Papers

20 results
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Article Tier 2

Ecological risks of combination of multiple pollutants at environmentally relevant concentrations: Insights from the changes in life history traits, gut microbiota, and transcriptomic responses in Daphnia magna

Researchers exposed Daphnia magna to a combination of 11 pollutants including microplastics, antibiotics, and heavy metals at environmentally relevant ng/L–μg/L concentrations and found significant reductions in heart rate, reproduction, and lifespan, plus gut microbiota and transcriptomic changes — effects that single-pollutant studies would not predict.

2025 Resources Environment and Sustainability
Article Tier 2

Combined effect of microplastics and tire particles on Daphnia magna: Insights from physiological and transcriptomic responses

Researchers investigated the combined effects of microplastics and tire particles on the water flea Daphnia magna, finding that the mixture triggered significant oxidative stress at environmentally relevant concentrations. Transcriptomic analysis revealed upregulation of antioxidant and metabolic stress genes, while energy reserves like glycogen were affected. The study suggests that co-exposure to these common freshwater pollutants may pose greater ecological risks than either particle type alone.

2025 Environmental Pollution 1 citations
Article Tier 2

Unleashing multi-omic approaches to address environmental microplastic hazards in marine polychaetes

Researchers used a multi-omic approach (metagenomics and metabolomics) to study how an environmental microplastic mixture affects the gut microbiome and metabolism of marine polychaetes, identifying disruption of specific bacterial taxa and altered metabolite profiles (indoles, flavonoids, terpenes) that indicate physiological stress.

2025 Marine Pollution Bulletin
Article Tier 2

Metabolomic analysis of combined exposure to microplastics and methylmercury in the brackish water flea Diaphanosoma celebensis

Combined exposure of the brackish water flea Diaphanosoma celebensis to microplastics and methylmercury produced metabolomic disruptions greater than either pollutant alone, with the combination altering amino acid metabolism, energy pathways, and oxidative stress markers. The study provides molecular-level evidence that microplastic-mercury co-contamination poses synergistic risks to aquatic invertebrates.

2022 Environmental Geochemistry and Health 14 citations
Article Tier 2

Effects of microplastics on Daphnia-associated microbiomes in situ and in vitro

This study investigated how microplastic exposure alters the microbiome associated with Daphnia in freshwater, finding shifts in bacterial community composition that may affect host health and ecological function. The results suggest that microplastics can indirectly harm zooplankton by disrupting their microbial symbionts.

2024
Article Tier 2

Combined Effects of Polystyrene Nanoplastics and Enrofloxacin on the Life Histories and Gut Microbiota of Daphnia magna

Researchers exposed Daphnia magna to polystyrene nanoplastics and the antibiotic enrofloxacin alone and in combination, measuring life history traits and gut microbiota responses. Both stressors individually reduced survival and reproduction, and combined exposure altered the taxonomic composition and metabolic function of gut microbiota more than either contaminant alone.

2022 Water 19 citations
Article Tier 2

Multi stress system: Microplastics in freshwater and their effects on host microbiota

This study examined how combined exposure to microplastics and organic chemical pollutants affects freshwater organisms through a multi-stress approach, focusing on gut microbiome changes as an indicator. Microplastic exposure in combination with other pollutants altered microbiome composition more than either stressor alone, with potential consequences for host fitness and disease resistance.

2022 The Science of The Total Environment 14 citations
Article Tier 2

Effects of microplastics on Daphnia -associated microbiomes in situ and in vitro

Researchers examined how microplastics affect the microbiome of Daphnia, a keystone freshwater organism, through both field sampling and controlled laboratory experiments. Using DNA sequencing techniques, they found that microplastic exposure altered the composition of bacterial communities associated with Daphnia. The study suggests that microplastic pollution may disrupt the beneficial microbial relationships that support the health of important freshwater species.

2024 The ISME Journal 3 citations
Article Tier 2

Transcriptional response provides insights into the effect of chronic polystyrene nanoplastic exposure on Daphnia pulex

RNA sequencing of Daphnia pulex after 21 days of polystyrene nanoplastic exposure identified 244 differentially expressed genes, with key downregulated genes involved in trehalose metabolism and chitin synthesis and upregulated genes involved in stress response pathways. The transcriptomic analysis reveals metabolic and immune disruption as central mechanisms of chronic nanoplastic toxicity in this keystone freshwater species.

2019 Chemosphere 125 citations
Article Tier 2

The effects of exposure to microplastics and pollutants on the arthropod microbiome

This thesis investigated how microplastics and other pollutants (pesticides, detergents, metals) affect the gut microbiome of freshwater invertebrates. Disruption of the host-microbiome relationship by microplastics could impair immune function and overall health in aquatic organisms that form important parts of the food web.

2021 Digital comprehensive summaries of Uppsala dissertations from the Faculty of Science and Technology
Article Tier 2

Polystyrene nanoplastic induces oxidative stress, immune defense, and glycometabolism change in Daphnia pulex: Application of transcriptome profiling in risk assessment of nanoplastics

Researchers used transcriptome sequencing to examine how polystyrene nanoplastics affect gene expression in the water flea Daphnia pulex. After 96 hours of exposure, they identified 208 genes with altered expression levels, linked to oxidative stress, immune defense, and sugar metabolism pathways. The study provides molecular-level evidence that nanoplastic pollution can trigger multiple stress responses in freshwater organisms.

2020 Journal of Hazardous Materials 167 citations
Article Tier 2

Nanoplastic-induced microbiome shifts reduce Daphnia fitness and increase parasite reproduction

This dataset contains data and R scripts from a study examining how nanoplastic exposure causes microbiome shifts in Daphnia that reduce host fitness and increase parasite reproduction. The research by Villegas, Rajarajan, and colleagues at the Leibniz Institute provides the underlying data supporting analysis of nanoplastic-microbiome-host-parasite interactions.

2025 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

The effects of environmental Microplastic on wharf roach (Ligia exotica): A Multi-Omics approach

Wild wharf roaches collected from a microplastic-contaminated South Korean shoreline had 50 times more plastic particles in their guts than roaches from a cleaner site, and the contaminated animals also carried elevated levels of brominated flame retardants leached from the polystyrene foam they had ingested. Gene expression analysis revealed that the contaminated roaches showed altered immune, metabolic, and stress-response pathways. Because wharf roaches are a key detritus-consuming species in coastal ecosystems, this study demonstrates that microplastic pollution can have cascading biological effects from the base of the food web.

2023 Chemosphere 11 citations
Article Tier 2

Microplastic Exposure Across Trophic Levels: Effects on the Host Microbiota of Freshwater Organisms

Researchers investigated how microplastic exposure affects the gut bacteria communities of freshwater organisms including fish, invertebrates, and crustaceans. Microplastics—particularly when combined with pesticides—altered gut microbiota composition, which could impair digestion, immunity, and overall health of freshwater species.

2021 1 citations
Article Tier 2

Metabolomics reveals the mechanism of polyethylene microplastic toxicity to Daphnia magna

Using metabolomics and traditional toxicology, researchers investigated how polyethylene microplastics of different sizes affect the water flea Daphnia magna. The study found that microplastic exposure disrupted amino acid metabolism, lipid metabolism, and energy pathways, with smaller particles generally causing more pronounced metabolic disturbances.

2022 Chemosphere 56 citations
Article Tier 2

Impact of a chronic waterborne exposure to polystyrene nanoplastics on the gilthead seabream (Sparus aurata): Combining traditional and multi-omics approaches

Researchers exposed gilthead seabream to environmentally relevant and elevated polystyrene nanoplastic concentrations for 28 days, finding no visible tissue damage or blood abnormalities but significant shifts in gut microbiome diversity and dose-dependent changes in plasma metabolites linked to energy metabolism, suggesting subtle long-term risks for aquaculture production.

2025 Journal of Hazardous Materials 1 citations
Article Tier 2

Effects of nanoplastic exposure on the immunity and metabolism of red crayfish (Cherax quadricarinatus) based on high-throughput sequencing

Researchers examined nanoplastic effects on red crayfish using transcriptomics and microbiome analysis, finding that high concentrations suppressed antioxidant and immune responses while significantly altering gut microbial communities.

2022 Ecotoxicology and Environmental Safety 25 citations
Article Tier 2

Nanoplastics diversify and reshape Daphnia microbiomes in parasite-infected and uninfected hosts

Scientists exposed water fleas (Daphnia magna) to polystyrene nanoplastics of two sizes, with and without a yeast parasite infection, and analyzed changes in their gut and body microbiomes. The smallest nanoplastics at the highest concentration caused the most dramatic shifts in bacterial communities, with effects that exceeded those caused by the parasite alone. The results suggest that nanoplastic pollution could fundamentally reshape the beneficial microbes that aquatic organisms depend on for their health.

2025 Environmental Pollution 2 citations
Article Tier 2

Impacts of microplastics and pesticides on Daphnia

Researchers investigated the combined and individual impacts of microplastics and pesticides on Daphnia magna, a model crustacean widely used in freshwater ecotoxicology, to assess how these co-occurring pollutants affect aquatic ecosystem health. The study examined survival, reproduction, and physiological responses in D. magna exposed to varying concentrations of both stressors under controlled conditions.

2025 Fisher Digital Publications (St. John Fisher College)
Article Tier 2

Comprehensive analysis of proteomic and biochemical responses of Daphnia magna to short-term exposure to polystyrene microplastic particles

Scientists exposed tiny freshwater crustaceans (Daphnia magna) to polystyrene microplastic particles for just 48 hours and found widespread disruptions at the molecular level. The organisms showed reduced energy metabolism, elevated signs of oxidative stress, and activated cellular uptake pathways, possibly as a defense mechanism. These findings indicate that even short-term microplastic exposure can trigger a complex stress response in a species that plays a key role in freshwater food webs.

2024 Ecotoxicology and Environmental Safety 4 citations