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Impacto de los disruptores endocrinos derivados de plásticos en la regulación hormonal masculina: un análisis integral de la evidencia científica
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This literature review compiled recent studies on how phthalates, bisphenol A, and microplastics from plastic products disrupt male hormonal regulation, finding evidence for reduced testosterone, impaired testicular synthesis, and alterations in the hypothalamic-pituitary-gonadal axis. The review calls for greater attention to plastic-derived endocrine disruptors in male reproductive health research.
Microplastics and their chemical constituents, such as phthalates and bisphenol A, have emerged as endocrine-disrupting agents capable of significantly altering the human hormonal system. This literature review compiles recent studies on the influence of such compounds on testosterone levels in males. It gathers evidence regarding the pathophysiological mechanisms underlying hormonal disruption, including interference with testicular synthesis and alterations in the hypothalamic-pituitary-gonadal axis. Clinical implications are discussed, including reduced fertility, muscle mass loss, and psychological effects. The review emphasizes the urgent need for stricter environmental regulations and public health education regarding daily exposure to plastic-derived chemicals. It concludes that chronic exposure to these pollutants represents an underestimated threat to male reproductive health, calling for increased clinical and scientific attention.
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From Prenatal Exposure to Adult Sexual Dysfunction: The Impact of Plastic-Derived Endocrine Disruptors on Testosterone Homeostasis and Erectile Function
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Everyday plastics — found in food packaging, containers, and countless consumer products — contain chemicals that can interfere with hormone signaling, and this review pulls together existing research suggesting they may lower testosterone and contribute to erectile dysfunction. The disruption seems to start as early as the womb, potentially affecting how the male reproductive system develops, and continues into adulthood by damaging blood vessels, promoting inflammation, and altering metabolism. While more research is needed to confirm direct cause-and-effect in humans, this is a good reminder to minimize plastic exposure where possible, especially around food and drink.
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