We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Papers
61,005 resultsShowing papers similar to Associations between concentrations of microplastics in follicular fluid and the risk of diminished ovarian reserve
ClearSize- and hydrophobicity-dependent accumulation of microplastics in follicular fluid is linked to impaired ovarian reserve in women undergoing medically assisted reproduction
Researchers measured microplastic concentrations in follicular fluid and blood from women undergoing fertility treatment and found that nearly all samples contained microplastics. Higher microplastic concentrations in follicular fluid were significantly associated with reduced oocyte yield and lower odds of pregnancy, with evidence suggesting that certain hydrophobic polymers selectively accumulate in the ovary.
Microplastics and nanoplastics in follicular fluid are associated with diminished ovarian reserve: clinical and molecular insights
Researchers found that microplastics and nanoplastics present in follicular fluid are associated with diminished ovarian reserve in women. The study provides evidence suggesting that exposure to these particles may harm female ovarian function. The findings point to the environment-gut-ovarian axis as a potential pathway through which micro- and nanoplastic exposure could contribute to reproductive health concerns.
Characterization of microplastics in human follicular fluid and assessment of their potential impact on mouse oocyte maturation in vitro
Scientists found microplastics in human follicular fluid, the liquid surrounding eggs in the ovaries, after analyzing samples from 19 women. When they tested how these particles affect egg development in mice, they found that certain types of microplastics reduced the ability of eggs to mature properly, raising concerns about potential effects on fertility.
Polyethylene microplastic exposure adversely affects oocyte quality in human and mouse
Researchers found polyethylene microplastics (the most common plastic type) in the fluid surrounding eggs in 86% of women undergoing fertility treatment, and higher levels correlated with lower fertilization rates. Mouse experiments confirmed that polyethylene exposure reduced the number and quality of eggs while increasing inflammation, suggesting microplastics may be a contributing factor to fertility challenges.
Polyethylene and Polyvinyl Chloride Nanoplastics in Human Follicular Fluid and Seminal Plasma: Impact on Fertilization and Sperm Quality
Researchers detected polyethylene and PVC nanoplastics in both the follicular fluid and seminal plasma of 51 couples undergoing IVF treatment. Higher levels of PVC nanoplastics in seminal plasma were associated with lower sperm concentration and fewer high-quality embryos, while nanoplastics in follicular fluid showed no significant effect on fertilization rates. This is among the first studies to directly measure nanoplastics in human reproductive fluids and link them to reduced fertility outcomes.
First evidence of microplastics in human ovarian follicular fluid: an emerging threat to female fertility
In the first study of its kind, researchers detected microplastics in the ovarian follicular fluid of 14 out of 18 women undergoing fertility treatment, with an average of about 2,191 particles per milliliter. A significant correlation was found between microplastic concentration and FSH hormone levels, suggesting a possible link to reproductive function. This groundbreaking finding provides direct evidence that microplastics can reach human reproductive organs and may pose a threat to female fertility.
First evidence of microplastics in human ovarian follicular fluid: An emerging threat to female fertility
For the first time, researchers detected microplastic particles in the fluid surrounding eggs in human ovaries. Tiny plastic particles were found in 14 out of 18 women undergoing fertility treatment, and higher microplastic levels correlated with elevated follicle-stimulating hormone, a key reproductive hormone. While no direct link to fertility outcomes was confirmed in this small study, the findings raise concerns about microplastic exposure and female reproductive health.
Microplastics are present in women’s and cows’ follicular fluid and polystyrene microplastics compromise bovine oocyte function in vitro
Researchers detected microplastics in both women's and cows' follicular fluid for the first time, and showed that polystyrene microplastics impair bovine oocyte function in vitro, raising concern that environmental microplastic exposure may be contributing to declining reproductive health.
Polyethylene andPolyvinyl Chloride Nanoplastics inHuman Follicular Fluid and Seminal Plasma: Impact on Fertilizationand Sperm Quality
Researchers used pyrolysis GC/MS to detect polyethylene (PE) and polyvinyl chloride (PVC) nanoplastics in follicular fluid and seminal plasma from 51 IVF couples. Both polymers were present in both reproductive fluids, and while associations with fertilization outcomes were not statistically significant, the detection of nanoplastics in human reproductive fluids represents a novel concerning finding.
Microplastics are present in women’s and cows’ follicular fluid and polystyrene microplastics compromise bovine oocyte function in vitro
Researchers detected microplastics in follicular fluid from both women and cows and showed that polystyrene microplastics disrupt oocyte development, providing the first evidence that microplastics can penetrate reproductive barriers and potentially contribute to the global decline in fertility.
Microplastics are present in women’s and cows’ follicular fluid and polystyrene microplastics compromise bovine oocyte function in vitro
Researchers detected microplastics in the follicular fluid of both women and cows, marking one of the first studies to find these particles in reproductive tissues. In laboratory tests, polystyrene microplastics impaired bovine egg cell function at concentrations comparable to what was found in the follicular fluid. The findings raise questions about whether microplastic exposure could be a contributing factor in the widespread declines in reproductive health observed in recent decades.
Plastic Particles and Female Fertility: Pathways, Toxicity, and Analytical Challenges
This review examines the pathways, toxicity mechanisms, and analytical challenges associated with microplastic and nanoplastic impacts on female fertility. Evidence from animal studies indicates that these particles can accumulate in ovaries and placental tissue, inducing oxidative stress, inflammation, and granulosa cell death that diminishes ovarian reserve. The study notes that microplastics have been confirmed in human placentas and umbilical cord blood, and may disrupt the hormonal axis governing reproduction.
Exposição De Microplásticos E Nanoplásticos Ao Tecido Ovariano: Uma Revisão Integrativa
This integrative review (in Portuguese) examines published evidence on the effects of micro- and nanoplastic exposure on female ovarian tissue morphology, finding disrupted folliculogenesis, oxidative stress, and hormonal interference reported across animal model studies.
Impact of microplastics on female reproductive health: insights from animal and human experimental studies: a systematic review
This systematic review of 15 experimental studies found that microplastic exposure significantly impairs ovarian function, decreases fertility rates, and disrupts hormone levels in female subjects. Several studies also reported negative effects on embryo development and offspring health, though study quality varied and more rigorous research is needed to confirm mechanisms.
Exposição De Microplásticos E Nanoplásticos Ao Tecido Ovariano: Uma Revisão Integrativa
This integrative review examines the impact of micro- and nanoplastics on female ovarian tissue, synthesizing animal model studies showing damage to follicular structures, increased oxidative stress, and disrupted reproductive hormone signaling.
P-762 Discovery and quantification of microplastics in human cumulus granulosa cells
Researchers detected microplastics for the first time in human cumulus granulosa cells and follicular fluid, with polyethylene and polypropylene being the most common types found. The study examined 16 women undergoing assisted reproduction and found that higher microplastic concentrations in these reproductive cells were associated with poorer outcomes in fertility treatments. The findings suggest that microplastic contamination of the female reproductive system may warrant further investigation as a potential factor in reproductive health.
The effects of exposure to microplastics on female reproductive health and pregnancy outcomes: A systematic review and meta-analysis
This meta-analysis pools data from multiple studies to assess how microplastic exposure affects female reproductive health and pregnancy outcomes. The findings suggest that microplastic accumulation may be linked to adverse effects on fertility and pregnancy, highlighting an important and underexplored area of concern for women's health.
A review of the impact of micro‐ and nanoplastics on female reproduction: What we know and gaps in knowledge
This review examines what is known about how micro- and nanoplastics affect female reproductive health. Animal studies show these particles accumulate in ovarian tissue, disrupt hormones, and cause oxidative stress, leading to hormonal imbalances and ovarian damage, though research in humans is still limited.
Microplastics in ovarian function and ozone-based mitigation strategies: Emerging evidence and translational implications
This review synthesized emerging evidence that microplastics accumulate in human follicular fluid, oocytes, placenta, and semen, causing oxidative stress, mitochondrial dysfunction, and meiotic disruption in reproductive cells, and discussed ozone-based strategies as potential mitigation approaches.
Detection and quantification of microplastics in endometrial polyps and their role in polyp formation
Researchers detected and compared microplastic levels between normal uterine lining tissue and endometrial polyps, finding significantly higher concentrations of polyethylene, polystyrene, and PVC in the polyp tissue. They also discovered that polystyrene microplastics can promote the growth and migration of uterine lining cells through a specific cellular signaling pathway, which may contribute to polyp formation. This is the first study to link microplastic accumulation in reproductive tissue to a common gynecological condition that can affect fertility.
Concerning influences of micro/nano plastics on female reproductive health: focusing on cellular and molecular pathways from animal models to human studies
This review summarizes research showing that micro- and nanoplastics can harm the female reproductive system in multiple ways, from reducing ovarian reserves and disrupting hormone balance to accumulating in the placenta and breast milk. Animal studies show these particles trigger oxidative stress and inflammation in reproductive tissues, and human studies have confirmed their presence in placental tissue and infant feces, raising concerns about effects on fertility and fetal development.
Association Between Microplastic Exposure and Cognitive Function Decline
Researchers detected PET and polypropylene microplastics in blood, urine, and feces of study participants and found a significant association between higher microplastic concentrations in biological fluids and greater cognitive function decline, particularly among those with the highest exposure levels.
Implication of nano and microplastics in reproduction: understanding oocyte vulnerability
This review examined how nano- and microplastics (NMPs) compromise oocyte quality and female reproductive function, finding that NMPs trigger oxidative stress, disrupt meiotic spindle assembly, impair mitochondrial function, and cause DNA damage in eggs. The findings identified the oocyte as particularly vulnerable to NMP exposure, with implications for fertility and reproductive health.
Exposure to microplastics leads to a defective ovarian function and change in cytoskeleton protein expression in rat
Researchers exposed female rats to polystyrene microplastics over multiple reproductive cycles and found, for the first time, that the particles accumulated in different parts of the ovarian tissue. The microplastics reduced ovarian weight, disrupted the normal development of egg follicles, altered the reproductive cycle, and lowered estrogen levels. The study suggests these effects are driven by oxidative stress and changes in key structural proteins within the ovary.