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Eco-toxicological insights: modulating bisphenol A-induced hematological changes with flaxseed diets in food fish Labeo rohita

International Journal of Zoology and Applied Biosciences 2025 Score: 48 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
B. K. Anand, Vandana Garg

Summary

Researchers fed flaxseed-supplemented diets to rohu fish exposed to bisphenol A to evaluate whether the dietary intervention could reduce BPA-induced hematological toxicity. Flaxseed supplementation significantly mitigated BPA-associated reductions in red blood cell count and hemoglobin, suggesting dietary omega-3 fatty acids can partially protect fish blood parameters from plastic chemical exposure.

Body Systems

The present study was aimed to assess the effects of dietary flaxseed supplementation in mitigating the toxic impacts of Bisphenol A on the haematological parameters of food fish Labeo rohita (rohu) (Hamilton, 1822). Bisphenol A, a chemical integral to plastic manufacturing, has potential to impact humans and aquatic fauna. The experiment involves three groups: A, B, & C. The group A was served as control group, while group B was exposed to BPA dose and fed a standard diet. Group C received the same BPA dose as Group B but supplemented with a flaxseed- enriched diet. Blood samples were collected at 7th, 14th, and 21st days. Haematological parameters, including red blood cells count (RBC), haematocrit (hct) & Haemoglobin concentration (Hb), platelets count, white blood cells (WBC) count and blood indices like mean corpuscular haemoglobin (MCH) & mean corpuscular volume (MCV) were analysed. The BPA treated group shows significant (p < 0.05) changes, reduction in values of RBC, Hb, Hct, MCV and Platelets, while the value of WBC and MCH get increased. Group C shows significantly (p < 0.05) increase in Hb, RBC & platelet count, Hct percentage and in MCV value from group B. The WBC count also get increase in group C as compare to control group. The study highlights that a flaxseed diet positively impacts hematological parameters in L rohita exposed to BPA toxicity. Incorporating bioactive compounds like flaxseed into fish diets enhances their health and resilience against waterborne toxicants. Additionally, hematological parameters are identified as reliable biomarker for assessing fish health in ecotoxicological research.

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