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61,005 resultsShowing papers similar to Impact of microplastics on the intestinal microbiota: A systematic review of preclinical evidence
ClearImpact of microplastics on the human gut microbiome: a systematic review of microbial composition, diversity, and metabolic disruptions
This systematic review of 12 studies found that microplastics including polyethylene, polystyrene, and PVC induce gut dysbiosis in humans, reducing beneficial bacteria and enriching pathogens. Microplastic exposure also impairs short-chain fatty acid production and modulates immune pathways, contributing to intestinal disease, metabolic syndrome, and chronic inflammation.
Impact of microplastics on human gut microbiota: first evidences from in vitro gut models
Researchers investigated the impact of microplastics on human gut microbiota using in vitro gut models, providing early experimental evidence of how microplastic exposure may disrupt intestinal microbial communities. The study offers foundational data on microplastic-microbiome interactions that are difficult to study directly in humans.
[Effect of microand nanoplastics on the gastrointestinal mucosa and intestinal microbiome].
This review examines how micro- and nanoplastics entering through the food chain affect the gastrointestinal tract, finding evidence of disruption to gut mucosal integrity and intestinal microbiome composition, with implications for digestive health and systemic immune function.
How do microplastics affect the composition and function of gut microbiota?
Researchers reviewed how microplastics may disrupt gut microbiota composition and metabolic function, noting that while dysbiosis is a likely outcome of exposure, the full extent of these effects in humans remains poorly characterized and understudied.
Micro(nano)plastics in food system: potential health impacts on human intestinal system.
This review assessed how micro(nano)plastics in the human food system reach the intestine and accumulate in the gut, summarizing evidence that they can alter intestinal barrier function, trigger inflammation, and disrupt the gut microbiome, with implications for long-term digestive health.
How do microplastics affect the composition and function of gut microbiota?
Researchers reviewed how microplastics may disrupt gut microbiota composition and metabolic function, noting that while dysbiosis is a likely outcome of exposure, the full scope of these effects in humans remains understudied.
Toxicological Evaluation of Effects of Some Environmental Pollutants on Intestinal Microbiota: Traditional Review
This review examines how various environmental pollutants affect the gut microbiome — the community of microorganisms in the intestinal tract. Microplastics are among the pollutants discussed, and their ability to alter gut microbiota composition is increasingly recognized as a mechanism by which plastic particles may harm human and animal health.
Gut microbiome remodeling induced by microplastic exposure in humans
This review synthesizes evidence on how microplastic exposure affects the human gut microbiome, drawing on cross-sectional studies of people exposed through plastic food containers and other sources. Evidence indicates that microplastic exposure is associated with shifts in gut bacteria composition, including increases in certain bacterial groups linked to inflammation. The authors explore potential connections between microplastic-induced changes in gut bacteria and the development of various health conditions.
Immunotoxicity and intestinal effects of nano- and microplastics: a review of the literature
This review examines the evidence on how nano- and microplastics affect the immune system and intestinal health. The findings suggest that exposure to these particles can disrupt the gut microbiome and impair critical intestinal barrier functions, potentially contributing to the development of chronic inflammatory and immune conditions.
Impacts of microplastics on gut health: Current status and future directions
This systematic review found consistent evidence across mouse, fish, and earthworm models that microplastics disrupt gut microbiota composition, impair intestinal barrier integrity, and trigger gastrointestinal inflammation. The correlation between microplastic exposure and gut health deterioration was statistically significant across all animal models examined.
The microplastic-crisis: Role of bacteria in fighting microplastic-effects in the digestive system
This review examines how microplastics affect the human digestive system and explores whether certain bacteria could help counteract the damage. Microplastics disrupt the gut by altering microbial communities, interfering with digestive enzymes, and damaging the protective mucus lining. The authors highlight the potential for probiotic bacteria to bind to microplastics, reduce inflammation, and help repair the gut environment, offering a possible protective strategy against microplastic-related digestive harm.
Gut microbiota as an emerging target for the health implications of microplastics
This review examines how microplastic exposure disrupts the gut microbiome, finding evidence that microplastics damage intestinal barrier proteins, promote inflammation and oxidative stress, and may drive systemic effects including neurotoxicity and reproductive toxicity through gut-mediated pathways.
Association between microplastics exposure and gut microbiota and metabolites in older adults: A cross-sectional study
Researchers analyzed fecal samples from 45 older adults to assess the relationship between microplastic exposure and gut microbiota. They found an average of 70 microplastic particles per gram of feces, primarily PVC, butadiene rubber, and polyethylene, and observed that microplastic exposure was associated with changes in gut microbial diversity and metabolite levels. The study suggests that microplastics may influence gut health in older adults by altering bacterial community composition and metabolic pathways.
The ant that may well destroy a whole dam: a systematic review of the health implication of nanoplastics/microplastics through gut microbiota
This systematic review summarizes existing research on how nanoplastics and microplastics disrupt gut bacteria in various organisms. The findings show that plastic particle exposure consistently alters gut microbiome composition, which in turn affects the host's immune function, metabolism, and overall health. These gut bacteria changes may be a key pathway through which microplastics harm human health.
Perturbation of gut microbiota plays an important role in micro/nanoplastics-induced gut barrier dysfunction
Researchers investigated how micro- and nanoplastics disrupt gut barrier function in mice, finding that different surface chemistries caused varying levels of damage. The study suggests that these plastic particles harm the gut by altering the gut microbiome, which then leads to inflammation and weakening of the intestinal barrier that normally keeps harmful substances out of the body.
Microplastics and their interactions with microbiota
This review examines how microplastics interact with microbiota (the communities of microorganisms in the environment and in living bodies). Microplastics can carry harmful bacteria and disrupt the natural balance of microbial communities in soil, water, and the human gut. The disruption of gut microbiota by microplastics is particularly concerning because a healthy gut microbiome is essential for immune function, digestion, and overall health.
Potential effects of MPs and their co-pollutants on human intestinal tract
This review examines how microplastics and their co-pollutants enter and damage the human intestinal tract, summarizing evidence for microplastic-induced gut barrier disruption, microbiota alteration, and systemic translocation to other organs.
Micro- and nano-plastics, intestinal inflammation, and inflammatory bowel disease: A review of the literature
This review summarizes the growing evidence linking micro- and nanoplastic exposure to intestinal inflammation and inflammatory bowel disease (IBD). Studies show these tiny plastic particles can trigger immune responses in the gut, alter the gut microbiome, and worsen intestinal inflammation, though more research using standardized methods is needed to confirm these effects in humans.
Micro(nano)plastics and Their Potential Impact on Human Gut Health: A Narrative Review
This review summarizes research on how micro- and nanoplastics affect the gut, finding that they can damage the intestinal lining, trigger immune responses, and disrupt the balance of beneficial gut bacteria in both cell studies and animal models. Since humans are primarily exposed to microplastics through food and food packaging, understanding these gut effects is essential for assessing the true health risks of plastic pollution.
Microbial risks associated with microplastics in the food chain and possible control measures (literature review). Part 1. Dietary intake and influence on the gut microbiota
This review summarizes evidence that microplastics commonly found in food and drinking water can disrupt the human gut microbiome when ingested. Studies show that microplastics alter the composition and function of intestinal bacteria, potentially affecting digestion, immunity, and overall health. Since a healthy gut microbiome is essential for human wellbeing, this pathway of harm deserves attention alongside other known risks of microplastic exposure.
Microplastics and the gut microbiome: Emerging health concerns and strategies
This review covers how microplastic ingestion affects the gut microbiome, describing mechanisms by which microplastics cause intestinal disorders, disrupt endocrine function, and promote pathogenic bacterial growth, while also noting inhalation and dermal absorption as secondary exposure routes.
Effects induced by polyethylene microplastics oral exposure on colon mucin release, inflammation, gut microflora composition and metabolism in mice
Researchers fed mice polyethylene microplastics for 30 days and found that even low doses reduced protective mucus in the colon, altered inflammation markers, and shifted the composition of gut bacteria. The microplastics increased the ratio of Bacteroides to Firmicutes bacteria and affected metabolic pathways in the gut microbiome. The study suggests that oral microplastic exposure may disrupt intestinal health by modifying the gut microbial community and its metabolism.
Polyethylene microplastics affect the distribution of gut microbiota and inflammation development in mice
Researchers fed mice different concentrations of polyethylene microplastics for five weeks and found significant changes in gut bacteria composition and signs of intestinal inflammation. Higher doses increased bacterial diversity and altered the balance of specific bacterial species, while triggering immune responses and inflammation in the colon and duodenum. The study provides evidence that microplastic ingestion can disrupt the gut microbiome and promote intestinal inflammation in mammals.
Quantitative evaluation of microplastic interference with gut microbiota: Identifying sensitive indicators and key factors
This meta-analysis combined with machine learning found that the Firmicutes-to-Bacteroidetes ratio is the most sensitive biomarker of microplastic-induced gut microbiome disruption, with exposure concentration, particle size, and duration as the key drivers. The resulting predictive model (R=0.91) offers a quantitative tool for assessing gastrointestinal harm from microplastic exposure.