We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
How do microplastics affect the composition and function of gut microbiota?
Summary
Researchers reviewed how microplastics may disrupt gut microbiota composition and metabolic function, noting that while dysbiosis is a likely outcome of exposure, the full scope of these effects in humans remains understudied.
Microplastics may disrupt the gut microbiota, leading to dysbiosis and altered metabolic functions, although the full extent in humans remains under-researched.
Sign in to start a discussion.
More Papers Like This
How do microplastics affect the composition and function of gut microbiota?
Researchers reviewed how microplastics may disrupt gut microbiota composition and metabolic function, noting that while dysbiosis is a likely outcome of exposure, the full extent of these effects in humans remains poorly characterized and understudied.
Microplastics and their interactions with microbiota
This review examines how microplastics interact with microbiota (the communities of microorganisms in the environment and in living bodies). Microplastics can carry harmful bacteria and disrupt the natural balance of microbial communities in soil, water, and the human gut. The disruption of gut microbiota by microplastics is particularly concerning because a healthy gut microbiome is essential for immune function, digestion, and overall health.
Gut microbiota, a key to understanding the knowledge gaps on micro-nanoplastics-related biological effects and biodegradation
This review explores how micro- and nanoplastics affect the community of microorganisms living in the gut, and how those same gut microbes might be able to break down plastic particles. Swallowed microplastics can disrupt the balance of gut bacteria, potentially leading to various diseases. On the other hand, some gut bacteria can actually degrade plastics into smaller, less harmful molecules, opening a possible avenue for biological cleanup.
Impact of microplastics on the human gut microbiome: a systematic review of microbial composition, diversity, and metabolic disruptions
This systematic review of 12 studies found that microplastics including polyethylene, polystyrene, and PVC induce gut dysbiosis in humans, reducing beneficial bacteria and enriching pathogens. Microplastic exposure also impairs short-chain fatty acid production and modulates immune pathways, contributing to intestinal disease, metabolic syndrome, and chronic inflammation.
Impact of microplastics on the intestinal microbiota: A systematic review of preclinical evidence
Across 28 preclinical studies, microplastics triggered intestinal dysbiosis characterized by increased Firmicutes and Proteobacteria and decreased Bacteroidetes, while increasing gut permeability and elevating pro-inflammatory cytokines including IL-1β, TNF-α, and IL-6.