We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Papers
61,005 resultsShowing papers similar to The probiotic SLAB51 as agent to counteract BPA toxicity on zebrafish gut microbiota -liver-brain axis
ClearInvestigating the modulation of the endocannabinoid system by probiotic Lactiplantibacillus plantarum IMC513 in a zebrafish model of di-n-hexyl phthalate exposure
Researchers found that a probiotic strain (Lactiplantibacillus plantarum IMC513) protected zebrafish from neurological disruption caused by di-n-hexyl phthalate, a plasticizer chemical used in food packaging, by restoring normal gene expression in the brain's endocannabinoid signaling system. This suggests probiotics may help counteract the brain and gut effects of phthalate exposure from plastic products.
Lactiplantibacillus plantarum P101 Alleviates Liver Toxicity of Combined Microplastics and Di-(2-Ethylhexyl) Phthalate via Regulating Gut Microbiota
Researchers found that the probiotic Lactiplantibacillus plantarum P101 reduced liver damage caused by combined exposure to microplastics and the plasticizer DEHP in mice. The probiotic reversed oxidative stress and inflammation in the liver and intestines while reshaping the gut microbiota. The study suggests that probiotic supplementation may offer a promising strategy for mitigating the toxic effects of co-exposure to microplastics and plastic-associated chemicals.
Gut microbiota and liver metabolomics reveal the potential mechanism of Lactobacillus rhamnosus GG modulating the liver toxicity caused by polystyrene microplastics in mice
Researchers found that the probiotic Lactobacillus rhamnosus GG helped protect mice from liver damage caused by polystyrene microplastic exposure. The probiotic worked by restoring healthy gut bacteria and normalizing liver metabolic pathways disrupted by the microplastics. The study suggests that supporting gut health through beneficial bacteria may help mitigate some of the toxic effects microplastics have on the liver.
Damage of polyethylene microplastics on the intestine multilayer barrier, blood cell immune function and the repair effect of Leuconostoc mesenteroides DH in the large-scale loach (Paramisgurnus dabryanus)
Researchers found that polyethylene microplastics damage the intestinal lining of loach fish, allowing plastic particles to break through the gut barrier and enter the bloodstream, where they caused blood cell death. Adding a probiotic bacterium (Leuconostoc mesenteroides) to the fish's diet significantly repaired the intestinal damage and improved immune function. This suggests that probiotics may help counteract some of the gut damage caused by microplastic exposure.
Lactic acid bacteria reduce polystyrene micro- and nanoplastics-induced toxicity through their bio-binding capacity and gut environment repair ability
Researchers found that lactic acid bacteria, the kind used in yogurt and fermented foods, can reduce the toxic effects of polystyrene micro and nanoplastics in mice. The bacteria worked by physically binding to the plastic particles and by repairing damage to the gut lining and restoring healthy gut bacteria populations. This suggests that probiotics could be a practical way to help protect the digestive system from the harmful effects of microplastic exposure through food and water.
Probiotics as Modulators of Microplastic-induced Toxicity: A Systematic Review
This systematic review found that probiotics can reduce microplastic-induced toxicity in animal models by restoring gut microbiota balance, reducing oxidative stress, and modulating inflammatory responses. The findings suggest that probiotic supplementation may help mitigate the harmful effects of unavoidable microplastic exposure, though human clinical trials are still needed.
Polystyrene nanoplastics sequester the toxicity mitigating potential of probiotics by altering gut microbiota in grass carp (Ctenopharyngodon idella)
Researchers tested whether probiotic pretreatment could protect grass carp from the toxic effects of polystyrene nanoplastics on gut health. While probiotics initially boosted immune responses and reduced intestinal damage, the protective effect was not strong enough to fully counteract nanoplastic toxicity over time. The study suggests that nanoplastics can undermine the gut health benefits of probiotics by disrupting the balance of gut bacteria.
Lactobacillus plantarum reduces polystyrene microplastic induced toxicity via multiple pathways: A potentially effective and safe dietary strategy to counteract microplastic harm
Researchers found that Lactobacillus plantarum, a probiotic bacterium commonly found in fermented foods, can reduce the harmful effects of polystyrene microplastics in mice through multiple pathways. The bacteria worked by binding directly to plastic particles to help remove them from the body, reducing oxidative damage, repairing the intestinal barrier, and regulating bile acid metabolism. This suggests that certain probiotics could be a safe dietary strategy to help counteract some of the negative health effects of microplastic exposure.
Oxidized/unmodified-polyethylene microplastics neurotoxicity in mice: Perspective from microbiota-gut-brain axis
Mice exposed to both regular and environmentally weathered polyethylene microplastics developed brain and gut damage, including behavioral changes, weakened gut and blood-brain barriers, and inflammation -- with weathered microplastics causing even more harm. Importantly, treatment with a probiotic (Lactobacillus) and a prebiotic partially reversed these effects, suggesting that gut-friendly supplements might help protect against microplastic-related brain and intestinal damage.
Probiotics ameliorate polyethylene microplastics-induced liver injury by inhibition of oxidative stress in Nile tilapia (Oreochromis niloticus)
Researchers investigated whether probiotics could protect Nile tilapia from liver damage caused by polystyrene microplastics. The study found that fish pre-fed with probiotics showed significantly reduced oxidative stress markers in the liver compared to those exposed to microplastics alone, suggesting that probiotics may help mitigate microplastic-induced hepatic oxidative damage in fish.
A probiotic for preventing microplastic toxicity: Clostridium dalinum mitigates microplastic-induced damage via microbiota-metabolism-barrier interactions
Using metagenomics and metabolomics, this study found that the probiotic bacterium Clostridium dalinum reduced microplastic-induced gut damage in mice by modulating gut microbiota composition, metabolic pathways, and intestinal barrier integrity.
Lactiplantibacillus plantarum ZP-6 mitigates polystyrene nanoplastics-induced liver damage in colitis mice via the gut-liver axis
The probiotic strain Lactiplantibacillus plantarum ZP-6 mitigated polystyrene nanoplastic-induced liver injury in an animal model through multiple mechanisms including toxin binding, barrier enhancement, and anti-inflammatory activity, suggesting probiotics as a potential strategy for reducing nanoplastic health impacts.
Influence of Bisphenol a and Probiotic-containing Feedcarassius Gibelio Bloch Indicates Separately
This study examined how bisphenol A (BPA), a plastic monomer and hormone-disrupting chemical, affects the behavior, physiology, and health of a freshwater fish when administered in feed, and whether probiotic supplements could reduce these harmful effects. BPA is a widespread aquatic pollutant that enters waterways from plastic manufacturing and consumer product leaching.
Probiotics improve polystyrene microplastics-induced male reproductive toxicity in mice by alleviating inflammatory response
Researchers found that giving mice probiotics (beneficial bacteria including Lactobacillus and Bifidobacterium) helped protect against reproductive damage caused by polystyrene microplastics. The microplastics disrupted gut bacteria and triggered inflammation that traveled to the testes via the gut-testis connection, reducing sperm quality and testosterone levels. Probiotic treatment restored healthy gut bacteria and reduced the inflammatory response, suggesting that maintaining gut health could help counteract some reproductive harm from microplastic exposure.
Probiotics an emerging therapeutic approach towards gut-brain-axis oriented chronic health issues induced by microplastics: A comprehensive review
This review examines how microplastics disrupt the gut-brain axis, the communication system between the digestive system and the brain, leading to chronic health problems like inflammation and neurological issues. The authors highlight probiotics as a promising treatment approach, since beneficial bacteria can help repair gut damage caused by microplastic exposure. The findings suggest that supporting gut health through probiotics may help counteract some of the harmful effects of microplastics on both digestion and brain function.
Impacts of polystyrene nanoplastics on zebrafish gut microbiota and mechanistic insights
Zebrafish exposed to polystyrene nanoplastics showed significant changes in their gut bacteria, with beneficial species like Bifidobacterium declining and potentially harmful bacteria increasing. The nanoplastics physically entered intestinal tissues, causing visible damage to gut cells. This study is relevant to human health because our gut microbiome plays a key role in immunity and digestion, and similar disruption from nanoplastic exposure could contribute to digestive and immune problems.
Could probiotics protect against human toxicity caused by polystyrene nanoplastics and microplastics?
This review examines whether probiotics could help protect against the harmful effects of polystyrene nanoplastics and microplastics in the body. Researchers found evidence that probiotic bacteria may counteract plastic-induced gut imbalances, reduce inflammation, and support intestinal barrier function. The study suggests that probiotics represent a promising area of research for mitigating some of the biological effects of microplastic exposure, though more human studies are needed.
Probiotics as a therapeutic approach to alleviate reproductive harm from polystyrene microplastics in male rats
Researchers tested whether probiotic supplementation could protect against reproductive toxicity caused by polystyrene microplastic exposure in male rats, finding that PS-MP caused dose-dependent testicular damage and disrupted kisspeptin signaling in the hypothalamus. Probiotics partially reversed these effects, suggesting a gut-testis axis through which microbiome modulation may mitigate reproductive harm.
The Effects of Probiotics on the Recovery of Growth, Digestive, Antioxidant, Immune Functions, and Gut Microbiota of Chinese Hooksnout Carp (Opsariichthys bidens) Under Microplastic Stress
Researchers exposed juvenile Chinese hooksnout carp to polystyrene microplastics for seven days, then administered Bacillus coagulans probiotics at three doses for 56 days and found that medium and high probiotic doses significantly improved growth, digestive enzyme activity, antioxidant function, and gut microbiota recovery.
The microplastic-crisis: Role of bacteria in fighting microplastic-effects in the digestive system
This review examines how microplastics affect the human digestive system and explores whether certain bacteria could help counteract the damage. Microplastics disrupt the gut by altering microbial communities, interfering with digestive enzymes, and damaging the protective mucus lining. The authors highlight the potential for probiotic bacteria to bind to microplastics, reduce inflammation, and help repair the gut environment, offering a possible protective strategy against microplastic-related digestive harm.
Small fish, big discoveries: zebrafish shed light on microbial biomarkers for neuro-immune-cardiovascular health
This review highlighted how zebrafish serve as a powerful model for studying gut microbiome links to cardiovascular, neurological, and immune health, identifying microbial biomarkers that could inform future research on environmental stressor impacts including microplastic exposure.
Multi-Species Probiotics as Sustainable Strategy to Alleviate Polyamide Microplastic-Induced Stress in Nile Tilapia
Researchers tested whether multi-species probiotics could counteract the toxic effects of polyamide microplastics in Nile tilapia over a six-week experiment. The study found that probiotic supplementation alleviated microplastic-induced stress by improving growth performance, immune response, and physiological health markers, suggesting that probiotics may be a sustainable strategy for protecting farmed fish from microplastic contamination.
Polystyrene Nanoplastics Toxicity to Zebrafish: Dysregulation of the Brain–Intestine–Microbiota Axis
This study found that polystyrene nanoplastics disrupted the brain-gut connection in zebrafish at environmentally realistic concentrations, affecting growth, gut health, and brain chemistry. The nanoplastics altered neurotransmitter levels, particularly reducing a dopamine-related compound, and changed the balance of gut bacteria in ways that correlated with brain changes. These findings suggest a pathway by which nanoplastics in food and water could affect both digestive and brain health through the gut-brain axis.
Engineered Probiotics Mitigate Gut Barrier Dysfunction Induced by Nanoplastics
Researchers engineered a probiotic-based system using modified E. coli Nissle 1917 bacteria to counteract gut barrier damage caused by nanoplastics derived from PET food packaging. The engineered probiotic was designed to produce an anti-inflammatory protein and was coated for better survival in the digestive tract, where it reduced inflammation, restored gut barrier function, and rebalanced gut bacteria in animal models. The study suggests that engineered probiotics could be a promising approach for protecting the gut from nanoplastic-related damage.