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Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Human Health Effects Nanoplastics Policy & Risk Reproductive & Development Sign in to save

Microplastics and endocrine disruption: Emerging risks for human fertility

Journal of Biomedical Sciences 2025
Subasri Krishnarajan Anbuchelvan, Hashka Udayakumaran, Ang Yu Xin, Yoshita Loshni, Faria Rashid

Summary

This short communication reviewed emerging evidence that microplastics and nanoplastics disrupt endocrine function and reproductive health, highlighting effects on hormonal regulation, gametogenesis, and fertility outcomes. The authors called for more epidemiological studies to establish links between human microplastic exposure and fertility decline.

Background: Microplastics (MPs) and nanoplastics (NPs) are pervasive environmental contaminants that are increasingly recognised for their potential role in endocrine disruption and reproductive toxicity. These particles, ubiquitous in food, water, and air, harbour endocrine-disrupting chemicals (EDCs) and have demonstrated effects on hormonal regulation, gametogenesis, and fertility outcomes in both experimental and observational studies. This short communication highlights current knowledge on the association between microplastic exposure, endocrine disruption, and fertility issues, drawing on recent evidence.

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