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61,005 resultsShowing papers similar to Microplastics: Omnipresent and an ongoing challenge for medical science
ClearImpact of Microplastics and Nanoplastics on Human Health.
This study reports that microplastics and nanoplastics have been found in virtually every tissue in the human body, and emerging research links higher tissue concentrations to several common diseases. The authors note that while exposure sources are well understood and controllable, there appear to be no clinical trials yet focused on removing microplastics from human tissues.
Impact of Microplastics and Nanoplastics on Human Health.
Emerging research shows microplastics and nanoplastics are found in every tissue in the human body, with a positive correlation between tissue concentrations and several common diseases. Despite well-understood exposure sources that can be controlled, no clinical trials have yet been conducted to test methods for eliminating microplastics from human tissues.
Microplastics in Humans: A Critical Review of Biomonitoring Evidence and Immune–Metabolic Associations
This review critically evaluates the current evidence on microplastic detection in human tissues and biological fluids, focusing on methodological challenges and the potential biological mechanisms of action. Researchers found significant variation across studies due to differences in analytical techniques and sample handling protocols. The study highlights emerging evidence linking microplastic presence in the body to immune and metabolic disruptions, while noting that standardized detection methods are urgently needed.
Micro(nano)plastic toxicity and health effects: Special issue guest editorial
Researchers summarized the state of microplastic and nanoplastic toxicology research, noting that while studies in animals show these particles accumulate in tissues and trigger inflammation, oxidative stress, and developmental harm, the actual health risks to humans remain largely unknown and urgently require further investigation.
Growing concerns over ingested microplastics in humans
This paper reviews the growing body of evidence showing that microplastics have been found in various human tissues, raising public health concerns. Researchers note that while laboratory studies demonstrate microplastics can cause cellular damage, significant knowledge gaps remain regarding dose-response relationships, specific target organs, and underlying toxicological mechanisms. The study calls for improved detection technologies and thorough risk assessments to better understand the real-world health implications.
Microplastics and nanoplastics: Exposure and toxicological effects require important analysis considerations
This review highlights that while microplastics and nanoplastics have been found in human tissues and linked to several diseases, the actual toxic effects are still unclear because researchers use very different methods to study them. The authors call for standardized testing approaches so that results can be compared reliably, which is critical for determining what levels of exposure actually pose a risk to human health.
Microplastics in Human Tissues: Sources, Distribution, Toxicological Effects, and Health Implications
Researchers reviewed the growing body of evidence that microplastics accumulate in human tissues — including lung, blood, placenta, breast milk, and heart tissue — where they can trigger inflammation, oxidative stress, and cell death. The review highlights urgent knowledge gaps around how plastic particles move through the body and what their long-term health effects may be.
Morphological and chemical characterization of nanoplastics in human tissue
Researchers developed methods to visualize and chemically characterize nanoplastics that have accumulated in human tissue samples. They were able to identify plastic particles smaller than one micrometer within tissue using advanced microscopy and spectroscopy techniques. The study provides some of the first direct evidence of nanoscale plastic accumulation in the human body, which is essential for designing future health effects research.
Microplastics: challenges of assessment in biological samples and their implication for in vitro and in vivo effects
This review examines the challenges of detecting and assessing microplastics in biological samples, noting that analytical limitations and lack of standardized methods hinder our understanding of health effects. The study highlights that humans are exposed to microplastics primarily through ingestion and inhalation, and that more long-term studies with standardized protocols are needed to understand the full scope of potential biological impacts.
Unveiling the presence of micro and nanoplastics in human biological matrices: A systematic review covering the latest five years from 2020 to 2025
This systematic review covering 2020-2025 confirmed the presence of micro- and nanoplastics in human blood, placenta, lungs, liver, kidneys, and other biological matrices. The findings demonstrate that plastic particles are accumulating in human tissues through ingestion, inhalation, and dermal contact, raising urgent questions about long-term health consequences.
Exposure and Health Effects of Microplastics in Humans
This doctoral thesis investigates exposure levels and health effects of microplastics in humans, synthesizing analytical chemistry and toxicological evidence on microplastic presence in human tissues and their potential biological impacts.
Microplastics: challenges of assessment in biological samples and their implication for in vitro and in vivo effects
This review covers how microplastics enter the human body through ingestion and inhalation, the challenges of detecting and measuring them in biological samples, and the evidence for harmful effects ranging from inflammation to hormonal disruption. Standardising methods for measuring microplastics in tissues and bodily fluids is a key obstacle to advancing human health research. The review provides a useful framework for understanding what we know and what still needs to be established about microplastic risks to people.
Micro(nano)plastics, an emerging health problem
This review frames micro- and nanoplastics as an emerging human health problem, synthesizing evidence of exposure routes, organ-level accumulation, and biological effects, and calling for updated regulatory frameworks to address this novel class of environmental contaminants.
Microplastics: Clinical Trials Perspectives
This mini review covers the current state of clinical research on microplastics in the human body. Tiny plastic particles have been found in human blood and organs, but studying their effects is challenging due to a lack of standardized methods and ethical guidelines for human trials. The paper highlights that while lab and animal studies provide early data, much more work is needed to understand what microplastics do inside us.
Microplastics and human health—an urgent problem
This short commentary draws attention to the ubiquity of microplastic contamination in tap water globally — with studies finding plastics in over 80% of samples worldwide — and urges the medical community to treat microplastics as an urgent public health concern. Sources include synthetic clothing fibers, tire dust, road paint, and the breakdown of larger plastic items.
Methods for the detection of microplastics in mammals
Scientists now detect microplastics in human blood, lungs, placentas, and other tissues, but the field still lacks a single gold-standard method for measuring them. This review compares the strengths and limitations of current detection techniques — including spectroscopy, microscopy, and chemical digestion — to help standardize how microplastics in the human body are quantified, which is a prerequisite for accurately assessing health risks.
The distribution and total burden of microplastics in the human body
This review assessed current knowledge on the distribution and total body burden of nano- and microplastic particles in humans, synthesizing data from external exposure models and internal tissue measurements. The authors identified major uncertainties in estimating total body burden and called for interdisciplinary studies combining exposure modeling with tissue detection to improve risk assessment for microplastics in healthcare.
The landscape of micron-scale particles including microplastics in human enclosed body fluids
Researchers conducted the first comprehensive survey of micron-scale particles, including microplastics, across thirteen types of human body fluids spanning eight organ systems. They detected microparticles in multiple enclosed body fluids, with polyethylene and polyamide among the most common plastic types found. The findings suggest that microplastic exposure in humans is more widespread than previously understood, with particles reaching diverse internal compartments.
The Hidden Health Crisis: Microplastics and Their Medical Consequences
This review summarizes what is known about how microplastics enter the human body through food, water, and air, and the health problems they may cause. Microplastics can carry toxic chemicals like heavy metals and endocrine disruptors, and their physical presence in tissues has been linked to inflammation. The authors stress that doctors should consider microplastic exposure when evaluating chronic conditions, and call for stronger regulations to reduce plastic pollution.
The microplastics time-bomb in our bodies
This piece reports that scientists are increasingly concerned about microplastics — particles smaller than 5mm found throughout our environment, everyday products, and now human bodies — and are warning of potentially grave long-term health consequences.
Knowledge gaps on micro and nanoplastics and human health: A critical review
This critical review assessed current evidence on micro- and nanoplastic exposure and human health, concluding that while humans are ubiquitously exposed via food, water, and air, the long-term health effects of chronic low-level exposure remain poorly understood.
Separation and Detection of Microplastics in Human Exposure Pathways: Challenges, Analytical Techniques, and Emerging Solutions
This review examines the challenges of detecting and measuring microplastics in human tissues and body fluids, where they have been confirmed to exist. Current methods struggle with very small particles (nanoplastics) and lack standardized procedures, making it hard to accurately assess how much plastic is in our bodies. The authors highlight promising new technologies like microfluidic systems and AI-assisted analysis that could improve our ability to measure human exposure.
Why Detecting Nanoplastics in Humans Matters: Exposure Routes, Biological Evidence, and Potential Health Implications
This review summarizes current evidence on nanoplastic detection in human biological samples, including blood, lung tissue, placenta, and brain samples, confirming that human exposure involves internal uptake rather than just environmental contact. The study discusses how ingestion and inhalation are the dominant exposure pathways, while experimental research suggests nanoplastics may induce oxidative stress, inflammation, and endocrine disruption, though direct causal links in humans remain limited.
A critical viewpoint on current issues, limitations, and future research needs on micro- and nanoplastic studies: From the detection to the toxicological assessment.
This critical review examines the current methods for detecting and characterizing micro- and nanoplastics in various environmental samples, as well as reported toxic effects from in vivo and in vitro studies. The authors found that while substantial effort has been made to understand microplastic behavior, the scientific community is still far from a complete understanding of how these particles behave in biological systems. The review calls for improved standardized protocols and more studies focused on uptake kinetics, accumulation, and biodistribution.