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Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Human Health Effects Sign in to save

Association Between Microplastic Exposure and Cognitive Function Decline

Alzheimer s & Dementia 2025
Pukovisa Prawiroharjo, Anyelir Nielya Mutiara Putri, Anyelir Nielya Mutiara Putri, Noryanto Ikhromi, Elizabeth Divina, Elizabeth Divina, Rani Intan Permata, Talitha Najmillah Sabtiari, Alditya Fakhri, Alya Ayu Tazkia, Viola Aprillia, Dinda Nisrina

Summary

Researchers detected PET and polypropylene microplastics in blood, urine, and feces of study participants and found a significant association between higher microplastic concentrations in biological fluids and greater cognitive function decline, particularly among those with the highest exposure levels.

Polymers
PE PET PP

Polyethylene terephthalate (PET) and polypropylene (PP) microplastics were detected in respondents' blood, urine, and feces at varying concentrations. A significant association was observed between MP exposure levels and MP concentrations in biological fluids. Higher MP concentrations were linked to cognitive decline, particularly among respondents with the highest MP levels. Risk perception regarding MPs was higher among respondents with greater awareness and knowledge, while attitudes toward MPs correlated with plastic consumption patterns CONCLUSION: This study demonstrates a significant relationship between MP exposure and health impacts, particularly cognitive decline. These findings underscore the urgency of reducing plastic use, raising public awareness, and implementing policies for plastic waste management to mitigate health risks associated with MPs.

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