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20 resultsShowing papers similar to Reduction in Toxicity of Polystyrene Nanoplastics Combined with Phenanthrene through Binding of Jellyfish Mucin with Nanoplastics
ClearToxicity of nanoplastics for zebrafish embryos, what we know and where to go next
This review integrates findings from studies on how polystyrene nanoplastics affect zebrafish embryo development, a widely used model for understanding toxicity. Researchers found that the functional coating on nanoplastic surfaces had a greater influence on toxic effects than particle size or concentration alone. The study highlights that surface chemistry is a critical and often overlooked factor in nanoplastic toxicity, and calls for more standardized study designs to improve comparability across research.
Screening of the Toxicity of Polystyrene Nano- and Microplastics Alone and in Combination with Benzo(a)pyrene in Brine Shrimp Larvae and Zebrafish Embryos
Researchers found that polystyrene nano- and microplastics alone showed minimal acute toxicity to brine shrimp and zebrafish embryos, but when combined with benzo(a)pyrene, the plastics altered the pollutant's bioavailability and toxic effects.
Molecular effects of polystyrene nanoplastics toxicity in zebrafish embryos (Danio rerio)
Researchers exposed zebrafish embryos to polystyrene nanoplastics at various concentrations and measured gene expression changes related to stress, inflammation, and DNA repair. They found dose-dependent activation of oxidative stress and apoptotic pathways at the highest concentration, along with inhibition of the neurotransmitter-related gene acetylcholinesterase and DNA repair genes. The study suggests that nanoplastic exposure at the molecular level may compromise cellular defense mechanisms and neurological function in developing fish.
Mechanisms of parental co-exposure to polystyrene nanoplastics and microcystin-LR aggravated hatching inhibition of zebrafish offspring
Zebrafish parents co-exposed to microcystin-LR and polystyrene nanoplastics produced offspring with greater MCLR accumulation and more severe hatching inhibition than MCLR alone, with nanoplastics acting as a carrier that enhanced toxin transfer to embryos.
Low level of polystyrene microplastics decreases early developmental toxicity of phenanthrene on marine medaka (Oryzias melastigma)
Researchers exposed marine medaka fish eggs to low levels of polystyrene microplastics combined with the pollutant phenanthrene. Surprisingly, they found that a very low concentration of microplastics actually reduced the developmental toxicity of phenanthrene, improving hatch rates and decreasing malformations. The study suggests this protective effect occurs because the microplastics reduce the bioavailability of the chemical pollutant, challenging the assumption that microplastics always worsen the toxicity of co-occurring contaminants.
Toxicological impacts of nanopolystyrene on zebrafish oocyte with insight into the mechanism of action: An expression-based analysis
Researchers investigated the mechanism by which nanopolystyrene causes toxicity in zebrafish oocytes, finding it triggers oxidative stress, immune disruption, and mitochondrial dysfunction through changes in key gene expression pathways.
Polystyrene nanoplastics mediated the toxicity of silver nanoparticles in zebrafish embryos
Researchers studied how polystyrene nanoplastics interact with silver nanoparticles and affect zebrafish embryo development. They found that nanoplastics can act as carriers for silver nanoparticles in water, and the combination altered patterns of oxidative stress, immune response, and metabolic function compared to either pollutant alone. The study highlights how nanoplastics may change the way other environmental contaminants affect aquatic organisms.
Complex combined effects of polystyrene nanoplastics and phenanthrene in aquatic models
Researchers investigated the combined toxicity of polystyrene nanoplastics and the pollutant phenanthrene in fish cells and zebrafish larvae. They found that the interaction between nanoplastics and phenanthrene was complex and tissue-dependent, with nanoplastics increasing phenanthrene uptake in some cell types while decreasing it in others. Interestingly, zebrafish larvae experienced lower overall toxicity during co-exposure compared to single-pollutant exposure, suggesting the interaction dynamics are more nuanced than previously assumed.
The role of nanoplastics on the toxicity of the herbicide phenmedipham, using Danio rerio embryos as model organisms
Researchers found that polystyrene nanoplastics altered the toxicity of the herbicide phenmedipham to zebrafish embryos, with combined exposure producing different developmental effects than either contaminant alone, suggesting nanoplastics can modify pesticide bioavailability.
Uptake Routes and Biodistribution of Polystyrene Nanoplastics on Zebrafish Larvae and Toxic Effects on Development
Researchers exposed zebrafish embryos and larvae to amino-modified polystyrene nanoplastics to study uptake routes and biodistribution. The study found that nanoplastics accumulated in target organs and caused toxic developmental effects, providing evidence that these tiny plastic fragments can penetrate biological barriers and interfere with normal development in aquatic organisms.
Polystyrene Nanoplastic Exposure Induces Developmental Toxicity by Activating the Oxidative Stress Response and Base Excision Repair Pathway in Zebrafish (Danio rerio)
Researchers exposed zebrafish embryos to polystyrene nanoplastics at various concentrations and found significant developmental abnormalities including reduced hatching rates and increased malformations. The nanoplastics activated oxidative stress responses and DNA repair pathways, indicating cellular damage during critical early development stages. The study provides mechanistic evidence for how nanoplastic exposure can disrupt normal embryonic development in aquatic organisms.
Bioaccumulation of polystyrene nanoplastics and their effect on the toxicity of Au ions in zebrafish embryos
Researchers studied the bioaccumulation of polystyrene nanoplastics in zebrafish embryos and their interaction with gold ions. They found that smaller nanoplastics readily penetrated the embryo's protective membrane and accumulated in lipid-rich regions, particularly the yolk. While nanoplastics alone caused only marginal toxic effects, their presence synergistically amplified the toxicity of gold ions through increased oxidative stress and inflammatory responses, suggesting that nanoplastics may worsen the harmful effects of co-occurring environmental contaminants.
Developmental toxicity of functionalized polystyrene microplastics and their inhibitory effects on fin regeneration in zebrafish
Researchers exposed zebrafish to polystyrene microplastics with different surface modifications and found that all types caused developmental toxicity, including increased mortality, reduced body length, and impaired swimming ability. The amino-modified particles were generally the most harmful, also inhibiting fin regeneration after injury. The study suggests that surface chemistry plays a critical role in determining how microplastics interact with biological systems.
Bisphenol A decreases the developmental toxicity and histopathological alterations caused by polystyrene nanoplastics in developing marine medaka Oryzias melastigma
Researchers found that bisphenol A unexpectedly decreased the developmental toxicity and histopathological damage caused by polystyrene nanoplastics in marine medaka embryos, suggesting complex antagonistic interactions between co-existing pollutants at environmentally relevant concentrations.
Polystyrene Nanoplastic Exposure Adversely Affects Survivability of Zebrafish Larvae
Researchers found that polystyrene nanoplastic exposure significantly reduces survival rates of zebrafish larvae in a dose-dependent manner, documenting behavioral abnormalities and developmental defects that highlight the toxicity of nanoscale plastic particles to early vertebrate life.
The presence of polystyrene nanoplastics enhances the MCLR uptake in zebrafish leading to the exacerbation of oxidative liver damage
Researchers found that polystyrene nanoplastics enhanced the uptake of the toxin microcystin-LR in zebrafish liver over three months of co-exposure, exacerbating oxidative damage and cellular swelling compared to microcystin exposure alone.
Effects of polystyrene nanoplastic size on zebrafish embryo development
Researchers exposed zebrafish embryos to polystyrene nanoplastics of four sizes and found only the smallest (30 nm) caused mortality and altered oxidative stress and apoptosis gene expression, while larger particles (100–450 nm) were ingested and accumulated in the digestive system without causing developmental malformations.
Polystyrene nanoplastics alter the cytotoxicity of human pharmaceuticals on marine fish cell lines
Researchers exposed marine fish cell lines to polystyrene nanoplastics and found that while the nanoplastics alone were not directly toxic, they significantly altered the cytotoxicity of human pharmaceuticals, with one cell line proving more sensitive than the other, underscoring how nanoplastics can change the hazard profile of co-occurring chemical pollutants.
Polystyrene microplastics alleviate the developmental toxicity of silver nanoparticles in embryo-larval zebrafish (Danio rerio) at the transcriptomic level
In a surprising finding, researchers discovered that when zebrafish embryos were exposed to both silver nanoparticles and polystyrene microplastics together, the microplastics actually reduced the toxic effects of the silver nanoparticles. The study suggests that microplastics may interact with other pollutants in complex ways, sometimes lessening rather than amplifying their harmful impacts on developing organisms.
Intrinsic interaction inferred oxidative stress and apoptosis by Biosurfactant-microplastic hybrid reduces coordinated in vivo biotoxicity in zebrafish (Danio rerio)
Researchers developed a biosurfactant-microplastic hybrid and tested whether coating microplastics with biosurfactant could reduce their toxicity in zebrafish. They found that the biosurfactant coating reduced oxidative stress and cell death caused by the microplastics, lowering their overall biological harm. The study suggests that biosurfactants could potentially serve as a mitigation strategy for reducing microplastic toxicity in aquatic environments.