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61,005 resultsShowing papers similar to Assessing the Safety of Mechanically Fibrillated Cellulose Nanofibers (fib-CNF) via Toxicity Tests on Mice: Single Intratracheal Administration and 28 Days’ Oral Intake
ClearEFSA Project on the use of New Approach Methodologies (NAMs) for the hazard assessment of nanofibres. Lot 1, nanocellulose oral exposure: gastrointestinal digestion, nanofibres uptake and local effects
Researchers used new approach methodologies to assess the potential hazards of nanocellulose materials when consumed orally, focusing on intestinal barrier crossing, local tissue effects, and microbiome interactions. They found that nanocellulose particles were taken up by intestinal cells and that repeated exposure increased uptake, though most effects on gut tissue were mild. The study provides safety-relevant data for the growing use of nanocellulose in food industry applications.
Market competition and risk assessment of nanofiber composite materials
This review examines the market competition and risk assessment landscape for nanocellulose composite materials, which are biodegradable alternatives to conventional plastics for some applications. Replacing plastic with plant-based materials can reduce long-term microplastic accumulation in the environment.
Micro/nanoscaled cellulose from coffee pods do not impact HT-29 cells while improving viability and endosomal compartment after C. jejuni CDT intoxication
Researchers investigated the safety and functional properties of micro/nanoscaled cellulose derived from coffee pods, finding no significant impact on HT-29 intestinal cells while demonstrating improved mechanical and barrier properties relevant to food packaging applications.
Renewable cellulosic nanocomposites for food packaging to avoid fossil fuel plastic pollution: a review
Researchers reviewed how cellulose nanoparticles extracted from plant biomass can replace petroleum-based plastics in food packaging, finding that adding just 1–5% cellulose nanoparticles significantly improves strength, reduces oxygen and water vapor permeability, and keeps packaging biodegradable. The review positions cellulose nanocomposites as a scalable, eco-friendly alternative to fossil-fuel plastics that contribute to microplastic pollution.
Nanocelluloses review: Preparation, biological properties, safety, and applications in the food field
This review examined nanocelluloses — including cellulose nanofibrils, nanocrystals, and bacterial cellulose — as sustainable food ingredients and packaging materials, highlighting their use as edible coatings, emulsion stabilizers, fat substitutes, and prebiotics while noting that safety assessments and regulatory frameworks still require development.
Recent Advances in Cellulose Nanofiber Modification and Characterization and Cellulose Nanofiber-Based Films for Eco-Friendly Active Food Packaging
This review covers advances in cellulose nanofibers, a plant-based material being developed as an eco-friendly alternative to plastic food packaging. These nanofibers are biodegradable, can be extracted from agricultural waste, and can be enhanced with antimicrobial or barrier properties. Replacing conventional plastic packaging with bio-based films like these could help reduce the microplastic contamination that enters the food supply.
Cellulose Nanofiber Platform for Electrochemical Sensor Device: Impedance Measurement Characterization and Its Application for Ethanol Gas Sensor
This review evaluates the evidence for microplastic-associated health risks in humans, synthesizing data from occupational exposure studies, in vitro toxicology, and dietary intake estimates. The authors conclude that current evidence warrants precautionary action, particularly for respiratory and gut exposure routes.
Nanocellulose as Sustainable Bio-Nanomaterial for Packaging and Biomedical Applications
This review examines the potential of nanocellulose, a material derived from plant fibers, as a sustainable alternative to conventional plastics in packaging and biomedical applications. Researchers found that nanocellulose can provide effective moisture and gas barriers when used in paper-based packaging, reducing the need for plastic coatings. The study highlights nanocellulose as a biodegradable, renewable material that could help address both plastic waste and food preservation challenges.
Determination of no observable effect level of nanoplastics on intestinal flora
A 28-day mouse study identified 0.01 mg/kg body weight per day as the maximum no-observable-effect level for nanoplastic exposure when assessing gut microbiome composition — a sensitive early indicator of harm. This is the first study to establish a clear safety threshold for low-dose nanoplastic exposure relevant to realistic human intake levels, providing a foundation for future risk assessments.
In vivo toxicity assessment of microplastics in Balb/C mice : study of inhalation exposure and its inflammatory effects
Researchers examined the in vivo toxicity of inhaled microplastics in Balb/C mice, studying pulmonary inflammation, oxidative stress, and systemic effects following repeated inhalation exposure. The study found dose-dependent lung inflammation and evidence of particle translocation to other organs.
Nanocellulose Bio-Based Composites for Food Packaging
This review explores the use of nanocellulose-based bio-composites as sustainable alternatives to synthetic plastic packaging in the food industry. Researchers found that nanocellulose materials offer improved mechanical strength, barrier properties, and biodegradability compared to conventional plastics. The study highlights how these plant-derived materials could help reduce plastic packaging waste while maintaining food quality and safety standards.
Drying of the Natural Fibers as A Solvent-Free Way to Improve the Cellulose-Filled Polymer Composite Performance
This materials science paper describes how thermal drying of cellulose fibers improves their performance as fillers in polymer composites. Developing stronger plant-fiber composites is part of the broader effort to create biodegradable plastic alternatives that do not generate persistent microplastic pollution.
Human Toxicity of Nano‐ and Microplastics
This review summarizes current evidence on the human toxicity of nano- and microplastics, covering ingestion, inhalation, and dermal exposure routes and the biological effects documented in experimental systems. The authors assess the state of the evidence and identify key gaps for risk characterization.
Nanocellulose-based membrane as a potential material for high performance biodegradable aerosol respirators for SARS-CoV-2 prevention: a review
Researchers reviewed nanocellulose-based membrane materials as biodegradable alternatives to synthetic face mask filters, finding that cellulose nanofibers and nanocrystals offer promising filtration efficiency, biocompatibility, and environmental safety compared to single-use plastic-based respirators.
Preparation and Characterization of Cellulose Nanoparticles from Agricultural Wastes and Their Application in Polymer Composites
Researchers developed eco-sustainable bio-nanocomposite materials by extracting cellulose nanoparticles from agricultural waste such as rapeseed straw, demonstrating their potential as renewable, biodegradable alternatives to synthetic nanomaterials.
A Mini Review of Natural Cellulosic Fibers: Extraction, Treatment and Characterization Methods
This paper is not about microplastics; it reviews methods for extracting, treating, and characterizing natural plant-derived cellulose fibers as sustainable alternatives to synthetic materials in composites and textiles.
Human exposure to micro- and nanoplastic: biological effects and health consequence
This review summarized the biological effects and health consequences of human exposure to micro- and nanoplastics, covering routes of uptake (ingestion, inhalation, dermal), cellular toxicity mechanisms, and systemic health risks identified in recent experimental and epidemiological studies.
Cellulose-Based Materials as a Sustainable Alternative to Plastics: Mitigating Environmental Pollution Through Biodegradability and Reduced Toxicity
This research review shows that materials made from cellulose (the stuff in plant cell walls) could replace regular plastics and help protect human health. Unlike regular plastics that break down into tiny harmful pieces called microplastics that get into our food and water, cellulose materials naturally break down into safe, non-toxic compounds. Making the switch could reduce the plastic pollution that's contaminating our environment and potentially harming our health.
Impacts of Biotechnologically Developed Microorganisms on Ecosystems
Mice given oral microplastic doses for 120 days showed significant damage to liver, kidney, and intestinal tissues along with pathological changes in blood and biochemical markers, while mice exposed for only 28 days showed no significant harm. This finding suggests that the risks of microplastic ingestion may be cumulative over time, and that short-term toxicology studies likely underestimate the health hazard of chronic real-world exposure.
Potential of Nanocellulose for Microplastic removal: Perspective and challenges
Researchers reviewed how nanocellulose — tiny fibers derived from plant cell walls — can capture and remove microplastics from water through its large surface area and adaptable chemistry, positioning it as a promising, naturally biodegradable filter material. While early results are encouraging, further research is needed to optimize how nanocellulose works at scale in real drinking water and wastewater treatment systems.
On the mineralization of nanocellulose to produce functional hybrid materials
Researchers reviewed the mineralization of nanocellulose to create functional hybrid materials, finding that nanocellulose-based building blocks enable a new class of high-performance, sustainable materials through controlled mineral deposition.
No prominent toxicity of polyethylene microplastics observed in neonatal mice following intratracheal instillation to dams during gestational and neonatal period
Researchers administered polyethylene microplastics to pregnant mice via intratracheal instillation during gestation and found no prominent systemic toxicity in neonates at postnatal day 7, though the study used a limited dose range and timeframe.
Shape fidelity and structure of 3D printed high consistency nanocellulose
Researchers developed a method to 3D print high-concentration cellulose nanofibers — a wood-derived, plastic-free material — with precise shape retention, analyzing deformation during drying using 3D scanning and X-ray imaging. This advances the use of sustainable, natural materials in additive manufacturing as potential alternatives to synthetic plastics.
Cellulose Nanofibrils Dewatered with Poly(Lactic Acid) for Improved Bio-Polymer Nanocomposite Processing
This paper is not about environmental microplastics; it describes a manufacturing process for combining cellulose nanofibers with polylactic acid (a biodegradable bioplastic) to make stronger composite materials, with no relevance to plastic pollution or human health risk.