Papers

61,005 results
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Article Tier 2

Transcriptomic, histological and biochemical analyses of Macrobrachium nipponense response to acute heat stress

This study examined how acute heat stress affects the physiology of the oriental river prawn, finding significant changes in gene expression and biochemistry that provide insight into how this commercially important species responds to warming water temperatures.

2022 Research Square (Research Square) 4 citations
Article Tier 2

Metabonomic Analysis of Macrobrachium rosenbergii with Iron Prawn Syndrome (IPS)

Researchers performed metabonomic and RNA-seq analyses of freshwater prawns (Macrobrachium rosenbergii) affected by Iron Prawn Syndrome, identifying hundreds of differentially expressed proteins and key metabolic pathway disruptions that shed light on the molecular basis of this disease.

2023 Fishes 1 citations
Article Tier 2

Two genes related to apoptosis in the hepatopancreas of juvenile prawn, Macrobrachium nipponense: Molecular characterization and transcriptional response to nanoplastic exposure

Researchers identified and characterized two apoptosis-related genes in juvenile prawns exposed to polystyrene nanoplastics, finding that nanoplastic exposure induced significant apoptotic responses in hepatopancreas tissue in a concentration-dependent manner.

2023 The Science of The Total Environment 11 citations
Article Tier 2

Transcriptome Analysis of Gills Provides Insights Into Translation Changes Under Hypoxic Stress and Reoxygenation in Golden Pompano, Trachinotus ovatus (Linnaeus 1758)

This transcriptome study found that oxygen deprivation suppresses immune genes in the gills of golden pompano fish, potentially explaining why fish are more susceptible to infections under low-oxygen aquaculture conditions. The molecular findings support improved oxygen management practices in fish farming to protect both animal welfare and food quality.

2021 Frontiers in Marine Science 21 citations
Article Tier 2

Noncoding Variation and Transcriptional Plasticity Promote Thermal Adaptation in Oysters by Altering Energy Metabolism

Comparative genomic and transcriptomic analysis of two closely related oyster species from warm and cold environments found that noncoding sequence divergence and adaptive transcriptional plasticity underpin thermal adaptation, with warm-adapted oysters showing higher plasticity in energy metabolism genes that up-regulate ATP production and lipid catabolism in response to heat.

2021 Molecular Biology and Evolution 68 citations
Article Tier 2

Two genes related to reproductive development in the juvenile prawn, Macrobrachium nipponense: Molecular characterization and transcriptional response to nanoplastic exposure

Nanoplastic exposure altered the expression of two genes involved in reproductive development in juvenile freshwater prawns (Macrobrachium nipponense), suggesting that nanoplastics may disrupt reproductive pathways in crustaceans at low concentrations.

2021 Chemosphere 17 citations
Article Tier 2

Molecular Characterization of Anion Exchanger 2 in Litopenaeus vannamei and Its Role in Nitrite Stress

Scientists cloned and characterized the AE2 gene in Pacific white shrimp (Litopenaeus vannamei), finding it plays a key role in regulating intracellular pH; silencing AE2 via RNA interference significantly increased shrimp mortality and tissue damage under nitrite stress.

2025 International Journal of Molecular Sciences
Article Tier 2

Change in energy-consuming strategy, nucleolar metabolism and physical defense in Macrobrachium rosenbergii after acute and chronic polystyrene nanoparticles exposure

Researchers examined how polystyrene nanoplastic exposure affects freshwater prawns over both short-term and long-term periods, finding significant changes in gene expression related to energy metabolism and physical defense. The study revealed that nanoplastic exposure disrupted nucleolar metabolism and triggered shifts in energy-consuming strategies, suggesting these particles pose a meaningful threat to aquatic crustaceans.

2023 Aquatic Toxicology 12 citations
Article Tier 2

Effects of salinity acclimation on histological characteristics and miRNA expression profiles of scales in juvenile rainbow trout (Oncorhynchus mykiss)

Researchers investigated how rainbow trout adapt their scales at the molecular level when moved from freshwater to saltwater, identifying specific small RNA molecules (microRNAs) that regulate bone metabolism during the transition. This foundational biology work helps explain how fish adapt to changing environments, relevant to aquaculture and to understanding how fish physiology responds to environmental stressors like microplastic exposure.

2022 BMC Genomics 19 citations
Article Tier 2

Effects of nanoplastic on cell apoptosis and ion regulation in the gills of Macrobrachium nipponense

Researchers exposed juvenile oriental river shrimp to varying concentrations of nanoplastics and examined effects on gill cell viability and ion regulation. They found that higher nanoplastic concentrations increased cell death rates, decreased ion content, reduced ATPase enzyme activity, and disrupted ion transport gene expression in gill tissues. The study suggests that nanoplastic pollution can impair critical ion regulation functions in freshwater crustaceans, with implications for aquaculture.

2022 Environmental Pollution 51 citations
Article Tier 2

Transcriptome analysis provides insights into copper toxicology in piebald naked carp (Gymnocypris eckloni)

Researchers exposed piebald naked carp to copper — a common water pollutant — and found it significantly disrupted gene activity in the gills and liver, particularly genes involved in building proteins, suggesting that fish respond to metal-induced stress by broadly slowing down protein production as a protective mechanism.

2021 BMC Genomics 16 citations
Article Tier 2

Acute and chronic effects of polystyrene microplastics on brine shrimp: First evidence highlighting the molecular mechanism through transcriptome analysis

Researchers investigated both acute and chronic toxicity of polystyrene microplastics on brine shrimp, using transcriptome analysis to uncover molecular mechanisms. While acute exposure did not significantly affect survival, chronic exposure led to concentration-dependent bioaccumulation and increased reactive oxygen species generation, with gene expression analysis revealing disrupted metabolic and stress response pathways.

2020 Journal of Hazardous Materials 176 citations
Article Tier 2

[Physiological and Ecological Response Characteristics and Transcriptomic Change Characteristics of Rice (Oryza sativa)Under Different Microplastic Stresses].

Researchers used transcriptomic analysis to characterize physiological and ecological response characteristics of an aquatic organism exposed to microplastic stress, identifying gene expression changes in pathways related to immune function, oxidative stress, and energy metabolism.

2025 PubMed
Article Tier 2

Acclimatory gene expression of primed clams enhances robustness to elevated pCO2

Pacific geoduck clams pre-exposed to elevated CO2 showed acclimatory gene expression changes that improved their growth and antioxidant responses when later exposed to moderate ocean acidification conditions. The results suggest epigenetic-like transcriptional priming may help shellfish populations cope with progressive ocean acidification.

2022 Molecular Ecology 17 citations
Article Tier 2

De novo assembly of the Carcinus maenas transcriptome and characterization of innate immune system pathways

Researchers assembled a comprehensive genetic transcript library (transcriptome) for the European shore crab (Carcinus maenas), a widely studied species, and identified key genes and pathways involved in its immune system. This genetic resource will help scientists study how crabs respond to environmental stressors, including microplastic exposure.

2015 BMC Genomics 57 citations
Article Tier 2

Rapid epigenetic response to salinity stress in an invasive mussel, Mytilus galloprovincialis

Researchers exposed the invasive mussel Mytilus galloprovincialis to rapid salinity decreases and tracked DNA methylation changes over 24 hours, finding that epigenetic modifications continued to evolve throughout the stress period, indicating dynamic regulatory responses to acute environmental change.

2025 TURKISH JOURNAL OF ZOOLOGY
Review Tier 2

The Next Generation Is Here: A Review of Transcriptomic Approaches in Marine Ecology

This review assessed transcriptomic approaches in marine ecology, highlighting how next-generation sequencing technologies are enabling researchers to address ecological questions including organism responses to environmental stressors at the molecular level.

2022 Frontiers in Marine Science 26 citations
Article Tier 2

Hypoxia in the Blue Mussel Mytilus chilensis Induces Transcriptome Shift Associated with Endoplasmic Reticulum Stress, Metabolism, and Immune Response.

Scientists used gene expression analysis to study how low-oxygen conditions affect the blue mussel Mytilus chilensis at the molecular level. Researchers found that hypoxia triggered stress responses in the mussels' gills, digestive glands, and muscles, including cellular stress pathways, metabolic shifts, and immune changes. The study highlights how climate-driven oxygen depletion in coastal waters can stress economically important shellfish species.

2024 Preprints.org 5 citations
Article Tier 2

Transcriptome Analysis Revealed the Early Heat Stress Response in the Brain of Chinese Tongue Sole (Cynoglossus semilaevis)

Researchers used transcriptome analysis to study how the brains of Chinese tongue sole fish respond to short-term heat stress. They identified distinct gene expression patterns in male and female fish, with key pathways related to cortisol production, immune signaling, and stress-response genes like heat shock proteins. The study provides new insights into the sex-specific brain mechanisms fish use to cope with temperature changes.

2023 Animals 12 citations
Article Tier 2

Ion transport and metabolic regulation induced by nanoplastic toxicity in gill of Litopenaeus vannamei using proteomics

Researchers used proteomics to study how nanoplastics affect the gills of Pacific white shrimp, a widely farmed seafood species. They found that high concentrations of nanoplastics damaged gill tissue, disrupted ion balance, triggered oxidative stress, and altered energy metabolism. The study reveals the molecular mechanisms through which nanoplastic pollution may threaten the health of commercially important aquaculture species.

2025 Environmental Science Nano 2 citations
Article Tier 2

Role of Mn-LIPA in Sex Hormone Regulation and Gonadal Development in the Oriental River Prawn, Macrobrachium nipponense

Researchers cloned and characterized the lysosomal acid lipase gene Mn-LIPA from the oriental river prawn Macrobrachium nipponense and examined its role in sex hormone regulation and gonadal development. The study found that Mn-LIPA expression patterns correlate with reproductive maturation and sex-specific hormone profiles in this commercially farmed freshwater shrimp.

2024 International Journal of Molecular Sciences 7 citations
Article Tier 2

Transcriptomic analysis following polystyrene nanoplastic stress in the Pacific white shrimp, Litopenaeus vannamei

Researchers used transcriptomic analysis to study how polystyrene nanoplastics affect gene expression in Pacific white shrimp. They found that nanoplastic exposure activated lysosome pathways and disrupted genes involved in immune response, protein processing, and metabolism. The study provides molecular-level evidence that nanoplastics can interfere with multiple biological systems in commercially important shrimp species.

2023 Fish & Shellfish Immunology 15 citations
Article Tier 2

Transcriptional response in the whiteleg shrimp (Penaeus vannamei) to short-term microplastic exposure

Researchers exposed whiteleg shrimp (Penaeus vannamei) to microplastics for 96 hours and used transcriptomics to profile gene expression changes, finding significant upregulation of stress response, immune, and detoxification pathways, indicating that even short-term microplastic exposure triggers a broad molecular stress response.

2021 Aquaculture Reports 26 citations
Article Tier 2

Copper-Induced Ionoregulatory Disturbance, Histopathology, and Transcriptome Responses in Freshwater Mussel (Anodonta woodiana) Gills

Researchers investigated copper toxicity in the freshwater mussel Anodonta woodiana, finding that sublethal exposure caused ionoregulatory disturbance, gill histopathology, and significant transcriptomic changes related to stress response and immune function.

2023 Fishes 10 citations