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Male infertility and its link to microplastics: A sterile future
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This review examines the link between microplastic exposure and male infertility, summarizing evidence that microplastics and their chemical additives disrupt reproductive hormones, sperm quality, and testicular function in animal models and human studies.
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This review examines the potential link between microplastic exposure and the decline in male fertility observed over recent decades. Researchers reviewed evidence showing that microplastics can accumulate in reproductive tissues and may damage sperm quality through oxidative stress, hormonal disruption, and inflammatory responses. The study suggests that microplastics deserve serious attention as a possible contributing factor to rising male infertility rates.
Microplastics and Fertility
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This paper reviews the growing body of evidence linking microplastic exposure to impaired human fertility, covering how microplastics and associated chemical additives can disrupt reproductive hormones and damage sperm and egg quality. It highlights the need for further research to establish dose-response relationships.
Microplastic Exposure and Male Infertility: Mechanisms, Effects on Semen Quality and Emerging Human Evidence
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This review summarizes research on tiny plastic particles found in human semen and testicular tissue. In rodent studies, exposure was linked to cell damage, hormone disruption, and reduced sperm count and quality; human studies show similar associations but are too limited to prove the particles cause male infertility.
The Impact of Microplastics on Male Fertility
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Microplastics and nanoplastics accumulate in testicular tissue and disrupt spermatogenesis through oxidative stress, inflammation, endocrine disruption, and structural damage to reproductive cells, consistently impairing sperm quality in experimental models. With global plastic production accelerating alongside documented declines in semen quality, this review highlights microplastic exposure as a plausible environmental contributor to male infertility warranting urgent human study.
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This narrative review summarizes the evidence that microplastics may harm male reproductive health through oxidative stress, hormone disruption, inflammation, and direct damage to reproductive cells. While animal studies show concerning effects on sperm quality, testicular function, and fertility, human studies are still lacking. The review calls for urgent research on microplastic impacts on human male fertility and for policies to reduce microplastic exposure.
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