Papers

20 results
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Article Tier 2

Exploring the impact of nano-Se and nano-clay feed supplements on interleukin genes, immunity and growth rate in European Sea Bass (Dicentrarchus labrax)

Researchers tested nano-selenium and nano-clay as feed supplements in European sea bass and found both activated immune genes and boosted expression of key inflammatory signals at various doses. These findings help identify effective concentration ranges for using nanoparticle supplements to support fish health in aquaculture.

2024 Scientific Reports 10 citations
Article Tier 2

Protective role of nano-selenium on Gymnocypris przewalskii under saline–alkaline stress: a comprehensive analysis of transcriptomics and metabolomics

Scientists studied a type of fish that lives in very salty, harsh water and found that tiny selenium particles helped protect the fish from stress and damage. The selenium particles worked by changing how the fish's genes and body chemistry responded to the difficult environment. While this study was done in fish, selenium is an important nutrient for humans too, and this research could help scientists better understand how selenium protects our bodies from environmental stress and damage.

2026 Fish Physiology and Biochemistry
Article Tier 2

Insights into the molecular response of Dioithona rigida to selenium nanoparticles: de novo transcriptome assembly and differential gene expression analysis

Researchers exposed a marine copepod species to selenium nanoparticles and used genetic analysis to understand the molecular-level effects. They found significant changes in genes related to DNA repair, oxidative stress response, and cell membrane function. The study matters because copepods are a key link in marine food chains, so contaminant effects on these tiny organisms can have ripple effects through the ecosystem and ultimately affect the seafood humans consume.

2024 Science and Technology of Advanced Materials 6 citations
Article Tier 2

Nano-selenium ameliorates microplastics-induced injury: Histology, antioxidant capacity, immunity and intestinal microbiota of grass carp (Ctenopharyngodon idella)

Researchers tested whether nano-selenium supplements could protect grass carp from damage caused by polystyrene microplastics. They found that nano-selenium reduced the tissue damage, oxidative stress, and immune suppression caused by microplastic exposure, and helped restore healthy gut bacteria. The study suggests that dietary nano-selenium may be a practical strategy for protecting farmed fish from the harmful effects of microplastic pollution in aquatic environments.

2024 Ecotoxicology and Environmental Safety 9 citations
Article Tier 2

Effect of Different Dietary Selenium Sources on Growth Performance, Antioxidant Capacity, Gut Microbiota, and Molecular Responses in Pacific White Shrimp Litopenaeus vannamei

Researchers investigated how different dietary selenium sources affect growth, antioxidant capacity, and gut microbiota in Pacific white shrimp, finding that selenium nanoparticles and selenium yeast provided superior antioxidant protection compared to inorganic selenium.

2022 Aquaculture Nutrition 29 citations
Article Tier 2

From Antioxidant Defenses to Transcriptomic Signatures: Concentration-Dependent Responses to Polystyrene Nanoplastics in Reef Fish

Researchers exposed clownfish to polystyrene nanoplastics at low and high concentrations for seven days and assessed toxic effects using biochemical and gene expression analyses. While standard antioxidant biomarkers showed limited changes, transcriptomic analysis revealed significant alterations in stress response and metabolic pathways at higher concentrations. The study suggests that conventional biomarkers may underestimate nanoplastic toxicity, and that molecular-level analysis is needed to capture the full scope of effects on reef fish.

2026 Microplastics
Article Tier 2

Toxicity assessment of the selenium nanoparticles in vitro ‎

A toxicity assessment of selenium nanoparticles evaluated cytotoxic effects, inflammatory responses, and oxidative stress in vitro, providing baseline data for regulatory safety evaluation of selenium-based nanomaterials. The study contributes to growing literature on nanoparticle hazard characterization.

2023 Journal Of Advanced Pharmacy Education And Research 4 citations
Article Tier 2

Nano Iron Versus Bulk Iron Forms as Functional Feed Additives: Growth, Body Indices, Hematological Assay, Plasma Metabolites, Immune, Anti-oxidative Ability, and Intestinal Morphometric Measurements of Nile tilapia, Oreochromis niloticus

Researchers compared the effects of feeding Nile tilapia fish diets supplemented with regular iron oxide versus nano-sized iron oxide particles. Fish fed the nano-iron at higher concentrations showed the best growth performance, stronger immune responses, better antioxidant protection, and healthier intestinal structure. The study suggests that nano-sized iron supplements may be more efficiently absorbed and utilized by fish compared to conventional bulk iron forms.

2023 Biological Trace Element Research 16 citations
Article Tier 2

Effects of polymeric nanoparticles on fish : a multiparametric approach

This study assessed the effects of polymeric nanoparticles on fish using multiple endpoints including growth, reproduction, and gene expression, finding significant biological effects even at low concentrations. The results support the conclusion that plastic nanoparticles pose risks to aquatic vertebrates and provide data relevant to understanding the safety of nanoparticle-containing consumer products.

2017 Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)
Article Tier 2

Construction and analysis of ceRNA networks in the liver of black rockfish (Sebastes schlegelii) following Aeromonas salmonicida infection

Scientists mapped how a fish pathogen infection activates immune responses in the liver of black rockfish, identifying key gene regulatory networks involved in disease defense. The findings could help improve disease management in aquaculture.

2023 Research Square (Research Square)
Article Tier 2

Innate Immunity Provides Biomarkers of Health for Teleosts Exposed to Nanoparticles

This review explores how innate immune biomarkers in fish can be used to assess the health impacts of nanoparticle exposure, finding that immune parameters such as lysozyme activity and complement levels are sensitive indicators of nanoparticle-induced stress. The approach offers tools for monitoring the sublethal effects of nanoplastics and other nanoparticles in aquatic environments.

2019 Frontiers in Immunology 39 citations
Article Tier 2

Transfer and Transcriptomic Profiling in Liver and Brain of European Eels (Anguilla anguilla) After Diet-borne Exposure to Gold Nanoparticles

This study tracked gold nanoparticles through a food chain into European eel liver and brain tissue and examined the transcriptomic responses, finding nanoparticle accumulation triggered gene expression changes related to immune function and lipid metabolism. The research provides insight into how ingested nanoparticles, including nanoplastics, can reach the brain and liver of higher trophic level animals through feeding.

2020 Environmental Toxicology and Chemistry 6 citations
Article Tier 2

Effects of microplastics, pesticides and nano-materials on fish health, oxidative stress and antioxidant defense mechanism

This review examines how microplastics, pesticides, and nanoparticles harm fish by causing oxidative stress, DNA damage, immune system disruption, and changes in gut bacteria. Since contaminated fish is a major pathway for microplastics and pesticides to enter the human diet, declining fish health and quality directly affect food safety and human nutrition worldwide.

2023 Frontiers in Physiology 170 citations
Article Tier 2

Multi biomarker approach to assess manganese and manganese nanoparticles toxicity in Pangasianodon hypophthalmus

Researchers exposed catfish (Pangasianodon hypophthalmus) to manganese and manganese nanoparticles at various concentrations, finding that both forms — especially the nanoparticle form — caused significant oxidative stress, immune disruption, neurochemical changes, and liver and gill damage, with effects worsened at higher water temperatures. The study shows that even essential minerals become toxic in their nanoparticle form or at elevated concentrations, particularly in a warming climate.

2023 Scientific Reports 25 citations
Article Tier 2

Ecotoxicological effects of emerging pollutants (nanomaterials and microplastics) on fish biology

This review compiles current knowledge on how emerging pollutants including nanomaterials and microplastics affect fish biology, covering impacts on physiology, behavior, and molecular function. Researchers highlight that advanced methods like genomics and micro-CT imaging are revealing new details about how these pollutants damage fish at the cellular and tissue level. The study underscores the growing threat these contaminants pose to aquatic ecosystems and the fish species within them.

2025 Animal Reports 2 citations
Article Tier 2

Nano-Enabled Agriculture Using Nano-Selenium for Crop Productivity: What Should be Addressed More?

This review examines the potential of nano-selenium as an agricultural biostimulant, evaluating how selenium nanoparticles may improve crop productivity and seed germination while identifying research gaps in nano-enabled agriculture safety and efficacy.

2023 Environment, Biodiversity and Soil Security 6 citations
Article Tier 2

Selenium toxicity in fishes: A current perspective

This review examines how selenium, a naturally occurring element released by mining and industrial activity, builds up in fish to toxic levels and damages their reproduction, growth, and organ function. While the study focuses on fish toxicity rather than microplastics, it illustrates how environmental pollutants bioaccumulate through aquatic food chains and can ultimately reach humans who consume contaminated seafood.

2024 Chemosphere 22 citations
Article Tier 2

Transcriptome and Gene Family Analyses Reveal the Physiological and Immune Regulatory Mechanisms of Channa maculata Larvae in Response to Nanoplastic-Induced Oxidative Stress

Researchers exposed larvae of blotched snakehead fish to polystyrene nanoplastics at concentrations ranging from 0.05 to 20 mg/L and observed concentration-dependent damage to the liver and intestines. The nanoplastics triggered oxidative stress responses and affected genes involved in immune regulation and detoxification. The study suggests that nanoplastic pollution during early fish development could compromise both organ function and immune defenses.

2026 Antioxidants
Article Tier 2

Advances in Understanding Micro‐ and Nanoplastic Toxicity on Farmed Fish and Emerging Nutritional Interventions

This review examined the toxic effects of micro- and nanoplastics on farmed fish and explored emerging nutritional interventions to mitigate those effects. Researchers found that microplastics reduce feed utilization, cause physical abrasion, and trigger oxidative stress in fish, while certain dietary supplements show promise in enhancing fish resilience against microplastic-related toxicity.

2026 Reviews in Aquaculture
Article Tier 2

Ultrastructural and Proteomic Analyses Revealed the Mechanism by Which Foliar Spraying of Se Nanoparticles Alleviated the Toxicity of Microplastics in Pistia stratiotes L.

Foliar application of selenium nanoparticles to the aquatic plant Pistia stratiotes alleviated toxicity from polyethylene nanoplastics, with ultrastructural and proteomic analyses revealing that selenium nanoparticles protected photosynthetic machinery and antioxidant systems.

2025 Toxics