Papers

20 results
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Article Tier 2

Transcriptome Analysis of Gills Provides Insights Into Translation Changes Under Hypoxic Stress and Reoxygenation in Golden Pompano, Trachinotus ovatus (Linnaeus 1758)

This transcriptome study found that oxygen deprivation suppresses immune genes in the gills of golden pompano fish, potentially explaining why fish are more susceptible to infections under low-oxygen aquaculture conditions. The molecular findings support improved oxygen management practices in fish farming to protect both animal welfare and food quality.

2021 Frontiers in Marine Science 21 citations
Article Tier 2

Transcriptome Analysis Revealed the Early Heat Stress Response in the Brain of Chinese Tongue Sole (Cynoglossus semilaevis)

Researchers used transcriptome analysis to study how the brains of Chinese tongue sole fish respond to short-term heat stress. They identified distinct gene expression patterns in male and female fish, with key pathways related to cortisol production, immune signaling, and stress-response genes like heat shock proteins. The study provides new insights into the sex-specific brain mechanisms fish use to cope with temperature changes.

2023 Animals 12 citations
Article Tier 2

Transcriptome analysis provides insights into copper toxicology in piebald naked carp (Gymnocypris eckloni)

Researchers exposed piebald naked carp to copper — a common water pollutant — and found it significantly disrupted gene activity in the gills and liver, particularly genes involved in building proteins, suggesting that fish respond to metal-induced stress by broadly slowing down protein production as a protective mechanism.

2021 BMC Genomics 16 citations
Article Tier 2

Transcriptome alterations in zebrafish gill after exposure to different sizes of microplastics

Researchers found that microplastic exposure in zebrafish gills caused size-dependent transcriptomic changes, with smaller particles triggering more differentially expressed genes related to immune response, oxidative stress, and apoptosis pathways compared to larger particles.

2022 Journal of Environmental Science and Health Part A 36 citations
Article Tier 2

Transcriptomic, histological and biochemical analyses of Macrobrachium nipponense response to acute heat stress

This study examined how acute heat stress affects the physiology of the oriental river prawn, finding significant changes in gene expression and biochemistry that provide insight into how this commercially important species responds to warming water temperatures.

2022 Research Square (Research Square) 4 citations
Article Tier 2

The effects of exposure to microplastics on grass carp (Ctenopharyngodon idella) at the physiological, biochemical, and transcriptomic levels

Researchers exposed grass carp to microplastics at two concentrations for 21 days and observed liver damage, inhibited growth, and increased oxidative stress. Transcriptome analysis revealed over 1,500 differentially expressed genes related to immune response, metabolism, and cellular stress pathways. The study suggests that microplastic exposure can trigger broad physiological and molecular disruptions in freshwater fish.

2021 Chemosphere 54 citations
Article Tier 2

Effects of different temperatures on Leiocassis longirostris gill structure and intestinal microbial composition

Researchers exposed a freshwater catfish species to cold (4°C), normal (26°C), and hot (32°C) water temperatures and found that both extremes damaged gill tissue and disrupted the balance of gut bacteria, with cold stress causing a larger shift toward opportunistic pathogens. The findings reveal how temperature stress compromises fish immune health, relevant as climate change increases the frequency of extreme weather events.

2024 Scientific Reports 19 citations
Article Tier 2

Transcriptome Analysis to Study the Molecular Response in the Gill and Hepatopancreas Tissues of Macrobrachium nipponense to Salinity Acclimation

Researchers used Illumina RNA sequencing to perform transcriptome analyses of gill and hepatopancreas tissues from the freshwater prawn Macrobrachium nipponense exposed to three salinity levels. They identified differentially expressed genes related to ion transport, oxidative phosphorylation, and glycometabolism, and confirmed carbonic anhydrase as a key regulator of osmotic adaptation through in situ hybridization.

2022 Frontiers in Physiology 17 citations
Article Tier 2

Molecular responses to pollution stress in glass eels (Anguilla anguilla): Gene expression changes associated with varying contamination levels and temperature across estuaries

Researchers measured gene expression in European eel glass eels entering estuaries with varying levels of microplastic and heavy metal contamination, finding that pollution and temperature shifts alter stress-response and metabolic gene expression in ways that may impair survival.

2025 Aquatic Toxicology
Article Tier 2

Transcriptome wide analyses reveal intraspecific diversity in thermal stress responses of a dominant habitat‐forming species

Researchers examined transcriptome-wide diversity in how coral species respond to thermal stress, revealing intraspecific genetic variation that may influence resilience to warming oceans. The findings highlight the importance of genetic diversity within coral populations for predicting reef responses to climate change.

2023 Scientific Reports 11 citations
Article Tier 2

Revealing the Impact of Polystyrene Nanoplastics on Gill Tissues of the Intertidal Clam, Gafrarium Divaricatum (Gmelin, 1791) using Transcriptomics Approach

Researchers exposed intertidal clams to polystyrene nanoplastics and used transcriptomics to assess gill tissue impacts, finding 1,182 upregulated and 1,626 downregulated genes related to immune modulation, antioxidant defense, and apoptosis. Histopathological examination revealed structural damage to gill tissues including ciliary erosion, lamellae fusion, and lipofuscin accumulation. The study establishes a high-quality genomic resource for this clam species while demonstrating the ecotoxicological effects of nanoplastics on sessile marine bivalves.

2026 Marine Biotechnology
Article Tier 2

Image_5_Gill Transcriptomic Responses to Toxin-producing Alga Prymnesium parvum in Rainbow Trout.tif

This image file is supplementary material from a study on how toxic algae affect gene expression in rainbow trout gills, documenting molecular responses to harmful algal bloom exposure.

2021 Figshare
Article Tier 2

[Physiological and Ecological Response Characteristics and Transcriptomic Change Characteristics of Rice (Oryza sativa)Under Different Microplastic Stresses].

Researchers used transcriptomic analysis to characterize physiological and ecological response characteristics of an aquatic organism exposed to microplastic stress, identifying gene expression changes in pathways related to immune function, oxidative stress, and energy metabolism.

2025 PubMed
Article Tier 2

Differential Cell Metabolic Pathways in Gills and Liver of Fish (White Seabream Diplodus sargus) Coping with Dietary Methylmercury Exposure

Researchers investigated differential metabolic responses in the gills and liver of white seabream exposed to dietary methylmercury, revealing tissue-specific detoxification pathways and cellular stress responses that help explain how fish cope with chronic mercury exposure.

2023 Toxics 14 citations
Review Tier 2

The Next Generation Is Here: A Review of Transcriptomic Approaches in Marine Ecology

This review assessed transcriptomic approaches in marine ecology, highlighting how next-generation sequencing technologies are enabling researchers to address ecological questions including organism responses to environmental stressors at the molecular level.

2022 Frontiers in Marine Science 26 citations
Article Tier 2

Noncoding Variation and Transcriptional Plasticity Promote Thermal Adaptation in Oysters by Altering Energy Metabolism

Comparative genomic and transcriptomic analysis of two closely related oyster species from warm and cold environments found that noncoding sequence divergence and adaptive transcriptional plasticity underpin thermal adaptation, with warm-adapted oysters showing higher plasticity in energy metabolism genes that up-regulate ATP production and lipid catabolism in response to heat.

2021 Molecular Biology and Evolution 68 citations
Article Tier 2

Application of transcriptomic profiling to investigate the toxicity mechanisms caused by dietary exposure of nanoplastics in fish

Researchers used transcriptomic profiling to evaluate the impact of dietary nanoplastic exposure on European sea bass, finding changes in gene expression in intestinal tissue after 21 days of feeding with polystyrene nanoparticle-containing food. The study suggests that while no significant changes were observed in enzymatic stress markers, nanoplastics may trigger subtle molecular-level responses in the fish gut.

2023 Aquatic Toxicology 7 citations
Article Tier 2

Copper-Induced Ionoregulatory Disturbance, Histopathology, and Transcriptome Responses in Freshwater Mussel (Anodonta woodiana) Gills

Researchers investigated copper toxicity in the freshwater mussel Anodonta woodiana, finding that sublethal exposure caused ionoregulatory disturbance, gill histopathology, and significant transcriptomic changes related to stress response and immune function.

2023 Fishes 10 citations
Article Tier 2

Copper and Microplastic Exposure Affects the Gill Gene Expression of Common Carp During Saltwater Challenge

This study examined how combined copper and microplastic exposure affects gill gene expression in common carp, finding synergistic stress responses including upregulation of genes involved in oxidative stress defense and immune function.

2024 Science Journal of University of Zakho 1 citations
Article Tier 2

Distinguish the toxic differentiations between acute exposure of micro- and nano-plastics on bivalves: An integrated study based on transcriptomic sequencing

Researchers found that nanoplastics are more toxic than microplastics in mussels, causing severe inflammatory responses and greater oxidative stress, with transcriptomic analysis revealing contrasting gene expression patterns between the two particle sizes.

2022 Aquatic Toxicology 35 citations