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Association Between Microplastic Exposure and Cognitive Function Decline

Alzheimer s & Dementia 2025 Score: 48 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.

Pukovisa Prawiroharjo, Pukovisa Prawiroharjo, Pukovisa Prawiroharjo, Pukovisa Prawiroharjo, Anyelir Nielya Mutiara Putri, Anyelir Nielya Mutiara Putri, Anyelir Nielya Mutiara Putri, Anyelir Nielya Mutiara Putri, Noryanto Ikhromi, Noryanto Ikhromi, Noryanto Ikhromi, Elizabeth Divina, Elizabeth Divina, Elizabeth Divina, Rani Intan Permata, Elizabeth Divina, Rani Intan Permata, Anyelir Nielya Mutiara Putri, Noryanto Ikhromi, Rani Intan Permata, Talitha Najmillah Sabtiari, Rani Intan Permata, Talitha Najmillah Sabtiari, Alditya Fakhri, Elizabeth Divina, Alditya Fakhri, Alya Ayu Tazkia, Alya Ayu Tazkia, Viola Aprillia, Viola Aprillia, Dinda Nisrina, Dinda Nisrina

Summary

Researchers detected PET and polypropylene microplastics in blood, urine, and feces of study participants and found a significant association between higher microplastic concentrations in biological fluids and greater cognitive function decline, particularly among those with the highest exposure levels.

Polymers

PE PET PP

Polyethylene terephthalate (PET) and polypropylene (PP) microplastics were detected in respondents' blood, urine, and feces at varying concentrations. A significant association was observed between MP exposure levels and MP concentrations in biological fluids. Higher MP concentrations were linked to cognitive decline, particularly among respondents with the highest MP levels. Risk perception regarding MPs was higher among respondents with greater awareness and knowledge, while attitudes toward MPs correlated with plastic consumption patterns CONCLUSION: This study demonstrates a significant relationship between MP exposure and health impacts, particularly cognitive decline. These findings underscore the urgency of reducing plastic use, raising public awareness, and implementing policies for plastic waste management to mitigate health risks associated with MPs.

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