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61,005 resultsShowing papers similar to The Rising Threat: Nano and Microplastics Infiltration in Urinary and Reproductive Systems
ClearMicroplastics and human fertility: A comprehensive review of their presence in human samples and reproductive implication
This review examines the growing evidence linking microplastic and nanoplastic exposure to potential effects on human fertility. Researchers noted that these tiny plastic particles have been detected in blood, placenta, and seminal fluid, suggesting continuous systemic exposure and the ability to cross key biological barriers. Animal studies indicate that microplastics may affect reproductive health through oxidative stress, hormonal disruption, and tissue damage, though more standardized human research is needed.
Unraveling the threat: Microplastics and nano-plastics' impact on reproductive viability across ecosystems
This review summarizes research on how microplastics and nanoplastics affect reproduction across many species, from aquatic invertebrates to mammals including humans. In males, exposure leads to testicular damage, lower sperm quality, and hormone disruption; in females, it causes ovarian and uterine problems, inflammation, and reduced fertility. The evidence also shows these reproductive harms can be passed to offspring, raising serious concerns about long-term effects on human fertility.
Adverse effects of microplastics and nanoplastics on the reproductive system: A comprehensive review of fertility and potential harmful interactions
This review summarizes how microplastics and nanoplastics can harm both male and female reproductive systems by disrupting hormone signaling, damaging sperm and egg cells, and causing inflammation in reproductive tissues. Smaller nanoplastics are especially concerning because they can cross biological barriers more easily and reach the testes and ovaries. With global infertility rates rising, the authors highlight environmental plastic exposure as a factor that deserves more research attention.
"Unseen Dangers: The Effects of Micro- and Nanoplastics on Human Reproductive Health - A Narrative Review"
This review examines the effects of micro- and nanoplastics on human reproductive health, covering evidence from in vitro, animal, and epidemiological studies showing that plastic particles can disrupt hormone signaling, sperm function, ovarian development, and placental integrity.
The Microplastics and Human Health: Focus on the Reproductive System
This review examined evidence that microplastics accumulate in human reproductive tissues and evaluated their potential effects on fertility and reproductive health. The authors found microplastics detected in testes, ovaries, placenta, and semen, and summarized mechanistic evidence linking them to hormonal disruption, oxidative stress, and impaired gamete function.
Polyethylene andPolyvinyl Chloride Nanoplastics inHuman Follicular Fluid and Seminal Plasma: Impact on Fertilizationand Sperm Quality
Researchers used pyrolysis GC/MS to detect polyethylene (PE) and polyvinyl chloride (PVC) nanoplastics in follicular fluid and seminal plasma from 51 IVF couples. Both polymers were present in both reproductive fluids, and while associations with fertilization outcomes were not statistically significant, the detection of nanoplastics in human reproductive fluids represents a novel concerning finding.
Toxicological effects of micro/nano-plastics on human reproductive health: A review
This review summarizes research on how micro- and nanoplastics affect human reproductive health in both men and women. Evidence from animal and lab studies shows that these particles can accumulate in reproductive organs, disrupt hormones, damage eggs and sperm, and cause inflammation and oxidative stress. While human studies are still limited, the growing body of evidence suggests that microplastic exposure is a potential threat to fertility that warrants further investigation.
Effects of nano and microplastics on the reproduction system: In vitro and in vivo studies review
This review summarizes both lab and animal studies on how micro and nanoplastics affect the reproductive system in males and females. Evidence shows that microplastics can reduce sperm quality, damage ovaries, disrupt hormone levels, and even cross the placenta during pregnancy. The findings raise significant concerns about how widespread microplastic exposure might contribute to fertility problems and reproductive health issues in humans.
Polyethylene and Polyvinyl Chloride Nanoplastics in Human Follicular Fluid and Seminal Plasma: Impact on Fertilization and Sperm Quality
Researchers detected polyethylene and PVC nanoplastics in both the follicular fluid and seminal plasma of 51 couples undergoing IVF treatment. Higher levels of PVC nanoplastics in seminal plasma were associated with lower sperm concentration and fewer high-quality embryos, while nanoplastics in follicular fluid showed no significant effect on fertilization rates. This is among the first studies to directly measure nanoplastics in human reproductive fluids and link them to reduced fertility outcomes.
Effects of micro(nano)plastics on the reproductive system: A review
This review summarizes research on how micro and nanoplastics affect the reproductive system in both animal studies and cell experiments. Evidence indicates these particles can cross biological barriers, accumulate in reproductive organs, and disrupt hormones, egg development, and sperm quality. While human studies are still limited, the animal data suggests microplastic exposure may be a meaningful concern for reproductive health.
Microplastic Contaminationof Human Sperm before InVitro Fertilization Warrants Attention for Early Life Exposure Risks
Researchers investigated whether medical plasticware used in IVF procedures contaminates human sperm with microplastics, raising concerns about direct reproductive cell exposure to microplastics released during sperm extraction and handling.
Reproductive and developmental implications of micro- and nanoplastic internalization: Recent advances and perspectives
This systematic review documented the detection of micro- and nanoplastics in human semen, placenta, and ovarian follicular fluid, and found evidence linking exposure to impaired sperm quality, disrupted ovarian function, and adverse pregnancy outcomes. In animal models, MNPs caused developmental toxicity and transgenerational effects, with oxidative stress, inflammation, and epigenetic modification identified as key mechanisms.
Exposure to microplastics and human reproductive outcomes: A systematic review
This systematic review examined evidence linking microplastic exposure to reproductive health problems in humans. While early findings raise concerns, the review emphasizes that more high-quality studies are needed to clearly establish how microplastics affect fertility and reproduction.
Exposure to micro- and nanoplastics and human reproductive outcomes: a systematic review
This systematic review summarizes existing research on whether micro and nanoplastics affect human fertility and pregnancy outcomes. While the evidence is still emerging, the review found that these particles have been detected in placenta and fetal tissue, raising important questions about potential effects on reproductive health that warrant further study.
Plastic pollution in human reproduction: should we worry?
Researchers reviewed evidence that micro- and nanoplastics can cross the placenta, enter amniotic fluid, and accumulate in reproductive tissues in both men and women. Animal and cell studies suggest these particles may reduce egg and sperm quality and harm fetal development, though most experiments use higher doses than people realistically encounter.
First evidence of microplastics in human ovarian follicular fluid: an emerging threat to female fertility
In the first study of its kind, researchers detected microplastics in the ovarian follicular fluid of 14 out of 18 women undergoing fertility treatment, with an average of about 2,191 particles per milliliter. A significant correlation was found between microplastic concentration and FSH hormone levels, suggesting a possible link to reproductive function. This groundbreaking finding provides direct evidence that microplastics can reach human reproductive organs and may pose a threat to female fertility.
Human reproductive exposure to microplastics: A multi-technique analytical study of menstrual and amniotic fluids
Scientists found tiny plastic particles called microplastics in menstrual blood and amniotic fluid (the fluid that surrounds babies in the womb) for the first time. These plastic pieces came from common materials like water bottles and food packaging, showing that plastic pollution is reaching deep into our reproductive systems. While we don't yet know what health effects this might cause, the discovery raises important questions about how widespread plastic contamination could affect pregnancy and reproductive health.
Detection and characterization of microplastics in the human testis and semen
Researchers detected microplastics in both human testis tissue and semen samples for the first time, finding an average of about 12 particles per gram in testis and different plastic types in semen. Polystyrene dominated in testis while polyethylene and PVC were most common in semen, providing critical evidence that microplastics can pollute the male reproductive system and raising concerns about potential fertility impacts.
The Invisible Intruder: a Review of Microplastics Accumulation in Human Tissues and Implications for Public Health, with Emphasis on Reproductive Health
This review synthesizes biomonitoring studies on microplastic and nanoplastic accumulation in human tissues, with particular emphasis on reproductive health effects. Researchers found these particles have been detected in blood, lungs, placentas, breast milk, testes, and brain tissue, raising questions about potential long-term implications for human health and reproduction.
Atlas and source of the microplastics of male reproductive system in human and mice
Researchers mapped microplastic contamination throughout the male reproductive system in both humans and mice, finding plastics in the testes, epididymis, seminal vesicles, and prostate. The study suggests that microplastics found in semen likely originate from these reproductive organs rather than from external contamination. A lifestyle questionnaire revealed that living in urban areas, eating home-cooked meals, and using scrub cleansers were significant sources of microplastic exposure in men.
Micro/nano plastics in the urinary system: Pathways, mechanisms, and health risks.
This review synthesizes emerging evidence on how micro- and nano-plastics reach the urinary system, accumulate in kidney and bladder tissue, and cause damage through oxidative stress, inflammation, and disruption of cellular function. The authors conclude that the urinary system is a primary site of microplastic accumulation and call for more research on long-term health impacts.
Review of microplastics fate in humans with a focus on the urinary system
This review synthesized current knowledge on microplastic fate in the human body, with a particular focus on the urinary system as an excretion pathway. Evidence suggests microplastics can reach the kidneys and urinary tract, raising questions about chronic exposure effects on urinary function.
Targeting Modifiable Risks: Molecular Mechanisms and Population Burden of Lifestyle Factors on Male Genitourinary Health
This systematic review examines how lifestyle factors, including microplastic exposure, affect male reproductive health. Research shows that microplastics, along with other environmental contaminants, may contribute to declining sperm quality and male infertility, which now affects up to 50% of infertility cases worldwide.
Microplastics and Fertility
This paper reviews the growing body of evidence linking microplastic exposure to impaired human fertility, covering how microplastics and associated chemical additives can disrupt reproductive hormones and damage sperm and egg quality. It highlights the need for further research to establish dose-response relationships.