this buildup to respiratory problems like asthma and lung cancer, gut inflammation, disrupted gut bacteria, and neurological symptoms. At the cellular level, plastics cause DNA damage and cell death, though more research is needed to fully understand the long-term health risks in humans.

2024 Environmental Research 331 citations
Article Tier 2

Micro- and Nanoplastics on Human Health and Diseases: Perspectives and Recent Advances

This review provides a comprehensive overview of how micro- and nanoplastics enter the human body through ingestion, inhalation, and skin absorption, and how they can then travel through the bloodstream to reach virtually every organ. Researchers summarize evidence that these particles can trigger inflammation, oxidative stress, and disruption of hormonal and immune functions. The study emphasizes that the ability of these particles to cross biological barriers and accumulate in tissues makes understanding their long-term health effects an urgent research priority.

2025 Microplastics 3 citations
Article Tier 2

Recent insights into uptake, toxicity, and molecular targets of microplastics and nanoplastics relevant to human health impacts

This review summarizes what scientists know about how tiny plastic particles enter the human body and cause harm at the cellular level, including through inflammation, oxidative stress, and disruption of important cell signaling pathways. Americans are estimated to consume tens of thousands to millions of micro- and nanoplastic particles per year, and these particles can penetrate cells and tissues throughout the body.

2023 iScience 193 citations
Review Tier 2

Potential Health Impact of Microplastics: A Review of Environmental Distribution, Human Exposure, and Toxic Effects

This review summarizes existing research on how microplastics are found throughout the environment and in human samples, entering the body through food, air, and skin contact. Lab studies in cells and animals show microplastics can cause oxidative stress, DNA damage, immune reactions, brain toxicity, and reproductive harm, and early human health data links microplastic exposure to several chronic diseases.

2023 Environment & Health 519 citations
Article Tier 2

Recent consequences of micro-nanaoplastics (MNPLs) in subcellular/molecular environmental pollution toxicity on human and animals

This review examines the subcellular and molecular mechanisms by which micro- and nanoplastics cause toxicity in humans and animals, focusing on oxidative stress, inflammation, cell death pathways, and endocrine disruption at the cellular level.

2022 Ecotoxicology and Environmental Safety 27 citations
Article Tier 2

Cytotoxic Effects of Microplastics on Human Cells

This study reviewed and tested the cytotoxic effects of microplastics on human cells, finding that microplastic particles can cause cell damage, inflammation, and oxidative stress at relevant concentrations. The results support growing concern that microplastics ingested or inhaled by humans may pose direct health risks at the cellular level.

2021 DigiNole (Florida State University)
Article Tier 2

Impact of Microplastics and Nanoplastics on Human Health

This review explores how micro- and nanoplastics can enter the human body through the gut, lungs, and skin, and what potential health effects they might cause at the cellular level. While there is growing evidence that these particles trigger toxic responses in cells, research into their specific effects inside the human body is still limited. The paper calls for more studies on how nanoplastics in particular move through human tissue barriers and what long-term damage they may cause.

2021 Nanomaterials 883 citations
Article Tier 2

Research progress on the cellular toxicity caused by microplastics and nanoplastics

This review summarizes current research on how microplastics and nanoplastics cause damage at the cellular level. Researchers identified four main ways these particles harm cells: triggering oxidative stress, damaging cell membranes and organelles, causing inflammation, and disrupting DNA. The findings highlight growing evidence that plastic particles small enough to enter cells can interfere with fundamental biological processes.

2023 Journal of Applied Toxicology 50 citations
Article Tier 2

Understanding the human health impacts of environmental micro- and nanoplastics

This review summarized current understanding of how micro- and nanoplastic particles enter the human body through food and air, accumulate in tissues, and cause health effects through oxidative stress, inflammation, and endocrine disruption, with a focus on gaps in knowledge about long-term human health impacts.

2025 University of Vienna
Article Tier 2

Potential Human Health Impacts of Microplastics and Associated Chemicals

This book chapter reviews human exposure pathways to microplastics — including ingestion, inhalation, and dermal contact — and examines evidence linking tissue-level MP accumulation to inflammation, immune disruption, endocrine effects, and potential carcinogenicity.

2025
Article Tier 2

Microplastics as an Emerging Human Health Risk: Mechanisms, Exposure, and Clinical Evidence

This review examines the growing body of evidence on how microplastics enter the human body through ingestion, inhalation, and skin contact, and have now been detected in blood, lung tissue, placenta, and cardiovascular tissue. Evidence indicates that microplastics may cause harm through oxidative stress, inflammation, and cellular damage, though a direct causal link to specific health conditions has not yet been fully established.

2026 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

Microplastics as an Emerging Human Health Risk: Mechanisms, Exposure, and Clinical Evidence

This review examines the growing body of evidence on how microplastics enter the human body through ingestion, inhalation, and skin contact, and have now been detected in blood, lung tissue, placenta, and cardiovascular tissue. Evidence indicates that microplastics may cause harm through oxidative stress, inflammation, and cellular damage, though a direct causal link to specific health conditions has not yet been fully established.

2026 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

Human exposure to micro- and nanoplastic: biological effects and health consequence

This review summarized the biological effects and health consequences of human exposure to micro- and nanoplastics, covering routes of uptake (ingestion, inhalation, dermal), cellular toxicity mechanisms, and systemic health risks identified in recent experimental and epidemiological studies.

2023 Reviews in Biological and Biomedical Sciences 3 citations
Article Tier 2

Microplastics and human health: unraveling the toxicological pathways and implications for public health

This review pulls together recent research on how microplastics enter the human body and cause cellular damage through inflammation, oxidative stress, and direct cell injury. The authors highlight that microplastics can also amplify the harmful effects of other environmental pollutants they carry, creating combined health risks that are greater than either threat alone.

2025 Frontiers in Public Health 11 citations