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61,005 resultsShowing papers similar to Effect of chronic deltamethrin exposure on brain transcriptome and metabolome of juvenile crucian carp
ClearEvaluation of Detoxification‐Related Gene Expression, Oxidative Stress Biomarkers, and Blood Biochemical Parameters in Common Carp ( Cyprinus carpio ) Co‐Exposed to Polyethylene Microplastics and Deltamethrin
Researchers investigated whether polyethylene microplastics worsen the toxic effects of the insecticide deltamethrin in juvenile common carp over a 30-day exposure. The study found that co-exposure to microplastics and deltamethrin affected detoxification-related gene expression, oxidative stress biomarkers, and blood biochemistry, suggesting that microplastics can modify the bioavailability and toxicity of co-occurring pesticides in fish.
Conventional Anthelmintic Concentration of Deltamethrin Immersion Disorder in the Gill Immune Responses of Crucian Carp
Researchers investigated the effects of deltamethrin, a commonly used antiparasitic agent for fish, on the gill immune responses of crucian carp. The study found that even at conventional treatment concentrations, deltamethrin exposure caused significant gill tissue damage including hyperplasia, increased cell death, and disrupted immune-related gene expression over a 28-day period.
Exposure to Acute Concentration of Malathion Induced Behavioral, Hematological, and Biochemical Toxicities in the Brain of Labeo rohita
Researchers exposed Labeo rohita fish to acute concentrations of the pesticide malathion and measured toxic effects on blood chemistry and brain biochemistry. While this study focuses on pesticide toxicity rather than microplastics directly, it demonstrates how chemical pollutants found alongside microplastics in waterways can harm aquatic organisms. The findings showed significant disruption of brain enzymes and blood parameters, highlighting the vulnerability of commercially important fish to agricultural runoff.
Malathion-induced Biochemical and Molecular Changes in the Brain of Danio rerio as Biomarkers of Oxidative Stress Damage
Not relevant to microplastics — this study examines how the pesticide malathion causes oxidative stress and neurological damage in zebrafish brains, using antioxidant enzyme activity and gene expression as biomarkers.
Transcriptomics-based analysis of neurotoxic and reproductive effects in turbot (Scophthalmus maximus) after exposure to tris (2-chloroethyl) phosphate (TCEP)
This study used gene expression analysis to reveal that the flame retardant TCEP causes endocrine-disrupting effects in turbot fish, affecting both neurological and reproductive pathways. The findings identified specific biomarkers that could serve as early warning signs for monitoring the health impacts of this chemical pollutant on aquaculture species.
Effect of chlorpyrifos on freshwater microbial community and metabolic capacity of zebrafish
Researchers exposed zebrafish and their surrounding water to chlorpyrifos, a widely used pesticide, and found it disrupted the diversity of aquatic microbes, increased dangerous antibiotic-resistant bacteria, and altered the gut metabolism of fish — raising concerns about the ecological and food-safety risks of pesticide runoff into waterways.
Interactive Effects of BDE-153 and itsMetabolite 2,4-DBP on Biochemical Statusin Crucian Carp (Carassius auratus)
This study examined how polybrominated diphenyl ethers (PBDEs) — flame retardants found in many plastics — and their metabolites affect biochemical markers in organisms. The findings suggest that even metabolized breakdown products of plastic-associated flame retardants can disrupt normal biological functions.
Suborganismal responses of the aquatic midge Chironomus riparius to polyethylene microplastics
Researchers exposed Chironomus riparius larvae to polyethylene microplastics and used transcriptomics and metabolomics to characterize suborganismal responses, finding disruption of oxidative stress pathways, energy metabolism, and cuticle synthesis — effects not captured by standard life-history endpoints alone.
The effects of exposure to microplastics on grass carp (Ctenopharyngodon idella) at the physiological, biochemical, and transcriptomic levels
Researchers exposed grass carp to microplastics at two concentrations for 21 days and observed liver damage, inhibited growth, and increased oxidative stress. Transcriptome analysis revealed over 1,500 differentially expressed genes related to immune response, metabolism, and cellular stress pathways. The study suggests that microplastic exposure can trigger broad physiological and molecular disruptions in freshwater fish.
Lipid Metabolism and Oxidative Stress Altered in Crucian Carp (Carassius auratus) Following Exposure to Microplastics Under Laboratory and Field Conditions
Researchers used high-throughput sequencing to assess the impact of microplastics on crucian carp under both field and laboratory conditions. After four weeks of in-situ exposure, intestinal microplastic levels slightly increased, and transcriptome analysis revealed over 3,000 differentially expressed genes in the liver, with notable enrichment in pathways related to lipid metabolism and oxidative stress.
Combined transcriptome and metabolite profiling analyses provide insights into the chronic toxicity of carbaryl and acetamiprid to Apis mellifera larvae
Researchers exposed honeybee larvae to low, non-lethal doses of two common insecticides — carbaryl and acetamiprid — and found distinct disruptions in gene activity and metabolism, including effects on antioxidant defenses and amino acid processing. These findings reveal that even "safe" pesticide levels can cause subtle but meaningful biological harm to developing bees, which are essential for pollinating crops.
Metabolomic responses in freshwater benthic invertebrate, Chironomus tepperi, exposed to polyethylene microplastics: A two-generational investigation
Researchers examined metabolomic changes in the freshwater midge Chironomus tepperi exposed to polyethylene microplastics across two generations, finding that environmentally relevant concentrations altered metabolite profiles and negatively affected survival and emergence.
Combined transcriptome and metabolite profiling analyses provide insights into the chronic toxicity of carbaryl and acetamiprid to Apis mellifera larvae
Researchers exposed honeybee larvae in vitro to no-observed-adverse-effect concentrations of the insecticides carbaryl and acetamiprid and used combined transcriptome and metabolite profiling to reveal that carbaryl disrupted oxidative stress responses and amino acid metabolism, while acetamiprid altered different metabolic pathways.
Transcriptome analysis provides insights into copper toxicology in piebald naked carp (Gymnocypris eckloni)
Researchers exposed piebald naked carp to copper — a common water pollutant — and found it significantly disrupted gene activity in the gills and liver, particularly genes involved in building proteins, suggesting that fish respond to metal-induced stress by broadly slowing down protein production as a protective mechanism.
Pyriproxyfen Contamination in Daphnia magna: Identifying Early Warning Biomarkers
Researchers tested the effects of the insecticide pyriproxyfen on water fleas, a common freshwater organism used as an environmental health indicator. They found that even at low concentrations similar to those detected in European rivers, the insecticide disrupted key enzymes and gene expression patterns. The study suggests these biochemical changes could serve as early warning signs of broader ecological disruption in freshwater ecosystems.
Combined effects of polystyrene micro-/nano-plastics and imidacloprid on Gut–Brain axis and neurotoxicity in juvenile Carassius auratus
Researchers exposed juvenile crucian carp to polystyrene micro- and nanoplastics combined with the pesticide imidacloprid and found distinct size-dependent toxicity patterns. Nanoplastics primarily targeted the brain, causing blood-brain barrier breakdown and neurotoxic effects linked to behavioral changes, while microplastics caused more severe intestinal damage, with gut microbiome analysis implicating the microbiota-gut-brain axis as a pathway for systemic toxicity.
Regulation of Gene Expression in Fish
This paper is not relevant to microplastics research — it is a broad review of how environmental pollutants regulate gene expression in fish, covering heavy metals, pesticides, and endocrine disruptors.
Toxic effects of polyethylene microplastics on transcriptional changes, biochemical response, and oxidative stress in common carp (Cyprinus carpio)
Researchers exposed common carp to varying concentrations of polyethylene microplastics and assessed biochemical, oxidative, and gene expression changes. The study found that microplastic exposure caused significant oxidative stress, altered liver enzyme activity, and modified the expression of stress-related genes in a dose-dependent manner.
Histopathological Alteration in Detoxifying Organs (Liver and Kidney) of Freshwater Fish Ctenopharyngodon idella Exposed to Lufenuron
Researchers exposed grass carp (Ctenopharyngodon idella) to the insecticide lufenuron at 0–4 µg/L for 33 days and assessed histopathological changes in liver and kidney. Liver tissues showed vacuolation, necrosis, and inflammatory infiltration while kidneys showed degenerative changes, with severity increasing with concentration and duration of exposure.
Nanoplastics impact the zebrafish (Danio rerio) transcriptome: Associated developmental and neurobehavioral consequences
Researchers exposed developing zebrafish larvae to polystyrene nanoplastics of two sizes and found dose-dependent accumulation in tissues along with swimming hyperactivity, despite no effects on mortality or hatching. Transcriptomic analysis revealed changes in gene expression associated with neurodegeneration and motor dysfunction at both high and low concentrations. The study suggests that nanoplastic exposure during early development can alter brain function and behavior in ways that may reduce organismal fitness.
Combined hepatotoxicity of imidacloprid and microplastics in adult zebrafish: Endpoints at gene transcription
Researchers investigated the combined liver toxicity of the pesticide imidacloprid and polystyrene microplastics in adult zebrafish over 21 days. The combination caused greater changes in gene expression related to fat and sugar metabolism and inflammatory responses than either contaminant alone. The study suggests that even low concentrations of microplastics and pesticides together may produce more severe hepatotoxic effects than individual exposures.
Effect of Polystyrene Microplastic Exposure on Individual, Tissue, and Gene Expression in Juvenile Crucian Carp (Carassius auratus)
Juvenile crucian carp were exposed to polystyrene microplastics at different concentrations, and researchers found that the particles accumulated mainly in the intestines and gills. The study suggests that microplastic exposure caused tissue damage to multiple organs and altered gene expression, with higher concentrations generally leading to more severe effects.
Transcriptome sequencing and metabolite analysis reveal the toxic effects of nanoplastics on tilapia after exposure to polystyrene
Researchers exposed larval tilapia to polystyrene nanoplastics and then analyzed changes in gene expression and metabolic profiles after a recovery period. They found that nanoplastic exposure disrupted immune-related pathways, energy metabolism, and lipid processing in the fish, with some effects persisting even after exposure ended. The study suggests that nanoplastics can cause lasting metabolic and immune disruptions in freshwater fish.
Evaluation of behavioral and neurochemical changes induced by carbofuran in zebrafish ( Danio rerio )
Researchers evaluated behavioral and neurochemical changes in zebrafish exposed to carbofuran, a carbamate pesticide widely used in agriculture and detected as an environmental contaminant in food and water. The study found that carbofuran exposure induced anxiety-like behavior and disrupted neurotransmitter systems in zebrafish at environmentally relevant concentrations.