Papers

61,005 results
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Article Tier 2

Dietary Artemisia arborescens Supplementation Effects on Growth, Oxidative Status, and Immunity of Gilthead Seabream (Sparus aurata L.)

Researchers tested whether adding dried Artemisia arborescens plant material to fish feed could improve the health and immune response of gilthead seabream. They found that the plant supplement enhanced antioxidant capacity and boosted immune markers in the fish without negatively affecting growth. The study suggests that medicinal plant supplements in aquaculture feed could offer a sustainable alternative to antibiotics for maintaining fish health.

2024 Animals 4 citations
Article Tier 2

Protective Effects of Curcumin and/or Ginger Supplementation against Oreochromis niloticus Oxidative Stress Induced by Ultraviolet-A Radiation

Researchers found that dietary supplementation with curcumin and/or ginger significantly protected Nile tilapia from oxidative stress induced by ultraviolet-A radiation, improving antioxidant enzyme activity and reducing DNA fragmentation and lipid peroxidation. The findings suggest these natural compounds can serve as effective antioxidant feed additives in aquaculture.

2023 Egyptian Journal of Aquatic Biology and Fisheries 2 citations
Article Tier 2

Effect of silk fibroin microparticles on cellular immunity and liver of gilthead seabream (Sparus aurata L.) with and without experimental skin injuries

Researchers fed silk fibroin microparticles to gilthead seabream with and without experimental skin wounds, finding effects on cellular immunity and liver function, with implications for the use of microparticles in aquaculture health management.

2024 Journal of Animal Physiology and Animal Nutrition 1 citations
Article Tier 2

Astaxanthin: a powerful antioxidant used in aquaculture for coloration with aquatic animal health implications

Not relevant to microplastics — this review covers astaxanthin, a natural antioxidant pigment used in aquaculture, and its potential health benefits for farmed fish and crustaceans.

2023 Journal of Animal Science and Animal Nutrition 2 citations
Article Tier 2

Supplementary Feed Potential on Histology and Immune Response of Tilapia (Oreochromis niloticus L.) Exposed to Microplastics

Researchers found that supplementing tilapia feed with probiotics or vitamin C significantly mitigated microplastic-induced organ damage, reducing liver necrosis and inflammation markers while improving intestinal structure and immune cytokine balance.

2023 Sains Malaysiana 9 citations
Article Tier 2

The Effects of Probiotics on the Recovery of Growth, Digestive, Antioxidant, Immune Functions, and Gut Microbiota of Chinese Hooksnout Carp (Opsariichthys bidens) Under Microplastic Stress

Researchers exposed juvenile Chinese hooksnout carp to polystyrene microplastics for seven days, then administered Bacillus coagulans probiotics at three doses for 56 days and found that medium and high probiotic doses significantly improved growth, digestive enzyme activity, antioxidant function, and gut microbiota recovery.

2025 Fishes
Clinical Trial Tier 1

Curcumin Mitigates Microplastic-Induced Damage in Livestock and Poultry: Mechanistic Insights and Strategies for Sustainable Farming

This review examines how curcumin, a natural compound from turmeric, can protect livestock and poultry from microplastic-induced damage. The research shows that curcumin activates antioxidant defenses and reduces inflammation caused by microplastic exposure in animals, suggesting that natural dietary supplements may offer a strategy for mitigating some health effects of plastic contamination.

2025 Veterinary Sciences 1 citations
Article Tier 2

Mitigating Dietary Microplastic Accumulation and Oxidative Stress Response in European Seabass (Dicentrarchus labrax) Juveniles Using a Natural Microencapsulated Antioxidant

In a study with European seabass, researchers found that microplastics in fish feed were absorbed through the gut and accumulated in the liver, triggering oxidative stress. However, when the fish were also given microencapsulated natural astaxanthin (an antioxidant), it reduced both the stress response and the amount of microplastics absorbed by clumping the particles together in the gut. This suggests that certain natural compounds might help reduce the harmful effects of dietary microplastic exposure.

2024 Antioxidants 14 citations
Article Tier 2

Impact of polystyrene microplastic exposure on gilthead seabream (Sparus aurata Linnaeus, 1758): Differential inflammatory and immune response between anterior and posterior intestine

Researchers fed gilthead seabream polystyrene microplastics for 21 days and found they triggered inflammation and immune disruption in both sections of the intestine, with the rear portion more severely affected. The microplastics activated inflammatory signaling pathways and weakened the gut barrier by reducing tight junction proteins. The findings suggest microplastic ingestion could compromise gut health and immune function in fish.

2023 The Science of The Total Environment 40 citations
Article Tier 2

Microplastic ingestion in reared aquaculture fish: Biological responses to low-density polyethylene controlled diets in Sparus aurata

Researchers fed gilthead seabream fish diets enriched with virgin and weathered polyethylene microplastics for three months, followed by one month of clean feeding. Microplastic ingestion increased over time, with weathered particles accumulating more, but all particles were fully cleared from the digestive tract after the detoxification period. The study found no long-term effects on fish growth or body condition, suggesting that this species does not retain ingested microplastics in its digestive system over time.

2021 Environmental Pollution 53 citations
Article Tier 2

Nanoplastics impair the intestinal health of the juvenile large yellow croaker Larimichthys crocea

Researchers exposed juvenile large yellow croaker fish to nano-sized polystyrene particles to assess impacts on intestinal health and growth. The study found that nanoplastics accumulated in the fish and caused disorders in digestion, antioxidant defenses, immune function, and intestinal microflora, indicating that nanoplastics can significantly impair gut health in commercially important marine fish species.

2020 Journal of Hazardous Materials 190 citations
Review Tier 2

Histomorphological Changes in Fish Gut in Response to Prebiotics and Probiotics Treatment to Improve Their Health Status: A Review

This review summarizes how prebiotics and probiotics, beneficial supplements added to fish feed, can improve gut health and disease resistance in farmed fish. A healthy gut microbiome is critical for nutrient absorption and immune defense in fish. While not directly about microplastics, the research is relevant because microplastics are known to disrupt gut bacteria in aquatic organisms, and probiotics may help counteract some of those effects.

2023 Animals 71 citations
Article Tier 2

Effect of Probiotic Supplimentations on the Gut Histoarchitecture of Stinging Catfish, Heteropneustes fossilis

This aquaculture study evaluated the effects of probiotic supplementation on gut histology in stinging catfish, finding that probiotics improved intestinal morphology—relevant to understanding how gut health modifications may influence susceptibility to microplastic-induced gastrointestinal damage.

2025 European Journal of Aquatic Sciences
Article Tier 2

Mitigation of Dietary Microplastic Accumulation and Oxidative Stress Response in Rainbow Trout (Oncorhynchus mykiss) Fry Through Dietary Supplementation of a Natural Microencapsulated Antioxidant

Researchers tested whether a microencapsulated natural antioxidant, astaxanthin, could protect rainbow trout fry from the harmful effects of dietary microplastics over a 60-day feeding trial. The antioxidant supplement reduced microplastic accumulation in fish tissues and helped counteract oxidative stress caused by the plastic particles. The findings suggest that dietary interventions could help mitigate microplastic harm in farmed fish, with potential implications for aquaculture safety.

2025 Animals 2 citations
Article Tier 2

Natural-based solutions to mitigate dietary microplastics side effects in fish

Zebrafish reared for 6 months on diets containing microencapsulated astaxanthin and microplastics showed reduced oxidative stress and lower MP accumulation in liver compared to controls, suggesting antioxidant supplementation can mitigate the toxicological effects of dietary microplastic exposure.

2024 Chemosphere 5 citations
Article Tier 2

Long-term exposure to microplastics induces oxidative stress and a pro-inflammatory response in the gut of Sparus aurata Linnaeus, 1758

Researchers fed gilthead seabream a diet containing low-density polyethylene microplastics for 90 days and found progressive increases in oxidative stress biomarkers, inflammatory enzyme activity, and tissue damage in the gut. After a 30-day depuration period, most biomarker values returned toward normal levels, indicating some recovery capacity. The study demonstrates that long-term microplastic ingestion can induce sustained oxidative stress and inflammation in fish intestines.

2020 Environmental Pollution 203 citations
Article Tier 2

Effect of microplastic particles on the gills structure of freshwater fish supplemented with probiotics and vitamin C

This study tested whether commercial feed supplemented with probiotics and vitamin C could repair gill tissue damage in Nile tilapia (Oreochromis niloticus) caused by microplastic particle exposure. Both supplements showed protective effects on gill histology, suggesting dietary interventions may partially mitigate microplastic-induced tissue damage in farmed fish.

2023 IOP Conference Series Earth and Environmental Science 3 citations
Article Tier 2

Micro-algal astaxanthin ameliorates polystyrene microplastics-triggered necroptosis and inflammation by mediating mitochondrial Ca2+ homeostasis in carp’s head kidney lymphocytes (Cyprinus carpio L.)

Researchers investigated whether astaxanthin, a natural pigment from microalgae, could protect carp immune cells from damage caused by polystyrene microplastics. They found that astaxanthin reduced inflammation and cell death triggered by microplastics by helping maintain calcium balance within the cells' mitochondria. The study suggests that natural antioxidant compounds may help mitigate some of the harmful immune effects of microplastic exposure in fish.

2023 Fish & Shellfish Immunology 18 citations
Clinical Trial Tier 1

Effect of dietary cinnamon supplementation on the growth in length, haematology, serum biochemistry, intestinal microbiota and enzymes and histomorphological changes of the intestine, liver and the kidney of Heteroclarias (Clarias gariepinus ♀ × Heterobra ♂)

Dietary cinnamon supplementation at 1-2% significantly improved growth, blood parameters, antioxidant enzyme activity, and intestinal health in juvenile catfish over a 56-day trial. The spice enhanced beneficial gut microbiota while reducing pathogenic bacteria, suggesting cinnamon as a natural feed additive for aquaculture.

2023 Veterinary Integrative Sciences
Article Tier 2

Potential of feed supplements on morphometric and gonad weight of fish exposed to microplastics

Researchers investigated whether probiotic supplements from lactic acid bacteria and Vitamin C could mitigate the effects of microplastic exposure on the morphometric measurements and gonad weight of tilapia, finding that feed supplementation supported recovery in fish exposed to microplastic-contaminated diets.

2022 IOP Conference Series Earth and Environmental Science 2 citations
Article Tier 2

Size and concentration effects of microplastics on digestion and immunity of hybrid snakehead in developmental stages

Researchers examined how microplastic size and concentration affect digestion and immunity in hybrid snakehead fish at different developmental stages, finding that larvae were more sensitive to small, high-concentration microplastics while juveniles mounted immune and antioxidant defense responses.

2021 Aquaculture Reports 46 citations
Article Tier 2

Role of dietary Schizochytrium sp. in improving disease resistance of zebrafish through metabolic and microbial analysis

Researchers found that substituting fish oil with marine microalgae Schizochytrium sp. in zebrafish diets improved disease resistance by altering gut microbiota and immune-related metabolic pathways. This is a fish nutrition and immunology study not directly related to environmental microplastics.

2020 Research Square (Research Square) 3 citations
Article Tier 2

The key issue to larval health research in Dover sole Solea solea L. : a reliable experimental set-up and challenge model, as exemplified by assessing the protective potential of probiotic candidates

This study addressed the challenge of reliably raising Dover sole larvae for aquaculture, finding that a stable larval diet and controlled conditions significantly improved growth and survival. Robust aquaculture production methods are important context for understanding how farmed fish — including those exposed to microplastics in their environment — develop and grow.

2017 Ghent University Academic Bibliography (Ghent University)
Article Tier 2

Dietary silymarin, Silybum marianum extract ameliorates cadmium chloride toxicity in common carp, Cyprinus carpio

Supplementing the diet of common carp with silymarin extract protected fish from cadmium chloride toxicity, with treated fish showing reduced liver damage, lower oxidative stress markers, and better growth performance compared to cadmium-exposed controls without the supplement.

2021 Annals of Animal Science 17 citations