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61,005 resultsShowing papers similar to Development of Water Cluster-Secondary Ion Mass Spectrometry and Particle Induced X-ray Emission to Investigate Spatially Resolved Biological Responses to Nanopolystyrene in Zebrafish Larvae
ClearQualitative and quantitative analysis of accumulation and biodistribution of polystyrene nanoplastics in zebrafish (Danio rerio) via artificial freshwater
Researchers developed MALDI-TOF mass spectrometry methods to accurately track polystyrene nanoplastic accumulation and biodistribution across zebrafish tissues after waterborne exposure, enabling precise quantitative analysis of nanoplastic uptake.
Uptake, bioaccumulation, biodistribution and depuration of polystyrene nanoplastics in zebrafish (Danio rerio)
Researchers used advanced mass spectrometry to track how polystyrene nanoplastics accumulate in and are cleared from zebrafish tissues over time. The nanoplastics concentrated most in the intestine, liver, and gills, with only partial clearance after the exposure ended. This study provides important data on how persistent nanoplastics can be in living organisms, which helps scientists better assess the long-term risks of plastic particle exposure.
Correlative spectroscopy and microscopy analysis of micro- and nanoplastics in complex biological matrices
Researchers combined fluorescence microscopy, second harmonic generation imaging, and coherent Raman scattering to detect and map micro- and nanoplastics in lung cells, zebrafish, and mouse tissues. Polystyrene nanoplastics were found to cross the blood-brain barrier and accumulate in lipid-rich brain regions in animal models.
Quantitative Tracking of Nanoplastic Uptake and Distributionin Zebrafish by Single-Particle Inductively Coupled Plasma Mass Spectrometry
Researchers developed a framework using europium-doped polystyrene nanoplastics as tracers, combined with single-particle inductively coupled plasma mass spectrometry, to quantitatively track nanoplastic uptake and distribution in zebrafish at the single-particle level. This method enabled real-time, size-resolved tracking of nanoplastics accumulating in different fish organs over time.
Quantitative Tracking of Nanoplastic Uptake and Distribution in Zebrafish by Single-Particle Inductively Coupled Plasma Mass Spectrometry
Researchers developed a new method to track nanoplastics at the single-particle level in zebrafish using europium-doped polystyrene particles and mass spectrometry. They found that while most nanoplastics accumulated in the intestine, particles continuously penetrated into internal organs including the brain, demonstrating the ability to cross the blood-brain barrier. The study suggests that nanoplastics pose a systemic exposure risk, though the chorion of fish eggs appears to block their entry.
Uptake Routes and Biodistribution of Polystyrene Nanoplastics on Zebrafish Larvae and Toxic Effects on Development
Researchers exposed zebrafish embryos and larvae to amino-modified polystyrene nanoplastics to study uptake routes and biodistribution. The study found that nanoplastics accumulated in target organs and caused toxic developmental effects, providing evidence that these tiny plastic fragments can penetrate biological barriers and interfere with normal development in aquatic organisms.
Advancing microplastic detection in zebrafish with micro computed tomography: A novel approach to revealing microplastic distribution in organisms
Researchers tested a new approach using X-ray micro-computed tomography (microCT) to detect and map microplastics inside zebrafish in three dimensions. The non-destructive imaging technique successfully identified polyethylene particles throughout the gut and revealed how their distribution changed over time. This method offers a promising alternative to traditional destructive techniques for studying how microplastics move through living organisms.
Biodistribution of europium-doped polystyrene nanoplastics in a model invertebrate organism
This study used europium-doped polystyrene nanoplastics tracked by laser ablation inductively coupled plasma mass spectrometry to map biodistribution of plastic nanoparticles in a model invertebrate organism. The labeled tracer approach enabled precise organ-level mapping of nanoplastic distribution, revealing where plastic nanoparticles accumulate after exposure.
In Situ Identification and Spatial Mapping of Microplastic Standards in Paramecia by Secondary-Ion Mass Spectrometry Imaging
Researchers used secondary-ion mass spectrometry imaging to identify and spatially map microplastic particles inside paramecia, demonstrating that the technique can localize specific polymer types within unicellular organisms at subcellular resolution, offering a new tool for studying how microplastics interact with cell structures.
Pathway analysis of systemic transcriptome responses to injected polystyrene particles in zebrafish larvae
Researchers injected fluorescent polystyrene particles into zebrafish embryos at different developmental stages and tracked their distribution and biological effects using imaging and transcriptomics. Particles injected into the yolk of older embryos spread through the bloodstream and accumulated near the heart, triggering strong immune and inflammatory gene responses. The study reveals that even localized microplastic exposure can produce system-wide biological effects in developing organisms.
Correlative spectroscopy and microscopy analysis of micro- and nanoplastics in complex biological matrices
Researchers combined fluorescence, second harmonic generation, and coherent Raman scattering microscopy in a single instrument to image micro- and nanoplastics in lung cells, zebrafish, and mouse tissues. Polystyrene nanoplastics crossed the blood-brain barrier and accumulated in lipid-rich brain regions in mouse models.
Biodistribution of europium-doped polystyrene nanoplastics in a model invertebrate organism
This study tracked the biodistribution of europium-labeled polystyrene nanoplastics in a model invertebrate using laser ablation ICP-MS, overcoming the analytical challenge of distinguishing nanoplastics from surrounding biological material in tissues. Organ-specific accumulation patterns were mapped, providing mechanistic data on nanoplastic fate after uptake in a small animal model.
Size-dependent and tissue specific accumulation of polystyrene microplastics and nanoplastics in zebrafish
Researchers tracked size-dependent accumulation of polystyrene micro- and nanoplastics in multiple zebrafish tissues, finding that smaller particles distributed more broadly throughout the body compared to larger ones. Nanoplastics showed greater systemic distribution including into brain and reproductive tissues, raising concerns about size-dependent health risks.
Imaging and quantifying the biological uptake and distribution of nanoplastics using a dual-functional model material
Researchers developed a dual-functional nanoplastic model material that allows both imaging and precise quantification of nanoplastic uptake in biological systems. Using surface-enhanced Raman spectroscopy and inductively coupled plasma mass spectrometry, they could track where nanoplastics accumulated in organisms at high resolution. The tool addresses a major gap in nanoplastic research by enabling more accurate measurement of how these tiny particles interact with living tissues.
Uptake, tissue distribution, and toxicity of polystyrene nanoparticles in developing zebrafish (Danio rerio)
Researchers tracked the uptake and distribution of polystyrene nanoparticles in developing zebrafish and found that the particles accumulated in the yolk sac and then spread to the brain, liver, heart, and other organs. While the nanoparticles did not cause significant mortality or deformities, they did reduce heart rate and alter swimming behavior. The study suggests that nanoplastics can penetrate biological barriers and accumulate in multiple tissues during early development.
In situ imaging of microplastics in living organisms based on mass spectrometry technology
Researchers reviewed mass spectrometry-based imaging techniques for detecting microplastics inside living organisms, comparing different ion source methods for their ability to visualize plastic particles in biological tissue. They found that these techniques can provide both spatial distribution maps and chemical composition analysis of microplastics at high resolution. The study suggests that mass spectrometry imaging could become a powerful tool for understanding how microplastics accumulate and distribute within living systems.
Polystyrene nanoplastics (20 nm) are able to bioaccumulate and cause oxidative DNA damages in the brain tissue of zebrafish embryo (Danio rerio)
Researchers microinjected 20-nanometer polystyrene nanoplastics into zebrafish embryos to simulate dietary or maternal exposure and tracked their fate over 120 hours. The study found that nanoplastics reached and bioaccumulated in the brain, causing oxidative DNA damage in the regions where they accumulated. The research team used transmission electron microscopy to image nanoplastics in a vertebrate brain for the first time, also observing increased mortality, developmental abnormalities, and elevated reactive oxygen species.
Using visualization techniques to assess the accumulation of nanoplastics with varying surface modifications
Researchers synthesized fluorescent PMMA nanoplastic particles to study cellular uptake and biodistribution in skin cells and zebrafish embryos, finding that PMMA nanoparticles can enter embryos and accumulate in larval bodies, and highlighting concerns that surface modifications on commercial polystyrene particles may produce misleading results in nanoplastic toxicity studies.
Imaging and quantifying the biological uptake and distribution of nanoplastics using a dual-functional model material
This study used advanced imaging techniques to visualize and quantify nanoplastic uptake and distribution in biological systems, tracking particle translocation from exposure routes into tissues and characterizing intracellular localization.
Localisation and identification of polystyrene particles in tissue sections using Raman spectroscopic imaging
Researchers developed a Raman spectroscopic imaging method to localize and identify polystyrene microplastic particles directly within tissue sections, enabling in-situ detection without fluorescent labeling and making environmental sample analysis feasible.
Quantitative assessment and monitoring of microplastics and nanoplastics distributions and lipid metabolism in live zebrafish using hyperspectral stimulated Raman scattering microscopy
Researchers developed a new imaging technique to watch microplastics and nanoplastics accumulate in live zebrafish in real time, without needing dyes or labels. They found that these tiny plastic particles built up in the fish's digestive system and disrupted fat metabolism, providing direct visual evidence of how micro- and nanoplastics can interfere with basic biological processes.
Synchrotron-based Spectromicroscopy for Microplastic Detection and Characterization
Researchers reviewed how synchrotron-based imaging techniques — which use powerful X-ray beams to see extremely fine details — can detect and chemically identify micro- and nanoplastics that conventional methods miss, including plastics absorbed into biological tissues. These high-resolution tools are still in early stages but show strong potential for mapping microplastic contamination at the nanoscale.
Numerical Study towards In Vivo Tracking of Micro-/Nanoplastic Based on X-ray Fluorescence Imaging
Researchers conducted numerical simulations to evaluate X-ray fluorescence imaging as a method for tracking micro- and nanoplastic particles inside living organisms. The study found that by labeling plastic particles with detectable metal elements, it would be possible to map their distribution across organs with high spatial resolution. The approach could provide precise measurements of how plastic particles cross biological barriers and accumulate in tissues over time.
Mass spectrometry imaging enables detection of MPs and their effects in Daphnia magna following acute exposure
Researchers used an advanced imaging technique called mass spectrometry imaging to track where microplastics accumulate inside water fleas after short-term exposure. They found that the tiny organisms ingested microplastics that concentrated in their gut, and the exposure altered their lipid metabolism. The technique offers a new way to visualize exactly where microplastics end up in small aquatic organisms and what biochemical changes they cause.