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61,005 resultsShowing papers similar to Ferrous Ion Alleviates Lipid Deposition and Inflammatory Responses Caused by a High Cottonseed Meal Diet by Modulating Hepatic Iron Transport Homeostasis and Controlling Ferroptosis in Juvenile Ctenopharyngodon idellus
ClearSeasonal assessment of selected trace elements in grass carp (Ctenopharyngodon idella) blood and their effects on the biochemistry and oxidative stress markers
Researchers monitored trace metal concentrations in the blood of grass carp across seasons and found significant seasonal differences, along with statistical links between metals like zinc, iron, and copper and markers of liver function, oxidative stress, and metabolism. The findings show that environmental metal pollution has measurable physiological effects on freshwater fish, which are continuously exposed through their aquatic habitat.
Ameliorative Hematological and Histomorphological Effects of Dietary Trigonella foenum-graecum Seeds in Common Carp (Cyprinus carpio) Exposed to Copper Oxide Nanoparticles
Researchers tested dietary fenugreek seed extract as a protective supplement in common carp exposed to copper oxide nanoparticles at 1.5 mg per liter. Fenugreek supplementation at 125-150 mg per liter reduced hematological toxicity and improved tissue histomorphology in fish exposed to CuO nanoparticles, suggesting potential as a nutraceutical mitigation strategy.
Nano Iron Versus Bulk Iron Forms as Functional Feed Additives: Growth, Body Indices, Hematological Assay, Plasma Metabolites, Immune, Anti-oxidative Ability, and Intestinal Morphometric Measurements of Nile tilapia, Oreochromis niloticus
Researchers compared the effects of feeding Nile tilapia fish diets supplemented with regular iron oxide versus nano-sized iron oxide particles. Fish fed the nano-iron at higher concentrations showed the best growth performance, stronger immune responses, better antioxidant protection, and healthier intestinal structure. The study suggests that nano-sized iron supplements may be more efficiently absorbed and utilized by fish compared to conventional bulk iron forms.
Co-exposure of decabromodiphenyl ethane and polystyrene nanoplastics damages grass carp (Ctenopharyngodon idella) hepatocytes: Focus on the role of oxidative stress, ferroptosis, and inflammatory reaction
Researchers found that combined exposure of grass carp liver cells to polystyrene nanoplastics and the flame retardant DBDPE triggered stronger oxidative stress, iron overload-mediated cell death (ferroptosis), and inflammatory cytokine release than either pollutant alone, with the ferroptosis inhibitor ferrostatin-1 partially reversing the damage.
Dietary silymarin, Silybum marianum extract ameliorates cadmium chloride toxicity in common carp, Cyprinus carpio
Supplementing the diet of common carp with silymarin extract protected fish from cadmium chloride toxicity, with treated fish showing reduced liver damage, lower oxidative stress markers, and better growth performance compared to cadmium-exposed controls without the supplement.
Evidence of Microplastics in Gut Content of Grass Carp (Ctenopharyngodon idella) Fingerlings and their Effects on Growth Performance and Body Composition
Grass carp (Ctenopharyngodon idella) fingerlings were fed diets containing 1-9% biodegradable microplastics for 60 days to assess effects on growth performance, body composition, nutrient digestibility, and gut microplastics content. The study found microplastic contamination in gut contents across all treatment groups, with dose-dependent effects on fish health metrics.
The effects of exposure to microplastics on grass carp (Ctenopharyngodon idella) at the physiological, biochemical, and transcriptomic levels
Researchers exposed grass carp to microplastics at two concentrations for 21 days and observed liver damage, inhibited growth, and increased oxidative stress. Transcriptome analysis revealed over 1,500 differentially expressed genes related to immune response, metabolism, and cellular stress pathways. The study suggests that microplastic exposure can trigger broad physiological and molecular disruptions in freshwater fish.
Dietary Arthrospira platensis in Rainbow Trout (Oncorhynchus mykiss): A Means to Reduce Threats Caused by CdCl2 Exposure?
Researchers investigated whether dietary Spirulina supplementation could protect rainbow trout from cadmium chloride toxicity, evaluating growth performance, immune response, and tissue damage to assess its potential as a protective feed additive in aquaculture.
The Importance of Fatty Acid Precision Nutrition: Effects of Dietary Fatty Acid Composition on Growth, Hepatic Metabolite, and Intestinal Microbiota in Marine Teleost Trachinotus ovatus
Researchers fed pomfret juveniles three diets with different fatty acid compositions including fish oil, a custom blend oil, and a fish-soybean oil blend and found that the custom blend oil diet matched fish oil for growth while reducing liver inflammation, oxidative stress markers, and pathogenic gut bacteria, supporting precision lipid nutrition in marine aquaculture.
Microplastics induced inflammation and apoptosis via ferroptosis and the NF-κB pathway in carp
Researchers exposed carp to polyethylene microplastics and found they caused serious intestinal damage through two harmful pathways: ferroptosis (a type of iron-dependent cell death) and NF-kB-driven inflammation. The microplastics triggered a buildup of iron and reactive oxygen species in gut tissue, leading to cell death and tissue destruction. Since humans also ingest microplastics that reach the gut, these findings highlight a potential mechanism by which microplastics could damage our digestive system.
Peroxisome Proliferator-Activated Receptor Signaling-Mediated 13-S-Hydroxyoctadecenoic Acid Is Involved in Lipid Metabolic Disorder and Oxidative Stress in the Liver of Freshwater Drum, Aplodinotus grunniens
Researchers investigated how high-fat diets cause lipid deposition and metabolic disorders in the liver of freshwater drum fish. The study identified PPAR-mediated 13-S-hydroxyoctadecenoic acid as a key regulatory target linking lipid metabolism dysfunction to oxidative stress, and found that restricting lipid intake could reverse these harmful effects.
Enhanced Immune Response Improves Resistance to Cadmium Stress in Triploid Crucian Carp
This study found that triploid crucian carp exhibit enhanced immune responses compared to diploid fish, which may contribute to their greater resistance to cadmium-induced stress.
Unveiling the Effects of Fennel (Foeniculum vulgare) Seed Essential Oil as a Diet Supplement on the Biochemical Parameters and Reproductive Function in Female Common Carps (Cyprinus carpio)
Researchers investigated the effects of fennel seed essential oil on the health and reproductive function of common carp over 60 days. At lower doses, the oil improved growth rates and immune parameters, while the highest dose elevated stress-related enzyme levels. The study suggests that fennel oil at moderate doses could serve as a beneficial dietary supplement for farmed fish.
Ferroptosis and hepatic fibrosis induced by cooperative exposure to polylactic acid nanoplastics and copper: Emphasis on gut microbiota dysbiosis
Researchers investigated the combined hepatotoxicity of polylactic acid nanoplastics and copper in mice, focusing on the gut-liver axis. The study found that co-exposure caused synergistic liver damage through ferroptosis, characterized by disrupted glutathione and iron homeostasis, along with gut microbiota dysbiosis and hepatic fibrosis more severe than either pollutant alone.
Supplementary Feed Potential on Histology and Immune Response of Tilapia (Oreochromis niloticus L.) Exposed to Microplastics
Researchers found that supplementing tilapia feed with probiotics or vitamin C significantly mitigated microplastic-induced organ damage, reducing liver necrosis and inflammation markers while improving intestinal structure and immune cytokine balance.
Effect of dietary cinnamon supplementation on the growth in length, haematology, serum biochemistry, intestinal microbiota and enzymes and histomorphological changes of the intestine, liver and the kidney of Heteroclarias (Clarias gariepinus ♀ × Heterobra ♂)
Dietary cinnamon supplementation at 1-2% significantly improved growth, blood parameters, antioxidant enzyme activity, and intestinal health in juvenile catfish over a 56-day trial. The spice enhanced beneficial gut microbiota while reducing pathogenic bacteria, suggesting cinnamon as a natural feed additive for aquaculture.
Deciphering the gut microbiome of grass carp through multi-omics approach
This multi-omics study profiled the gut microbiome, transcriptome, and metabolome of grass carp to identify microbial species and metabolic pathways that support host metabolism and immunity, providing a foundation for developing microbiome-targeted feed additives as antibiotic alternatives in aquaculture.
Effect of Scoparia dulcis Extract on Lipid Oxidation in Fish Feed, Growth Performance, and Hypoxia Tolerance in Juvenile Jian Carp (Cyprinus carpio var. Jian)
This paper is not relevant to microplastics research; it investigates the effects of Scoparia dulcis plant extracts on lipid oxidation in fish feed and growth performance in Jian carp, focusing on antioxidant and digestive outcomes.
Scruitinizing the Effects of Microplastic (Polyethylene) on Minerals and Liver Enzyme Profile Of Common Carp (Cyprinus carpio)
Researchers exposed common carp to polyethylene microplastics at three concentrations over 7 and 14 days and measured changes in blood minerals and liver enzymes. They found dose- and time-dependent increases in liver damage markers and significant ionic imbalances, including consistent drops in potassium levels. The study suggests that even short-term microplastic exposure can disrupt fish liver function and the ability to maintain proper electrolyte balance.
Single and combined effects of microplastics and cadmium on juvenile grass carp (Ctenopharyngodon idellus)
Researchers found that combined exposure to polystyrene microplastics and cadmium in juvenile grass carp caused greater physiological stress than either pollutant alone, with microplastics enhancing cadmium accumulation and intensifying oxidative stress and immune responses.
Effects of the use of synthetic astaxanthin in the feeding of Lophiosilurus alexandri, a neotropical siluriform fish
Researchers found that feeding synthetic astaxanthin to Lophiosilurus alexandri juveniles at 100 mg/kg inclusion level resulted in optimal carotenoid retention in tissues without significantly affecting growth, blood biochemistry, or liver histology.
Evaluation of the Effect of Dietary Manganese on the Intestinal Digestive Function, Antioxidant Response, and Muscle Quality in Coho Salmon
This paper is not relevant to microplastics research; it investigates the effects of dietary manganese levels on intestinal digestive function, antioxidant response, and muscle quality in coho salmon.
Transcriptome analysis provides insights into copper toxicology in piebald naked carp (Gymnocypris eckloni)
Researchers exposed piebald naked carp to copper — a common water pollutant — and found it significantly disrupted gene activity in the gills and liver, particularly genes involved in building proteins, suggesting that fish respond to metal-induced stress by broadly slowing down protein production as a protective mechanism.
Subchronic Exposure to Microcystin-LR Induces Hepatic Inflammation, Oxidative Stress, and Lipid Metabolic Disorders in Darkbarbel Catfish (Tachysurus vachelli)
Researchers exposed catfish to microcystin-LR, a common water pollutant produced by algal blooms, and found it caused significant liver inflammation, oxidative stress, and disrupted fat metabolism over 28 days. The toxin triggered immune cell infiltration in the liver and altered the expression of genes involved in lipid processing. The study provides evidence that even environmentally relevant concentrations of this algal toxin can cause serious liver damage in freshwater fish.