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61,005 resultsShowing papers similar to Adverse health effects of emerging contaminants on inflammatory bowel disease
ClearPollutants, microbiota and immune system: frenemies within the gut
This review summarizes how environmental pollutants, including microplastics, disrupt the gut microbiome and immune system, potentially contributing to inflammatory bowel diseases and colorectal cancer. Pollutants reduce beneficial gut bacteria while promoting inflammation, weakening the intestinal barrier, and triggering a chain of events that can push cells toward cancerous growth.
Effects of microplastic and engineered nanomaterials on inflammatory bowel disease: A review
This review examines how microplastics and engineered nanomaterials affect people with inflammatory bowel disease, who may be especially vulnerable to these environmental particles. Researchers found that microplastics could worsen intestinal inflammation, while some nanomaterials shifted from mildly harmful to therapeutic effects depending on gut health status. The findings highlight the need for more research on how environmental particles affect people with pre-existing gut conditions.
The role of microplastics in the pathogenesis of inflammatory bowel diseases
This review of existing research found that tiny plastic particles we eat and drink may contribute to inflammatory bowel diseases like Crohn's disease and ulcerative colitis. The plastic bits can damage the gut lining, cause inflammation, and disrupt the healthy bacteria in our intestines. While more research is needed to confirm the connection, this suggests that reducing plastic pollution could be important for protecting our digestive health.
Research Advances on the Impact of Environmental Pollutants on Gut Microbiota
This review synthesizes evidence from animal models, human studies, and mechanistic experiments showing how microplastics, pesticides, and heavy metals each disrupt gut microbiota composition, reduce beneficial bacteria, and compromise intestinal barrier integrity and host health.
Effects of microplastics in aquatic environments on inflammatory bowel disease
Researchers reviewed current evidence on how microplastics found in aquatic environments may contribute to the occurrence and progression of inflammatory bowel disease (IBD). The study's analysis of in vitro and in vivo research suggests that prolonged exposure to microplastics through contaminated aquatic foods and drinking water may pose risks to intestinal health, though the relationship between microplastic exposure and IBD requires further investigation.
Raising the Alarm: Environmental Factors in the Onset and Maintenance of Chronic (Low-Grade) Inflammation in the Gastrointestinal Tract
This review examined how environmental factors including food additives, pesticides, microplastics, and other ubiquitous exposures can trigger chronic low-grade inflammation in the gastrointestinal tract, contributing to inflammatory bowel conditions through disrupted microbiota and epithelial barrier function.
Analysis\nof Microplastics in Human Feces Reveals a\nCorrelation between Fecal Microplastics and Inflammatory Bowel Disease\nStatus
Researchers found higher concentrations and greater diversity of microplastics in fecal samples from inflammatory bowel disease patients compared to healthy controls, suggesting a potential association between microplastic ingestion and gut inflammation, though causality remains to be established.
Micro- and nano-plastics, intestinal inflammation, and inflammatory bowel disease: A review of the literature
This review summarizes the growing evidence linking micro- and nanoplastic exposure to intestinal inflammation and inflammatory bowel disease (IBD). Studies show these tiny plastic particles can trigger immune responses in the gut, alter the gut microbiome, and worsen intestinal inflammation, though more research using standardized methods is needed to confirm these effects in humans.
Orally Ingested Micro- and Nano-Plastics: A Hidden Driver of Inflammatory Bowel Disease and Colorectal Cancer.
This review synthesizes evidence linking ingested micro- and nano-plastics to inflammatory bowel disease and colorectal cancer risk, proposing that microplastics act as a hidden driver of gut inflammation in vulnerable populations. The authors argue that intestinal accumulation of microplastics triggers immune and oxidative stress pathways that contribute to disease progression.
Impact of micro- and nanoplastics on gastrointestinal diseases: Recent advances
This review summarizes how micro- and nanoplastics can harm the digestive system by causing oxidative stress, inflammation, cell death, and disruption of gut bacteria. These connected pathways can damage the intestinal lining and may contribute to conditions like inflammatory bowel disease and colorectal cancer. The findings highlight the importance of understanding how everyday plastic exposure through food and water could affect gut health over time.
Exposure to polyethylene microplastics exacerbate inflammatory bowel disease tightly associated with intestinal gut microflora
This study found that polyethylene microplastics, one of the most common types found in everyday products, worsened inflammatory bowel disease symptoms by disrupting the gut microbiome. The microplastics changed the balance of gut bacteria in ways that increased intestinal inflammation. These findings suggest that swallowing microplastics through food and drinks could make existing bowel conditions worse or contribute to gut inflammation in otherwise healthy people.
A Comprehensive Narrative Review of Potential Gastrointestinal Adverse Effects From Micro(nano) Plastic Exposure
This narrative review synthesizes evidence on gastrointestinal adverse effects of micro- and nanoplastic exposure, examining how these particles interact with gut microbiota, mucosal barriers, and immune tissue to contribute to inflammatory bowel disease, liver disease, and colorectal cancer risk.
Interactions between gut microbiota and emerging contaminants exposure: new and profound implications for human health
This review explores how emerging contaminants like microplastics, antibiotics, and persistent organic pollutants interact with gut bacteria and what that means for human health. Researchers found that the gut microbiome is a key target of these pollutants and may play a role in organ damage, hormonal disruption, and other toxic effects through pathways like the gut-liver and gut-brain axes. The study underscores the importance of understanding the three-way relationship between environmental contaminants, gut bacteria, and overall health.
Micro- and Nanoplastics: A Paradigm Shift in the Pathogenesis of Inflammatory Bowel Disease
This review paper summarizes research showing that tiny plastic particles from food and water may contribute to inflammatory bowel disease (IBD), a painful condition affecting the digestive system. Early studies suggest these microscopic plastics can damage the gut lining and trigger inflammation, though more research is needed to prove they directly cause IBD. Since plastic exposure can potentially be reduced, understanding this connection could lead to new ways to prevent or treat digestive diseases.
Analysis of Microplastics in Human Feces Reveals a Correlation between Fecal Microplastics and Inflammatory Bowel Disease Status
Researchers analyzed microplastics in the stool of patients with inflammatory bowel disease (IBD) and healthy volunteers, finding that IBD patients had significantly higher concentrations of microplastics in their feces. PET plastic and polyamide were the most common types found, likely originating from food packaging and dust. The positive correlation between microplastic levels and IBD severity suggests that microplastic exposure may be linked to gut inflammation, though it is not yet clear whether the plastics contribute to the disease or the disease causes more plastic retention.
The potential influence of food additives and contaminants on the gut microbiota: A comprehensive review
This comprehensive review examines how food additives and contaminants, including pesticides, heavy metals, microplastics, and antibiotics, affect the gut microbiota. Researchers found that these substances can disrupt the balance of gut microbes, leading to inflammation, gastrointestinal injury, and altered production of beneficial short-chain fatty acids. The study emphasizes the need for further research into the mechanisms by which dietary contaminants affect gut health and overall wellbeing.
Intestinal permeability, food antigens and the microbiome: a multifaceted perspective
This review summarizes how a leaky gut barrier, caused by factors like Western diets, pollution, and infections, can trigger chronic diseases including celiac disease, food allergies, and irritable bowel syndrome. The gut lining, microbiome, and immune system all work together to maintain health, but environmental disruptions can throw this balance off. This is relevant to microplastics research because studies have shown that microplastic exposure can damage the gut barrier and alter the microbiome in similar ways.
Interactions between environmental pollutants and gut microbiota: A review connecting the conventional heavy metals and the emerging microplastics
This review examines how environmental pollutants, including both heavy metals and microplastics, interact with gut bacteria in humans and animals. The authors found that these pollutants can disrupt the balance of gut microbiota, which may contribute to various health problems, and that gut bacteria can also transform pollutants in ways that change their toxicity.
Toxicological Evaluation of Effects of Some Environmental Pollutants on Intestinal Microbiota: Traditional Review
This review examines how various environmental pollutants affect the gut microbiome — the community of microorganisms in the intestinal tract. Microplastics are among the pollutants discussed, and their ability to alter gut microbiota composition is increasingly recognized as a mechanism by which plastic particles may harm human and animal health.
Micro(nano)plastics in food system: potential health impacts on human intestinal system.
This review assessed how micro(nano)plastics in the human food system reach the intestine and accumulate in the gut, summarizing evidence that they can alter intestinal barrier function, trigger inflammation, and disrupt the gut microbiome, with implications for long-term digestive health.
Microplastics and the gut microbiome: Emerging health concerns and strategies
This review covers how microplastic ingestion affects the gut microbiome, describing mechanisms by which microplastics cause intestinal disorders, disrupt endocrine function, and promote pathogenic bacterial growth, while also noting inhalation and dermal absorption as secondary exposure routes.
Immunotoxicity and intestinal effects of nano- and microplastics: a review of the literature
This review examines the evidence on how nano- and microplastics affect the immune system and intestinal health. The findings suggest that exposure to these particles can disrupt the gut microbiome and impair critical intestinal barrier functions, potentially contributing to the development of chronic inflammatory and immune conditions.
Microplastics and human health: unveiling the gut microbiome disruption and chronic disease risks
This review summarizes evidence that microplastics disrupt the gut microbiome, the community of bacteria in our digestive system that plays a key role in immunity, metabolism, and overall health. By altering gut bacteria balance and triggering inflammation, microplastic exposure may contribute to chronic conditions including inflammatory bowel disease, metabolic disorders, and potentially even neurological problems through the gut-brain connection.
Exposure to Environmental Pollutants and Risk of Diarrhea: A Systematic Review
This systematic review summarizes existing research linking environmental pollutants, including microplastics, to increased risk of diarrhea and other gut problems. The study found that contaminants like pesticides, heavy metals, and microplastics in water and food can disrupt the digestive system, particularly in low-income countries with less water treatment. This highlights how microplastic-contaminated water may contribute to gastrointestinal health issues.