Papers

20 results
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Article Tier 2

Effect of chlorpyrifos on freshwater microbial community and metabolic capacity of zebrafish

Researchers exposed zebrafish and their surrounding water to chlorpyrifos, a widely used pesticide, and found it disrupted the diversity of aquatic microbes, increased dangerous antibiotic-resistant bacteria, and altered the gut metabolism of fish — raising concerns about the ecological and food-safety risks of pesticide runoff into waterways.

2023 Ecotoxicology and Environmental Safety 15 citations
Article Tier 2

Polystyrene microplastics induce gut microbiome and metabolome changes in Javanese medaka fish (Oryzias javanicus Bleeker, 1854)

Researchers found that polystyrene microplastic exposure altered gut microbiome composition and metabolic profiles in Javanese medaka fish, with effects on amino acid and lipid metabolism pathways suggesting microplastics can disrupt gut health in aquatic organisms.

2022 Toxicology Reports 33 citations
Article Tier 2

Metagenomic analysis explores the interaction of aged microplastics and roxithromycin on gut microbiota and antibiotic resistance genes of Carassius auratus

Researchers examined how aged polystyrene microplastics interact with the antibiotic roxithromycin in the gut of goldfish using metagenomic analysis. They found that aging enhanced the microplastics' ability to carry and release the antibiotic, leading to greater intestinal inflammation and disruption of gut microbial communities. The combined exposure also selectively enriched antibiotic resistance genes, suggesting that aged microplastics may amplify the ecological risks of antibiotic pollution.

2021 Journal of Hazardous Materials 93 citations
Article Tier 2

Legacy metal contamination is reflected in the fish gut microbiome in an urbanised estuary

Researchers found that legacy metal contamination in a heavily urbanized estuary in Australia is altering the gut microbiome of local fish, with metal-exposed fish harboring more potentially harmful and inflammation-linked bacteria. This shows that gut microbiome changes in fish can serve as a sensitive biological indicator of environmental pollution, even when the contamination occurred decades ago.

2022 Environmental Pollution 24 citations
Article Tier 2

Plastics in our water: Fish microbiomes at risk?

This review examined how microplastics and leached plasticizers affect the gut microbiomes of freshwater and marine fish, summarizing evidence for dysbiosis and reduced microbial diversity and discussing potential consequences for fish immunity, metabolism, and environmental fitness.

2021 Comparative Biochemistry and Physiology Part D Genomics and Proteomics 25 citations
Article Tier 2

Within-species variation in the gut microbiome of medaka ( Oryzias latipes ) is driven by the interaction of light intensity and genetic background

This study found that gut microbiome composition in medaka fish is shaped by the interaction between genetic background and light intensity, with fishing-like selective pressure reducing bacterial richness under low-light conditions, though this did not affect growth rates.

2023
Article Tier 2

Persistent Dysbiosis, Parasite Rise and Growth Impairment in Aquacultured European Seabass after Oxytetracycline Treatment

Researchers tracked gut microbiota changes in European seabass after oxytetracycline antibiotic treatment in an aquaculture setting and observed persistent dysbiosis and increased parasite levels. The study found that surviving fish displayed measurable growth impairment linked to disrupted gut microbial communities, highlighting unintended consequences of antibiotic use in fish farming.

2023 Microorganisms 8 citations
Article Tier 2

Incomplete recovery of gut microbiota in marine medaka (Oryzias melastigma) during the depuration phase, after exposure to sulfamethazine/nanoplastics

Researchers found that gut microbiota in marine medaka did not fully recover after 21 days of depuration following exposure to sulfamethazine and polystyrene nanoplastics, indicating that antibiotic and nanoplastic co-exposure can cause lasting disruption to fish gut microbial communities.

2023 The Science of The Total Environment 10 citations
Article Tier 2

Gut microbiota related response of Oryzias melastigma to combined exposure of polystyrene microplastics and tetracycline

Researchers exposed estuarine fish to polystyrene microplastics and the antibiotic tetracycline, both alone and in combination, for four weeks. The combined exposure caused more severe disruption to gut bacteria and liver tissue than either pollutant alone, with microplastics appearing to worsen the effects of tetracycline. The study suggests that the co-occurrence of microplastics and antibiotics in coastal waters may pose greater ecological risks than either contaminant by itself.

2023 The Science of The Total Environment 18 citations
Article Tier 2

Effects of Long-Term Triclosan Exposure on Microbiota in Zebrafish

Long-term exposure to triclosan at environmentally relevant concentrations significantly altered gut microbiota composition in zebrafish, reducing microbial diversity and shifting community structure in ways that could affect host immune function and metabolism.

2021 Frontiers in Microbiology 10 citations
Article Tier 2

Subchronic toxicity of dietary sulfamethazine and nanoplastics in marine medaka (Oryzias melastigma): Insights from the gut microbiota and intestinal oxidative status

Researchers found that dietary co-exposure to the antibiotic sulfamethazine and polystyrene nanoplastics in marine medaka caused significant disruption of gut microbiota composition and increased intestinal oxidative stress, with combined effects exceeding individual exposures.

2021 Ecotoxicology and Environmental Safety 48 citations
Article Tier 2

Establishment of the Bacterial Microbiota in a Lab-Reared Model Teleost Fish, the Medaka Oryzias latipes

Researchers established a detailed characterization of the bacterial microbiota in lab-reared medaka (Oryzias latipes) across life stages from larvae to adults, addressing a significant knowledge gap in this important aquatic ecotoxicology model organism.

2022 Microorganisms 14 citations
Article Tier 2

Deciphering the gut microbiome of grass carp through multi-omics approach

This multi-omics study profiled the gut microbiome, transcriptome, and metabolome of grass carp to identify microbial species and metabolic pathways that support host metabolism and immunity, providing a foundation for developing microbiome-targeted feed additives as antibiotic alternatives in aquaculture.

2023 3 citations
Article Tier 2

Network analysis reveals significant joint effects of microplastics and tetracycline on the gut than the gill microbiome of marine medaka

Researchers used network analysis to study the joint effects of polystyrene microplastics and the antibiotic tetracycline on the gut and gill microbiomes of marine medaka fish over 30 days. The study found that combined exposure had more profound effects on the gut than the gill microbiome, reducing the complexity and stability of gut microbial networks.

2022 Journal of Hazardous Materials 58 citations
Article Tier 2

Chronic Exposure of Adult Zebrafish to Polyethylene and Polyester-based Microplastics: Metabolomic and Gut Microbiome Alterations Reflecting Dysbiosis and Resilience

Researchers exposed adult zebrafish to polyethylene and polyester microplastics at environmentally relevant concentrations and found significant disruptions to metabolic pathways and gut microbiome composition. Polyethylene primarily affected cell membrane compounds and inflammation-related metabolites, while polyester altered lipid metabolism and gut bacterial interactions. The study reveals that chronic microplastic exposure can cause subtle but meaningful shifts in fish metabolism and gut health, even at low concentrations.

2024 Journal of Hazardous Materials 9 citations
Article Tier 2

Modern research on the study of the intestinal microbiome in fish (review)

This review examines recent research on the intestinal microbiome of fish, synthesizing findings on microbiome composition across more than 100 teleost species and exploring the microbiome as a potential biomarker for fish health and aquaculture optimization.

2023 Animal Husbandry and Fodder Production 4 citations
Article Tier 2

Pathophysiological impact of chronic exposure of ciprofloxacin antibiotic residue above the MRL level in mice

Researchers chronically exposed organisms to ciprofloxacin antibiotic residues at environmentally relevant concentrations, measuring physiological and pathological responses. Ciprofloxacin exposure caused oxidative stress, tissue damage, and dysregulation of immune markers, suggesting that sub-therapeutic antibiotic concentrations common in polluted water pose meaningful health risks to aquatic organisms.

2024
Article Tier 2

Effects of environmental factors on host-microbiota interactions in the guts of aquatic organisms: A review

This review synthesizes how environmental stressors — including microplastics, heavy metals, photoperiod, and aquaculture feed additives — alter gut microbiota in fish and aquatic invertebrates, identifying common patterns of microbial disruption and compromised gut barrier integrity.

2025 Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology 2 citations
Article Tier 2

A fishy gut feeling – current knowledge on gut microbiota in teleosts

This review summarizes what scientists know about the community of bacteria living in fish guts and how diet, environmental conditions, and pollutants shape that community. Microplastics and other pollutants can disrupt the gut microbiome in fish, harming their immune function and overall health. Since fish are a major food source for humans, understanding these effects matters for food safety.

2025 Frontiers in Marine Science 14 citations
Article Tier 2

Gut microbiota of aquatic organisms: A key endpoint for ecotoxicological studies

This review examines how environmental contaminants including microplastics, pesticides, heavy metals, and pharmaceuticals affect the gut microbiota of aquatic organisms. Researchers highlight that changes in gut bacterial communities can serve as sensitive indicators of pollution exposure and may have downstream effects on host fitness. The study calls for improved methodologies to better link contaminant-induced shifts in gut microbiota to measurable health outcomes in aquatic species.

2019 Environmental Pollution 261 citations