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Microplastics and endocrine disruption: Emerging risks for human fertility
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This short communication reviewed emerging evidence that microplastics and nanoplastics disrupt endocrine function and reproductive health, highlighting effects on hormonal regulation, gametogenesis, and fertility outcomes. The authors called for more epidemiological studies to establish links between human microplastic exposure and fertility decline.
Background: Microplastics (MPs) and nanoplastics (NPs) are pervasive environmental contaminants that are increasingly recognised for their potential role in endocrine disruption and reproductive toxicity. These particles, ubiquitous in food, water, and air, harbour endocrine-disrupting chemicals (EDCs) and have demonstrated effects on hormonal regulation, gametogenesis, and fertility outcomes in both experimental and observational studies. This short communication highlights current knowledge on the association between microplastic exposure, endocrine disruption, and fertility issues, drawing on recent evidence.
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Microplastics and Fertility
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This paper reviews the growing body of evidence linking microplastic exposure to impaired human fertility, covering how microplastics and associated chemical additives can disrupt reproductive hormones and damage sperm and egg quality. It highlights the need for further research to establish dose-response relationships.
Adverse effects of microplastics and nanoplastics on the reproductive system: A comprehensive review of fertility and potential harmful interactions
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This review summarizes how microplastics and nanoplastics can harm both male and female reproductive systems by disrupting hormone signaling, damaging sperm and egg cells, and causing inflammation in reproductive tissues. Smaller nanoplastics are especially concerning because they can cross biological barriers more easily and reach the testes and ovaries. With global infertility rates rising, the authors highlight environmental plastic exposure as a factor that deserves more research attention.
Microplastics and Nanoplastics and Their Effects on Reproductive Health: Potential Risks and Mechanisms
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This review summarizes existing animal and cell studies on how tiny plastic particles (microplastics and nanoplastics) may harm fertility, damaging eggs, sperm, and embryo development by triggering cell stress and hormone disruption. While the exact risk to humans isn't confirmed yet, the findings highlight why reducing plastic exposure may matter for reproductive health.
Threats of nano/microplastics to reproduction and offspring: Potential mechanisms and perspectives
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This review summarized the evidence on how nano- and microplastics threaten reproduction and offspring health across multiple species, including fish, invertebrates, and mammals. The authors outlined potential mechanisms by which these plastic particles disrupt endocrine function, gonadal development, and embryonic development.
Toxicological effects of micro/nano-plastics on human reproductive health: A review
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This review summarizes research on how micro- and nanoplastics affect human reproductive health in both men and women. Evidence from animal and lab studies shows that these particles can accumulate in reproductive organs, disrupt hormones, damage eggs and sperm, and cause inflammation and oxidative stress. While human studies are still limited, the growing body of evidence suggests that microplastic exposure is a potential threat to fertility that warrants further investigation.
Research digests by email
When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.