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61,005 resultsShowing papers similar to Innovations in minimally invasive gynecologic surgery: Benefits and challenges
ClearAdverse effects of microplastics and nanoplastics on the reproductive system: A comprehensive review of fertility and potential harmful interactions
This review summarizes how microplastics and nanoplastics can harm both male and female reproductive systems by disrupting hormone signaling, damaging sperm and egg cells, and causing inflammation in reproductive tissues. Smaller nanoplastics are especially concerning because they can cross biological barriers more easily and reach the testes and ovaries. With global infertility rates rising, the authors highlight environmental plastic exposure as a factor that deserves more research attention.
"Unseen Dangers: The Effects of Micro- and Nanoplastics on Human Reproductive Health - A Narrative Review"
This review examines the effects of micro- and nanoplastics on human reproductive health, covering evidence from in vitro, animal, and epidemiological studies showing that plastic particles can disrupt hormone signaling, sperm function, ovarian development, and placental integrity.
Environmental determinants of male infertility: emerging threats and technological interventions
This review examines how environmental contaminants, including microplastics, air pollution, heavy metals, and endocrine-disrupting chemicals, may contribute to declining male fertility. The study suggests these environmental toxins can impair sperm function through oxidative stress, hormonal imbalance, and inflammation, and highlights the need for integrating environmental exposure data into fertility assessments.
Microplastics and Fertility
This paper reviews the growing body of evidence linking microplastic exposure to impaired human fertility, covering how microplastics and associated chemical additives can disrupt reproductive hormones and damage sperm and egg quality. It highlights the need for further research to establish dose-response relationships.
Secular changes in human reproduction and assisted reproductive technologies
This demographic review examines trends in human fertility and infertility over recent decades, noting that while child survival has improved, infertility affects about 15% of couples worldwide. The paper reviews assisted reproductive technologies as a response to this trend. While not directly about microplastics, there is growing evidence that microplastic exposure is one factor contributing to declining reproductive function in both men and women.
Microplastics and endocrine disruption: Emerging risks for human fertility
This short communication reviewed emerging evidence that microplastics and nanoplastics disrupt endocrine function and reproductive health, highlighting effects on hormonal regulation, gametogenesis, and fertility outcomes. The authors called for more epidemiological studies to establish links between human microplastic exposure and fertility decline.
Toxicological effects of micro/nano-plastics on human reproductive health: A review
This review summarizes research on how micro- and nanoplastics affect human reproductive health in both men and women. Evidence from animal and lab studies shows that these particles can accumulate in reproductive organs, disrupt hormones, damage eggs and sperm, and cause inflammation and oxidative stress. While human studies are still limited, the growing body of evidence suggests that microplastic exposure is a potential threat to fertility that warrants further investigation.
A review of the impact of micro‐ and nanoplastics on female reproduction: What we know and gaps in knowledge
This review examines what is known about how micro- and nanoplastics affect female reproductive health. Animal studies show these particles accumulate in ovarian tissue, disrupt hormones, and cause oxidative stress, leading to hormonal imbalances and ovarian damage, though research in humans is still limited.
Understanding the impact of nanoplastics on reproductive health: Exposure pathways, mechanisms, and implications
This review summarizes existing research on how nanoplastics (tiny plastic particles smaller than one micrometer) affect reproductive health in animals and potentially humans. Studies show that nanoplastics can accumulate in reproductive organs including the placenta, and evidence from animal studies links exposure to hormone disruption, reduced fertility, and developmental problems. The authors highlight a significant knowledge gap about nanoplastic effects on human reproduction, despite growing evidence that these particles reach our reproductive systems.
Male infertility and its link to microplastics: A sterile future
This review examines the link between microplastic exposure and male infertility, summarizing evidence that microplastics and their chemical additives disrupt reproductive hormones, sperm quality, and testicular function in animal models and human studies.
Microplastics and gynecological tumors: An emerging environmental health concern
This review examines the emerging connection between microplastic exposure and gynecological tumors. Evidence indicates that plastic additives like phthalates and bisphenol A are linked to increased risk of reproductive cancers, and microplastics themselves have been detected directly in human reproductive tissues. The study highlights a growing body of research suggesting that microplastics may contribute to tumor development through hormonal disruption, inflammation, and oxidative stress.
The emerging risk of microplastics and nanoplastics on the microstructure and function of reproductive organs in mammals: A systematic review of preclinical evidence
Preclinical evidence from 12 studies shows micro- and nanoplastics accumulate in mammalian gonads, causing dose-dependent damage including seminiferous degeneration, sperm malformation, reduced follicular growth, and impaired hormone levels through pro-oxidant and pro-inflammatory mechanisms.
Plastic Particles and Female Fertility: Pathways, Toxicity, and Analytical Challenges
This review examines the pathways, toxicity mechanisms, and analytical challenges associated with microplastic and nanoplastic impacts on female fertility. Evidence from animal studies indicates that these particles can accumulate in ovaries and placental tissue, inducing oxidative stress, inflammation, and granulosa cell death that diminishes ovarian reserve. The study notes that microplastics have been confirmed in human placentas and umbilical cord blood, and may disrupt the hormonal axis governing reproduction.
Size- and hydrophobicity-dependent accumulation of microplastics in follicular fluid is linked to impaired ovarian reserve in women undergoing medically assisted reproduction
Researchers measured microplastic concentrations in follicular fluid and blood from women undergoing fertility treatment and found that nearly all samples contained microplastics. Higher microplastic concentrations in follicular fluid were significantly associated with reduced oocyte yield and lower odds of pregnancy, with evidence suggesting that certain hydrophobic polymers selectively accumulate in the ovary.
The role of environmental toxins in infertility: Insights from cutting-edge research
Researchers reviewed the effects of environmental toxins including bisphenol A, pesticides, heavy metals, microplastics, and electromagnetic fields on human fertility. The study found that these substances have been linked to both male and female infertility through various mechanisms, and highlights the need for greater awareness and regulatory action to reduce exposure to these reproductive toxicants.
Exposição De Microplásticos E Nanoplásticos Ao Tecido Ovariano: Uma Revisão Integrativa
This integrative review examines the impact of micro- and nanoplastics on female ovarian tissue, synthesizing animal model studies showing damage to follicular structures, increased oxidative stress, and disrupted reproductive hormone signaling.
Threats of nano/microplastics to reproduction and offspring: Potential mechanisms and perspectives
This review summarized the evidence on how nano- and microplastics threaten reproduction and offspring health across multiple species, including fish, invertebrates, and mammals. The authors outlined potential mechanisms by which these plastic particles disrupt endocrine function, gonadal development, and embryonic development.
Microplastics in ovarian function and ozone-based mitigation strategies: Emerging evidence and translational implications
This review synthesized emerging evidence that microplastics accumulate in human follicular fluid, oocytes, placenta, and semen, causing oxidative stress, mitochondrial dysfunction, and meiotic disruption in reproductive cells, and discussed ozone-based strategies as potential mitigation approaches.
Plastics and its effect to women reproductive systems
This article reviews how plastic pollution, including microplastics and the hormone-disrupting chemicals they contain, may affect women's reproductive health. It connects widespread plastic use to endocrine disruption, menstrual irregularities, and fertility concerns, though much of the evidence comes from laboratory and animal studies.
Disruptors on Male Reproduction – Emerging Risk Factors
This review of emerging risk factors for male infertility covers endocrine-disrupting chemicals, heavy metals, pesticides, radiation, and pharmaceuticals, including a section on microplastics and the plastic-associated chemicals that have been linked to hormonal disruption and reduced sperm quality. While microplastics are one of several disruptors discussed rather than the sole focus, the paper is relevant because it places microplastic exposure within the broader context of the global decline in sperm counts and male reproductive health over recent decades.
Plastic pollution in human reproduction: should we worry?
Researchers reviewed evidence that micro- and nanoplastics can cross the placenta, enter amniotic fluid, and accumulate in reproductive tissues in both men and women. Animal and cell studies suggest these particles may reduce egg and sperm quality and harm fetal development, though most experiments use higher doses than people realistically encounter.
Implications of environmental toxicants on ovarian follicles: how it can adversely affect the female fertility?
This review examines how environmental toxicants, including endocrine disrupting chemicals, heavy metals, agrochemicals, and chemicals used in plastic and cosmetic industries, can adversely affect female fertility. Researchers found that these substances can interfere with follicle development and lead to conditions like polycystic ovary syndrome, premature ovarian insufficiency, and meiotic defects. The study highlights the difficulty of isolating individual risk factors since multiple toxicants often share common pathways of reproductive harm.
Reproductive toxicity and related mechanisms of micro(nano)plastics in terrestrial mammals: Review of current evidence.
This review of terrestrial mammal studies found that micro- and nanoplastics induce reproductive toxicity through oxidative stress, inflammation, endocrine disruption, and DNA damage, affecting both male and female fertility. In males, effects include blood-testis barrier disruption and impaired spermatogenesis, while females show compromised oocyte maturation, ovarian fibrosis, and diminished ovarian reserve, with particles also capable of crossing the maternal-fetal interface.
Toxicity of microplastics and nanoplastics: invisible killers of female fertility and offspring health
This review summarizes research on how microplastics and nanoplastics affect female fertility across multiple species, from reproductive failure to developmental problems in offspring. The tiny particles can infiltrate the body through food, air, and skin, accumulating in reproductive tissues where they disrupt hormones and damage eggs. While animal studies cannot be directly applied to humans, the consistent findings across species raise serious concerns about the potential impact of microplastic exposure on women's reproductive health.