Papers

20 results
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Article Tier 2

Astaxanthin: a powerful antioxidant used in aquaculture for coloration with aquatic animal health implications

Not relevant to microplastics — this review covers astaxanthin, a natural antioxidant pigment used in aquaculture, and its potential health benefits for farmed fish and crustaceans.

2023 Journal of Animal Science and Animal Nutrition 2 citations
Article Tier 2

Natural-based solutions to mitigate dietary microplastics side effects in fish

Zebrafish reared for 6 months on diets containing microencapsulated astaxanthin and microplastics showed reduced oxidative stress and lower MP accumulation in liver compared to controls, suggesting antioxidant supplementation can mitigate the toxicological effects of dietary microplastic exposure.

2024 Chemosphere 5 citations
Article Tier 2

Mitigation of Dietary Microplastic Accumulation and Oxidative Stress Response in Rainbow Trout (Oncorhynchus mykiss) Fry Through Dietary Supplementation of a Natural Microencapsulated Antioxidant

Researchers tested whether a microencapsulated natural antioxidant, astaxanthin, could protect rainbow trout fry from the harmful effects of dietary microplastics over a 60-day feeding trial. The antioxidant supplement reduced microplastic accumulation in fish tissues and helped counteract oxidative stress caused by the plastic particles. The findings suggest that dietary interventions could help mitigate microplastic harm in farmed fish, with potential implications for aquaculture safety.

2025 Animals 2 citations
Article Tier 2

Captivating Colors, Crucial Roles: Astaxanthin’s Antioxidant Impact on Fish Oxidative Stress and Reproductive Performance

This review examines how the antioxidant astaxanthin can protect fish from oxidative stress and improve their reproductive health in aquaculture settings. While not directly about microplastics, the research is relevant because microplastic exposure causes oxidative stress in fish, and antioxidants like astaxanthin could help mitigate that damage. Understanding these protective mechanisms may be important for maintaining the health and safety of farmed fish destined for human consumption.

2023 Animals 50 citations
Article Tier 2

Mitigating Dietary Microplastic Accumulation and Oxidative Stress Response in European Seabass (Dicentrarchus labrax) Juveniles Using a Natural Microencapsulated Antioxidant

In a study with European seabass, researchers found that microplastics in fish feed were absorbed through the gut and accumulated in the liver, triggering oxidative stress. However, when the fish were also given microencapsulated natural astaxanthin (an antioxidant), it reduced both the stress response and the amount of microplastics absorbed by clumping the particles together in the gut. This suggests that certain natural compounds might help reduce the harmful effects of dietary microplastic exposure.

2024 Antioxidants 14 citations
Article Tier 2

Protective efficacy of dietary natural antioxidants on microplastic particles-induced histopathological lesions in African catfish (Clarias gariepinus)

Researchers tested whether dietary natural antioxidants could protect African catfish from tissue damage caused by microplastic ingestion. Fish fed microplastics alone showed significant kidney, liver, and intestinal damage including cellular necrosis and tissue fibrosis, while fish receiving lycopene, citric acid, or chlorella alongside the microplastics showed substantially reduced tissue injury. The study suggests that natural antioxidant supplementation may help mitigate the harmful effects of microplastic exposure in aquaculture species.

2022 Environmental Science and Pollution Research 47 citations
Article Tier 2

Astaxanthin mitigates oxidative stress caused by microplastics at the expense of reduced skin pigmentation in discus fish

Researchers investigated how microplastics affect skin color in discus fish and whether the antioxidant astaxanthin could help. They found that microplastic exposure triggered oxidative stress that reduced skin pigmentation, and while astaxanthin supplementation improved coloring and antioxidant defenses, the pigment was diverted from skin coloration toward fighting oxidative damage. The study suggests that microplastic-induced stress forces fish to make trade-offs between maintaining body color and combating internal damage.

2023 The Science of The Total Environment 37 citations
Article Tier 2

Dietary Curcumin Promotes Gilthead Seabream Larvae Digestive Capacity and Modulates Oxidative Status

Adding curcumin to the diet of gilthead seabream larvae improved their digestive capacity and antioxidant status. The research explores natural dietary supplements for improving fish health in aquaculture, which is relevant as farmed seafood is a source of microplastic exposure for humans.

2021 Animals 19 citations
Article Tier 2

Microplastics induce toxic effects in fish: Bioaccumulation, hematological parameters and antioxidant responses

Researchers exposed juvenile fish to polyamide microplastics and found the particles accumulated primarily in the intestine, gills, and liver, causing reduced blood oxygen-carrying capacity, liver stress, and disrupted antioxidant defenses. These findings matter because fish are an important food source for humans, and microplastic accumulation in fish tissues could transfer these contaminants to people through their diet.

2025 Chemosphere 16 citations
Article Tier 2

Dietary Artemisia arborescens Supplementation Effects on Growth, Oxidative Status, and Immunity of Gilthead Seabream (Sparus aurata L.)

Researchers tested whether adding dried Artemisia arborescens plant material to fish feed could improve the health and immune response of gilthead seabream. They found that the plant supplement enhanced antioxidant capacity and boosted immune markers in the fish without negatively affecting growth. The study suggests that medicinal plant supplements in aquaculture feed could offer a sustainable alternative to antibiotics for maintaining fish health.

2024 Animals 4 citations
Article Tier 2

Micro-algal astaxanthin ameliorates polystyrene microplastics-triggered necroptosis and inflammation by mediating mitochondrial Ca2+ homeostasis in carp’s head kidney lymphocytes (Cyprinus carpio L.)

Researchers investigated whether astaxanthin, a natural pigment from microalgae, could protect carp immune cells from damage caused by polystyrene microplastics. They found that astaxanthin reduced inflammation and cell death triggered by microplastics by helping maintain calcium balance within the cells' mitochondria. The study suggests that natural antioxidant compounds may help mitigate some of the harmful immune effects of microplastic exposure in fish.

2023 Fish & Shellfish Immunology 18 citations
Article Tier 2

Effect of Scoparia dulcis Extract on Lipid Oxidation in Fish Feed, Growth Performance, and Hypoxia Tolerance in Juvenile Jian Carp (Cyprinus carpio var. Jian)

This paper is not relevant to microplastics research; it investigates the effects of Scoparia dulcis plant extracts on lipid oxidation in fish feed and growth performance in Jian carp, focusing on antioxidant and digestive outcomes.

2024 Aquaculture Nutrition 2 citations
Article Tier 2

Eco-toxicological insights: modulating bisphenol A-induced hematological changes with flaxseed diets in food fish Labeo rohita

Researchers fed flaxseed-supplemented diets to rohu fish exposed to bisphenol A to evaluate whether the dietary intervention could reduce BPA-induced hematological toxicity. Flaxseed supplementation significantly mitigated BPA-associated reductions in red blood cell count and hemoglobin, suggesting dietary omega-3 fatty acids can partially protect fish blood parameters from plastic chemical exposure.

2025 International Journal of Zoology and Applied Biosciences
Article Tier 2

L-arginine, matters for skin health of leopard coral grouper (Plectropomus leopardus)

Researchers determined that dietary L-arginine at 3.72% of dry matter optimizes growth and skin health in leopard coral grouper, enhancing pigmentation, antioxidant capacity, and immune function over an 8-week feeding trial.

2023 Research Square (Research Square)
Article Tier 2

Effect of silk fibroin microparticles on cellular immunity and liver of gilthead seabream (Sparus aurata L.) with and without experimental skin injuries

Researchers fed silk fibroin microparticles to gilthead seabream with and without experimental skin wounds, finding effects on cellular immunity and liver function, with implications for the use of microparticles in aquaculture health management.

2024 Journal of Animal Physiology and Animal Nutrition 1 citations
Article Tier 2

Dietary silymarin, Silybum marianum extract ameliorates cadmium chloride toxicity in common carp, Cyprinus carpio

Supplementing the diet of common carp with silymarin extract protected fish from cadmium chloride toxicity, with treated fish showing reduced liver damage, lower oxidative stress markers, and better growth performance compared to cadmium-exposed controls without the supplement.

2021 Annals of Animal Science 17 citations
Article Tier 2

Dietary Arthrospira platensis in Rainbow Trout (Oncorhynchus mykiss): A Means to Reduce Threats Caused by CdCl2 Exposure?

Researchers investigated whether dietary Spirulina supplementation could protect rainbow trout from cadmium chloride toxicity, evaluating growth performance, immune response, and tissue damage to assess its potential as a protective feed additive in aquaculture.

2022 Toxics 32 citations
Article Tier 2

Dietary Feeding Lycopene, Citric Acid, and Chlorella Alleviated the Neurotoxicity of Polyethylene Microplastics in African Catfish (Clarias gariepinus)

Researchers found that dietary supplementation with lycopene, citric acid, and Chlorella alleviated neurotoxic effects of polyethylene microplastics in African catfish brains, reducing oxidative damage, improving antioxidant enzyme activity, and restoring normal brain tissue histology.

2022 Frontiers in Environmental Science 31 citations
Article Tier 2

Bioremediation of hemotoxic and oxidative stress induced by polyethylene microplastic in Clarias gariepinus using lycopene, citric acid, and chlorella

Researchers found that lycopene, citric acid, and chlorella provided protective bioremediation against polyethylene microplastic toxicity in African catfish, reducing hemotoxicity, oxidative stress, and tissue accumulation of MPs in the first study of phytobioremediation against MP toxicity in fish.

2021 Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology 49 citations
Article Tier 2

Expanded utilisation of microalgae in global aquafeeds

This review explores how microalgae can be used more widely in aquaculture feeds as a sustainable replacement for fish meal and fish oil. Microalgae provide essential fatty acids, proteins, vitamins, and antioxidant pigments that support fish health and growth. While not directly about microplastics, expanding microalgae-based aquaculture feeds could reduce reliance on wild-caught fish from potentially microplastic-contaminated oceans.

2023 Reviews in Aquaculture 54 citations