Papers

61,005 results
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Article Tier 2

Toxicity effects of Ciprofloxacin on biochemical parameters, histological characteristics, and behaviors of Corbicula fluminea in different substrates

Researchers found that the antibiotic ciprofloxacin in river sediments caused liver damage, immune suppression, and behavioral changes in freshwater clams. This shows that sediment-associated pharmaceutical pollutants—which often co-occur with microplastics in riverbed sediments—can harm important filter-feeding organisms.

2021 Research Square (Research Square)
Article Tier 2

The Effect of the Antidepressant Citalopram on the Bioconcentration and Biomarker Response of Daphnia magna at Environmentally Relevant Concentrations

Researchers studied how the common antidepressant citalopram affects the water flea Daphnia magna at concentrations typically found in the environment. They found that even very low doses altered the organism's energy metabolism, behavior, and antioxidant defenses, with the drug accumulating in the organisms at hundreds of times the surrounding water concentration. While focused on pharmaceutical pollution rather than microplastics, the study illustrates how trace contaminants in waterways can have outsized biological effects on aquatic life.

2025 Toxics 3 citations
Article Tier 2

Microplastics and movement- exploring behavioural toxicity in Daphnia

Researchers explored behavioral toxicity endpoints for microplastic exposure in Daphnia, expanding beyond standard lethality and immobilization tests to include movement parameters as sensitive indicators of sublethal effects. Microplastic exposure altered swimming behavior in Daphnia at concentrations that did not cause visible mortality, demonstrating that behavioral assays detect impacts missed by conventional endpoints.

2024 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

Unveiling the multilevel impact of four water-soluble polymers on Daphnia magna: From proteome to behaviour (a case study)

This study investigated the effects of four common water-soluble polymers, including polyvinyl alcohol and polyethylene glycol, on the freshwater organism Daphnia magna. Researchers found that these widely used industrial chemicals can affect the organisms at multiple biological levels, from protein expression changes to altered swimming behavior, indicating that water-soluble polymers deserve more attention as aquatic pollutants.

2024 Journal of Hazardous Materials 8 citations
Article Tier 2

Pathophysiological impact of chronic exposure of ciprofloxacin antibiotic residue above the MRL level in mice

Researchers chronically exposed organisms to ciprofloxacin antibiotic residues at environmentally relevant concentrations, measuring physiological and pathological responses. Ciprofloxacin exposure caused oxidative stress, tissue damage, and dysregulation of immune markers, suggesting that sub-therapeutic antibiotic concentrations common in polluted water pose meaningful health risks to aquatic organisms.

2024
Article Tier 2

Vertical distribution of microplastics in water bodies causes sublethal effects and changes in Daphnia magna swimming behaviour

Researchers found that sinking microplastics caused sublethal effects in Daphnia magna, reducing swimming velocity and altering behavior, with vertical distribution in the water column posing risks to both pelagic and benthic filter feeders.

2021 Ecotoxicology and Environmental Safety 36 citations
Article Tier 2

Daphnia magna responses to fish kairomone and chlorpromazine exposures

Researchers exposed the freshwater crustacean Daphnia magna to predator chemical cues (fish kairomones) and the neuroactive pharmaceutical chlorpromazine, finding that predator cues dominated behavioral and reproductive responses while the drug combination altered oxygen consumption, raising concerns about pharmaceutical interference with antipredator adaptations.

2020 Chemico-Biological Interactions 25 citations
Article Tier 2

Microplastics and movement- exploring behavioural toxicity in Daphnia

Researchers investigated the behavioral toxicity of microplastics on Daphnia, moving beyond standard mortality and immobilization endpoints to capture subtler effects on movement. The study found that microplastic exposure alters locomotion in ways that standard tests would miss.

2024 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

Combined effects of microplastics and antibiotic-resistant bacteria on Daphnia magna growth and expression of functional genes

Researchers tested the combined effects of microplastics and antibiotic-resistant bacteria on tiny freshwater organisms called Daphnia magna. They found that polystyrene microplastics colonized with resistant Shigella bacteria were ingested and trapped in the organisms' intestines, causing changes in body size, reproduction, and gene expression. The study suggests that microplastics carrying antibiotic-resistant bacteria may pose amplified ecological risks to aquatic food chains.

2023 The Science of The Total Environment 20 citations
Article Tier 2

ПАРАМЕТРЫ ПЛАВАТЕЛЬНОГО ПОВЕДЕНИЯ ДАФНИЙ КАК ИНДИКАТОРЫ ТОКСИЧНОСТИ СРЕДЫ

This review examines scientific publications on the swimming behavior parameters and patterns of Daphnia organisms used as ecotoxicological indicators of aquatic pollution, covering both organic and inorganic contaminants. The analysis reveals a large and growing body of research demonstrating the sensitivity and diversity of behavioral testing methods based on Daphnia swimming pattern assessment.

2024 Российский журнал прикладной экологии
Article Tier 2

Ingestion and impacts of water-borne polypropylene microplastics on Daphnia similis

Researchers found that acute exposure to polypropylene microplastics caused immobility in Daphnia similis, increased reactive oxygen species production, elevated antioxidant enzyme activity, and decreased neurotransmitter function.

2022 Environmental Science and Pollution Research 38 citations
Article Tier 2

The Effects of Polyethylene and Polypropylene Microplastics on Daphnia dentifera

Researchers examined the effects of polyethylene and polypropylene microplastics on the body size, swim speed, and clonal growth rate of the freshwater crustacean Daphnia dentifera, assessing sublethal physiological and behavioural impacts of two common plastic polymer types.

2025 SPARK Scholarship at Parkland (Parkland College)
Article Tier 2

The effect of microplastics on the speed, mortality rate, and swimming patterns of Daphnia Magna

This study compared how polystyrene and polyethylene microplastics affect the swimming speed, mortality, and movement patterns of Daphnia magna water fleas, finding both plastics caused behavioral changes. Daphnia are key animals in freshwater food webs, and microplastic-induced behavioral impairment could affect their role in aquatic ecosystems.

2021 Journal of Emerging Investigators 2 citations
Article Tier 2

Effects of microplastics on key reproductive and biochemical endpoints of the freshwater microcrustacean Daphnia magna

Researchers studied how microplastics affect reproduction and biochemistry in the freshwater water flea Daphnia magna, a widely used indicator species. They found that microplastic exposure led to changes in reproductive output and altered key biochemical markers in these small crustaceans. The study suggests that even tiny plastic particles can disrupt important biological functions in freshwater organisms that form the base of aquatic food webs.

2024 Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology 5 citations
Article Tier 2

Cefotaxime Exposure-Caused Oxidative Stress, Intestinal Damage and Gut Microbial Disruption in Artemia sinica

Researchers examined the toxic effects of the antibiotic cefotaxime on Artemia sinica, a small aquatic invertebrate. The study found that cefotaxime exposure caused oxidative stress, intestinal damage, and disruption of gut microbial communities in a dose-dependent manner.

2024 Microorganisms 3 citations
Article Tier 2

Effect of chlorpyrifos on freshwater microbial community and metabolic capacity of zebrafish

Researchers exposed zebrafish and their surrounding water to chlorpyrifos, a widely used pesticide, and found it disrupted the diversity of aquatic microbes, increased dangerous antibiotic-resistant bacteria, and altered the gut metabolism of fish — raising concerns about the ecological and food-safety risks of pesticide runoff into waterways.

2023 Ecotoxicology and Environmental Safety 15 citations
Article Tier 2

Laterally biased diffusion of males of the water flea Daphnia magna

This study examined the swimming behavior of male Daphnia magna water fleas, finding they show directional swimming biases. Daphnia are standard test organisms for microplastic toxicity research, and understanding their natural behavior helps interpret results from ecotoxicology experiments.

2021
Article Tier 2

The Physiological and Biochemical Responses of Daphnia magna to Dewatered Drinking Water Treatment Residue

This study examined the physiological and biochemical responses of Daphnia magna to dewatered drinking water treatment residue, finding signs of chronic toxicity in this common freshwater zooplankton. Drinking water treatment byproducts can contain co-contaminants including microplastics that may contribute to the toxicity observed in aquatic test organisms.

2020 International Journal of Environmental Research and Public Health 10 citations
Article Tier 2

Combined Effects of Polystyrene Nanoplastics and Enrofloxacin on the Life Histories and Gut Microbiota of Daphnia magna

Researchers exposed Daphnia magna to polystyrene nanoplastics and the antibiotic enrofloxacin alone and in combination, measuring life history traits and gut microbiota responses. Both stressors individually reduced survival and reproduction, and combined exposure altered the taxonomic composition and metabolic function of gut microbiota more than either contaminant alone.

2022 Water 19 citations
Article Tier 2

An In Vivo Whole-Transcriptomic Approach to Assess Developmental and Reproductive Impairments Caused by Flumequine in Daphnia magna

Researchers used whole-transcriptomic analysis to assess how the antibiotic flumequine causes developmental and reproductive impairments in Daphnia magna, identifying disrupted pathways related to molting, reproduction, and oxidative stress response.

2023 International Journal of Molecular Sciences 9 citations
Article Tier 2

Beyond microplastics: Water soluble synthetic polymers exert sublethal adverse effects in the freshwater cladoceran Daphnia magna

Researchers exposed the freshwater cladoceran Daphnia magna to five water-soluble synthetic polymers commonly used as industrial flocculants and coagulants, finding sublethal life history changes and elevated reactive oxygen species levels without acute mortality. Because daphnids are keystone species controlling phytoplankton biomass, these sublethal effects could produce cascading trophic consequences, highlighting water-soluble polymers as a neglected class of aquatic contaminants.

2022 Zenodo (CERN European Organization for Nuclear Research)
Meta Analysis Tier 1

The effect of microplastics on Daphnia fitness – systematic review and meta-analysis.

This systematic review and meta-analysis examines how micro and nanoplastic particles affect the health and reproduction of Daphnia, a tiny freshwater organism commonly used as an indicator of water quality. The findings matter because Daphnia sit at the base of many aquatic food chains, so harm to these organisms from plastic pollution can ripple upward through ecosystems and ultimately affect the fish and water we depend on.

2023
Systematic Review Tier 1

The effect of microplastics on Daphnia fitness – Systematic review and meta‐analysis

This systematic review and meta-analysis examines how micro- and nanoplastics affect the health and reproduction of Daphnia, a key freshwater organism used in toxicity testing. The findings confirm that plastic particles can harm these organisms, which is significant because Daphnia are a foundational species in freshwater ecosystems connected to human water supplies.

2024 Freshwater Biology 9 citations
Article Tier 2

Ecological risks of combination of multiple pollutants at environmentally relevant concentrations: Insights from the changes in life history traits, gut microbiota, and transcriptomic responses in Daphnia magna

Researchers exposed Daphnia magna to a combination of 11 pollutants including microplastics, antibiotics, and heavy metals at environmentally relevant ng/L–μg/L concentrations and found significant reductions in heart rate, reproduction, and lifespan, plus gut microbiota and transcriptomic changes — effects that single-pollutant studies would not predict.

2025 Resources Environment and Sustainability