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Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Environmental Sources Gut & Microbiome Human Health Effects Marine & Wildlife Nanoplastics Remediation Sign in to save

Impact of Microplastics and Nanoplastics on Human Health

Nanomaterials 2021 883 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 65 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Maxine Swee‐Li Yee, Ling‐Wei Hii, Chin-King Looi, Wei‐Meng Lim, Shew Fung Wong, Yih-Yih Kok, Boon-Keat Tan, Chiew-Yen Wong, Chee‐Onn Leong

Summary

This review explores how micro- and nanoplastics can enter the human body through the gut, lungs, and skin, and what potential health effects they might cause at the cellular level. While there is growing evidence that these particles trigger toxic responses in cells, research into their specific effects inside the human body is still limited. The paper calls for more studies on how nanoplastics in particular move through human tissue barriers and what long-term damage they may cause.

Plastics have enormous impacts to every aspect of daily life including technology, medicine and treatments, and domestic appliances. Most of the used plastics are thrown away by consumers after a single use, which has become a huge environmental problem as they will end up in landfill, oceans and other waterways. These plastics are discarded in vast numbers each day, and the breaking down of the plastics from micro- to nano-sizes has led to worries about how toxic these plastics are to the environment and humans. While, there are several earlier studies reported the effects of micro- and nano-plastics have on the environment, there is scant research into their impact on the human body at subcellular or molecular levels. In particular, the potential of how nano-plastics move through the gut, lungs and skin epithelia in causing systemic exposure has not been examined thoroughly. This review explores thoroughly on how nanoplastics are created, how they behave/breakdown within the environment, levels of toxicity and pollution of these nanoplastics, and the possible health impacts on humans, as well as suggestions for additional research. This paper aims to inspire future studies into core elements of micro- and nano-plastics, the biological reactions caused by their specific and unusual qualities.

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