We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Papers
61,005 resultsShowing papers similar to Research trend on the emerging role of the microbiome in idiopathic male infertility
ClearGut microbiota is involved in male reproductive function: a review
This review summarizes how gut bacteria influence male reproductive health, including sperm quality, testicular health, sex hormone levels, and sexual behavior. The findings suggest that an unhealthy gut microbiome may contribute to male infertility, while probiotic supplements could potentially improve reproductive function -- an important connection as microplastics are known to disrupt gut bacteria.
Global trends and hotspots of gastrointestinal microbiome and toxicity based on bibliometrics
This bibliometric analysis mapped global research trends and hotspots in gastrointestinal microbiome and toxicity studies, finding that modifications to the gut microbiome could offer new directions for treating and mitigating toxic exposures.
Unraveling the Intricacies of the Seminal Microbiome and Its Impact on Human Fertility
This review explores the growing understanding of microbial communities found in seminal fluid and their potential role in male fertility. Researchers found that certain bacterial populations are associated with healthy reproductive function, while imbalances in these communities may correlate with fertility challenges. The study highlights the seminal microbiome as an emerging area of research that could lead to new approaches for understanding and addressing reproductive health.
Testis–Gut‐Reproduction Axis: The Key to Reproductive Health
This review explores the connection between gastrointestinal health and male reproductive function, describing a testis-gut-reproduction axis. Researchers found that gut hormones and gut microbiota can either promote or inhibit testicular functions including sperm production and hormone regulation. The study suggests that maintaining gut health may be an important factor in supporting male fertility.
Trends in Semen Quality: A Contrasting Perspective From a Single-Centre Review in Ireland.
Researchers analyzed 18,219 semen samples from 15,413 men attending a fertility clinic in Ireland between 2008 and 2023, finding a 22.8% increase in median sperm concentration over the period — contrasting with globally reported declining sperm quality trends and highlighting that fertility trajectories vary by region and population.
Targeting Modifiable Risks: Molecular Mechanisms and Population Burden of Lifestyle Factors on Male Genitourinary Health
This systematic review examines how lifestyle factors, including microplastic exposure, affect male reproductive health. Research shows that microplastics, along with other environmental contaminants, may contribute to declining sperm quality and male infertility, which now affects up to 50% of infertility cases worldwide.
Environmental determinants of male infertility: emerging threats and technological interventions
This review examines how environmental contaminants, including microplastics, air pollution, heavy metals, and endocrine-disrupting chemicals, may contribute to declining male fertility. The study suggests these environmental toxins can impair sperm function through oxidative stress, hormonal imbalance, and inflammation, and highlights the need for integrating environmental exposure data into fertility assessments.
Nexus Between Sarcopenia and Microbiome Research: A Bibliometric Exploration
Researchers conducted a bibliometric analysis of the intersection between sarcopenia and microbiome research, analyzing 997 articles from the Science Citation Index Extended Database to map scientific production, international collaboration networks, and emerging research hotspots in this growing field.
Quantitative analysis and toxicological mechanisms of various male infertility inducers: A network meta-analysis and pharmacological approach.
This network meta-analysis of 201 rodent studies compared nine common male infertility inducers, finding that microplastics caused among the most severe impairments to sperm count and motility — on par with the chemotherapy drug cyclophosphamide. Oxidative stress emerged as a shared mechanistic pathway across all inducers, pointing to it as a key target for understanding and potentially mitigating reproductive harm from environmental exposures.
Bibliometric and visual analysis of blood-testis barrier research
This bibliometric analysis of 942 publications on the blood-testis barrier identified key research themes, prolific authors, and emerging frontiers in the field from its inception through recent years. The analysis highlighted growing research into microRNA regulation of barrier integrity and environmental toxicant impacts on Sertoli cell function as future hotspots.
Environmental and microbiome determinants of sperm quality: a narrative review on male health
This narrative review examines how environmental factors, including microplastics and other emerging contaminants, affect male sperm quality and fertility. The study suggests that pollutants such as heavy metals, pesticides, phthalates, PFAS, air pollution, and microplastics can impair sperm parameters through various mechanisms, and highlights the role of the reproductive microbiome in mediating these environmental effects.
Oxidative Stress and Male Fertility: Promising Role of Nutraceuticals
This paper is not about microplastics; it reviews the role of oxidative stress in male infertility and the potential of nutraceuticals (antioxidant-rich dietary supplements) to improve sperm quality and hormonal profiles, with no connection to microplastic research.
What is driving the global decline of human fertility? Need for a multidisciplinary approach to the underlying mechanisms
This paper examines the many factors driving the worldwide drop in human fertility rates, including delayed childbearing, obesity, and environmental toxicants such as nanoplastics and air pollution that harm reproductive health. The authors warn that these trends could have devastating public health consequences for our species if the underlying causes are not addressed.
Microplastics May Be a Significant Cause of Male Infertility
This review examines the potential link between microplastic exposure and the decline in male fertility observed over recent decades. Researchers reviewed evidence showing that microplastics can accumulate in reproductive tissues and may damage sperm quality through oxidative stress, hormonal disruption, and inflammatory responses. The study suggests that microplastics deserve serious attention as a possible contributing factor to rising male infertility rates.
Impacto de los disruptores endocrinos derivados de plásticos en la regulación hormonal masculina: un análisis integral de la evidencia científica
This literature review compiled recent studies on how phthalates, bisphenol A, and microplastics from plastic products disrupt male hormonal regulation, finding evidence for reduced testosterone, impaired testicular synthesis, and alterations in the hypothalamic-pituitary-gonadal axis. The review calls for greater attention to plastic-derived endocrine disruptors in male reproductive health research.
A Bibliometric Analysis of Toxicological Impacts of Microplastics in the Environment.
This bibliometric analysis of microplastic toxicology research found exponential growth in gut health studies since 2016, highlighting rising concern over how microplastics — especially in combination with heavy metals — cause immunotoxicity, biofilm formation, and accumulation in human tissues.
Integrated fecal microbiome and metabolome analysis explore the link between polystyrene nanoplastics exposure and male reproductive toxicity in mice
Researchers exposed mice to polystyrene nanoplastics of different sizes and doses, then analyzed fecal microbiome and metabolome changes alongside reproductive outcomes. The study found that nanoplastic exposure disrupted gut microbiota balance and metabolic pathways, which correlated with reduced sperm count, viability, and testosterone levels. The findings suggest that gut microbiota-metabolite disruption may play an important role in nanoplastic-induced male reproductive toxicity.
Mapping the past, present and future research landscape of paternal effects
This review maps the scientific literature on paternal effects — how a father's environment and experiences can influence offspring health — using bibliometric analysis to identify research clusters. This paper is focused on evolutionary biology and epigenetics and is not directly related to microplastic research.
Climate change, microplastics, and male infertility
This brief commentary discusses how climate change and exposure to environmental pollutants, including microplastics and endocrine-disrupting chemicals, may be contributing to the documented decline in male fertility over recent decades. While the exact causes remain unknown, the authors highlight the need for more research into how these environmental factors affect reproductive health.
Male infertility and its link to microplastics: A sterile future
This review examines the link between microplastic exposure and male infertility, summarizing evidence that microplastics and their chemical additives disrupt reproductive hormones, sperm quality, and testicular function in animal models and human studies.
Microplastics and impaired male reproductive health—exploring biological pathways of harm: a narrative review
This narrative review summarizes the evidence that microplastics may harm male reproductive health through oxidative stress, hormone disruption, inflammation, and direct damage to reproductive cells. While animal studies show concerning effects on sperm quality, testicular function, and fertility, human studies are still lacking. The review calls for urgent research on microplastic impacts on human male fertility and for policies to reduce microplastic exposure.
Global trends and prospects in microplastics research: A bibliometric analysis
Researchers conducted a bibliometric analysis of global microplastics research using the Web of Science database from 1986 to 2019. The study found that publications on microplastics increased significantly since 2011, with research hotspots and trends shifting from marine contamination surveys toward understanding ecological impacts and human health implications.
Global Research Trends in Food Security: Insights from a Bibliometric Analysis
Researchers conducted a bibliometric analysis of over 500 publications on food security, revealing a significant increase in scholarly interest over the past decade. Key research themes included climate change, sustainable agriculture, and the intersection of food systems with environmental contaminants. The analysis maps the evolving landscape of food security research and identifies emerging areas of focus for future study.
Microplastics and male reproductive system: A comprehensive review based on cellular and molecular effects
This comprehensive review examines how microplastics affect the male reproductive system at cellular and molecular levels, drawing on studies from multiple scientific databases. Researchers found that microplastics can damage testicular structure and function, impair spermatogenesis, and disrupt sperm parameters through mechanisms including oxidative stress, inflammation, and activation of cell death pathways. The review highlights that microplastics reduce ATP production and trigger signaling cascades that may contribute to male fertility problems.