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Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Gut & Microbiome Human Health Effects Nanoplastics Reproductive & Development Sign in to save

Microplastics and nanoplastics in follicular fluid are associated with diminished ovarian reserve: clinical and molecular insights

Journal of Advanced Research 2026
Manfei Si, G. F. Xu, Chuyu Yun, Yongyan Chen, Hongyu Niu, Yi Qu, Mengyu Liu, Yuqian Wang, Lixuan Huang, Xiaoyu Long, Wei Wang, Wei Wang, Rui Yang, Rui Liu, Rui Liu, Y J Pang, Xiumei Zhen, Rong Li, Tian Tian, Xinyu Qi, Jie Qiao

Summary

Researchers found that microplastics and nanoplastics present in follicular fluid are associated with diminished ovarian reserve in women. The study provides evidence suggesting that exposure to these particles may harm female ovarian function. The findings point to the environment-gut-ovarian axis as a potential pathway through which micro- and nanoplastic exposure could contribute to reproductive health concerns.

Body Systems

These findings elucidate how exposure to MNPs may harm female ovarian function and provide potential new strategies for ameliorating reproductive disorders through the environment‒gut‒ovarian axis.

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