Papers

20 results
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Article Tier 2

Two genes related to reproductive development in the juvenile prawn, Macrobrachium nipponense: Molecular characterization and transcriptional response to nanoplastic exposure

Nanoplastic exposure altered the expression of two genes involved in reproductive development in juvenile freshwater prawns (Macrobrachium nipponense), suggesting that nanoplastics may disrupt reproductive pathways in crustaceans at low concentrations.

2021 Chemosphere 17 citations
Article Tier 2

Effects of nanoplastic exposure on the growth performance and molecular characterization of growth-associated genes in juvenile Macrobrachium nipponense

Researchers found that polystyrene nanoplastic exposure impaired growth in juvenile shrimp by damaging the hepatopancreas, disrupting digestive enzyme activity, and altering growth-related gene expression at concentrations above 10 mg/L.

2022 Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology 22 citations
Article Tier 2

Effects of nanoplastics on energy metabolism in the oriental river prawn (Macrobrachium nipponense)

Oriental river prawns exposed to polystyrene nanoplastics (5–40 mg/L) for up to 28 days showed concentration- and time-dependent decreases in survival and energy metabolism, including disrupted glycogen and triglyceride content, reduced metabolic enzyme activity, and altered gene expression of energy pathways.

2020 Environmental Pollution 110 citations
Article Tier 2

Polystyrene nanoplastics decrease molting and induce oxidative stress in adult Macrobrachium nipponense

Researchers found that polystyrene nanoplastics significantly decreased molting frequency and induced oxidative stress in adult freshwater prawns, with effects on antioxidant enzyme activities observed at environmentally relevant concentrations.

2022 Fish & Shellfish Immunology 37 citations
Article Tier 2

Change in energy-consuming strategy, nucleolar metabolism and physical defense in Macrobrachium rosenbergii after acute and chronic polystyrene nanoparticles exposure

Researchers examined how polystyrene nanoplastic exposure affects freshwater prawns over both short-term and long-term periods, finding significant changes in gene expression related to energy metabolism and physical defense. The study revealed that nanoplastic exposure disrupted nucleolar metabolism and triggered shifts in energy-consuming strategies, suggesting these particles pose a meaningful threat to aquatic crustaceans.

2023 Aquatic Toxicology 12 citations
Article Tier 2

Polystyrene nanoplastics induce apoptosis, histopathological damage, and glutathione metabolism disorder in the intestine of juvenile East Asian river prawns (Macrobrachium nipponense)

Researchers exposed juvenile East Asian river prawns to different concentrations of polystyrene nanoplastics for 28 days. They found that nanoplastic exposure caused intestinal cell death, tissue damage, and disrupted the glutathione antioxidant system in a dose-dependent manner. The study suggests that nanoplastic pollution in freshwater environments could significantly compromise the intestinal health and immune defenses of crustaceans.

2024 The Science of The Total Environment 5 citations
Article Tier 2

Effects of nanoplastics on antioxidant and immune enzyme activities and related gene expression in juvenile Macrobrachium nipponense

Researchers explored the effects of nanoplastics on survival, antioxidant activity, immune enzyme activity, and gene expression in juvenile oriental river prawns. The study found that increasing nanoplastic concentrations suppressed antioxidant and immune enzyme activities while altering related gene expression levels, indicating that nanoplastic exposure can compromise the defense systems of freshwater crustaceans.

2020 Journal of Hazardous Materials 195 citations
Article Tier 2

Transcriptomic analysis following polystyrene nanoplastic stress in the Pacific white shrimp, Litopenaeus vannamei

Researchers used transcriptomic analysis to study how polystyrene nanoplastics affect gene expression in Pacific white shrimp. They found that nanoplastic exposure activated lysosome pathways and disrupted genes involved in immune response, protein processing, and metabolism. The study provides molecular-level evidence that nanoplastics can interfere with multiple biological systems in commercially important shrimp species.

2023 Fish & Shellfish Immunology 15 citations
Article Tier 2

Transcriptomic analysis reveals nanoplastics-induced apoptosis, autophagy and immune response in Litopenaeus vannamei

Shrimp exposed to polystyrene nanoplastics for 28 days showed dose-dependent damage to their immune systems, including increased cell death, tissue destruction in the liver-like organ, and disrupted antioxidant defenses. At high concentrations, the nanoplastics overwhelmed the shrimp's ability to fight off threats. Since shrimp are an important food source, these findings raise concerns about the quality and safety of seafood from nanoplastic-contaminated waters.

2024 The Science of The Total Environment 10 citations
Article Tier 2

Effects of nanoplastic on cell apoptosis and ion regulation in the gills of Macrobrachium nipponense

Researchers exposed juvenile oriental river shrimp to varying concentrations of nanoplastics and examined effects on gill cell viability and ion regulation. They found that higher nanoplastic concentrations increased cell death rates, decreased ion content, reduced ATPase enzyme activity, and disrupted ion transport gene expression in gill tissues. The study suggests that nanoplastic pollution can impair critical ion regulation functions in freshwater crustaceans, with implications for aquaculture.

2022 Environmental Pollution 51 citations
Article Tier 2

Sequencing data of Amphiprion ocellaris (clownfish) exposed to polystyrene nanoplastic

Researchers exposed clownfish to polystyrene nanoplastics at environmentally relevant and high concentrations for seven days and performed biochemical and transcriptomic analyses. The study found that even low-concentration exposure triggered significant gene expression changes indicating energy reallocation and stress responses, while high concentrations amplified these effects and activated additional inflammatory and detoxification pathways.

2026 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

Sequencing data of Amphiprion ocellaris (clownfish) exposed to polystyrene nanoplastic

Researchers exposed clownfish to polystyrene nanoplastics at environmentally relevant and high concentrations for seven days and performed biochemical and transcriptomic analyses. The study found that even low-concentration exposure triggered significant gene expression changes indicating energy reallocation and stress responses, while high concentrations amplified these effects and activated additional inflammatory and detoxification pathways.

2026 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

Effects of Microplastics, Polystyrene, and Polyethylene on Antioxidants, Metabolic Enzymes, HSP-70, and Myostatin Expressions in the Giant River Prawn Macrobrachium rosenbergii: Impact on Survival and Growth

Researchers exposed juvenile giant river prawns (Macrobrachium rosenbergii) to polystyrene microspheres and polyethylene microparticles and found that both types reduced survival and growth while increasing oxidative stress markers and altering expression of heat shock proteins and myostatin, with polystyrene causing more severe effects.

2021 Archives of Environmental Contamination and Toxicology 34 citations
Article Tier 2

Acute and chronic effects of polystyrene microplastics on brine shrimp: First evidence highlighting the molecular mechanism through transcriptome analysis

Researchers investigated both acute and chronic toxicity of polystyrene microplastics on brine shrimp, using transcriptome analysis to uncover molecular mechanisms. While acute exposure did not significantly affect survival, chronic exposure led to concentration-dependent bioaccumulation and increased reactive oxygen species generation, with gene expression analysis revealing disrupted metabolic and stress response pathways.

2020 Journal of Hazardous Materials 176 citations
Article Tier 2

Ecotoxicological effects of polystyrene nanoplastics on common carp: Insights into blood parameters, DNA damage, and gene expression

Exposing common carp to polystyrene nanoplastics caused significant DNA damage in blood and brain cells, along with changes in genes related to immune function and stress response. Higher concentrations led to more severe effects, and the nanoplastics also disrupted liver antioxidant defenses. Since carp are widely consumed fish, these findings raise questions about the safety of fish from nanoplastic-contaminated waters for human consumption.

2024 Journal of Applied Toxicology 14 citations
Article Tier 2

Effects of microplastics on gene expression to nonspecific immune system in pacific white shrimp (Litopenaeus vannamei).

This study found that high-density polyethylene microplastic particles in shrimp feed suppressed immune defense genes in Pacific white shrimp and caused intestinal and gill tissue damage at concentrations well below lethal levels. The findings suggest that microplastic exposure could compromise immune function and health in farmed crustaceans.

2022 1 citations
Article Tier 2

Toxicokinetics of microplastics in Macrobrachium nipponense and their impact on the bioavailability of loaded pollutants

Researchers studied the toxicokinetics of microplastics in the freshwater prawn Macrobrachium nipponense, tracking uptake, distribution, and clearance across tissues and examining impacts on antioxidant defenses and immune function.

2024 Journal of Hazardous Materials 5 citations
Article Tier 2

Molecular effects of polystyrene nanoplastics toxicity in zebrafish embryos (Danio rerio)

Researchers exposed zebrafish embryos to polystyrene nanoplastics at various concentrations and measured gene expression changes related to stress, inflammation, and DNA repair. They found dose-dependent activation of oxidative stress and apoptotic pathways at the highest concentration, along with inhibition of the neurotransmitter-related gene acetylcholinesterase and DNA repair genes. The study suggests that nanoplastic exposure at the molecular level may compromise cellular defense mechanisms and neurological function in developing fish.

2022 Chemosphere 45 citations
Article Tier 2

The involvement of oxidative stress mediated endoplasmic reticulum pathway in apoptosis of Golden Pompano (Trachinotus blochii) liver under PS-MPs stress

Researchers exposed golden pompano, a commercially important marine fish in China, to polystyrene microplastics at three concentrations for 14 days and observed slowed growth and significant liver damage. The microplastics induced oxidative stress and triggered endoplasmic reticulum-mediated apoptosis in liver cells. The study provides evidence that coastal aquaculture species face real toxicological risks from microplastic pollution in their farming environments.

2022 Ecotoxicology and Environmental Safety 63 citations
Article Tier 2

Integrated transcriptomic and metabolomic analyses to decipher the regulatory mechanisms of polystyrene nanoplastic-induced metabolic disorders in hepatocytes

Using combined transcriptomic and metabolomic analysis, this study found that polystyrene nanoplastics disrupt lipid and amino acid metabolism in hepatocytes, identifying key regulatory genes and providing data relevant to assessing health risks from nanoplastic exposure.

2025 Environmental Science Nano