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Exposure and Health Effects of Microplastics in Humans
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This doctoral thesis investigates exposure levels and health effects of microplastics in humans, synthesizing analytical chemistry and toxicological evidence on microplastic presence in human tissues and their potential biological impacts.
Programa de Doctorat en Química Analítica i Medi Ambient
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Biochemical Effects of Microplastics on Human Health: A Comprehensive Review
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A comprehensive review documents how microplastics enter the human body through ingestion, inhalation, and skin contact, then reach the lungs, liver, kidneys, brain, and reproductive organs, triggering oxidative stress, inflammation, endocrine disruption, and genotoxicity. These biochemical pathways link microplastic exposure to serious chronic conditions including metabolic syndrome, neurodegenerative disease, reproductive dysfunction, and cancer.
Microplastics and Human Health: A Comprehensive Review on Exposure Pathways, Toxicity, and Emerging Risks
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This comprehensive review examines microplastic exposure pathways in humans, methods of detection, and the potential toxic effects on various biological systems. The study highlights growing evidence that microplastics can enter the body through ingestion, inhalation, and dermal contact, and may affect multiple organ systems, though significant uncertainties remain about long-term health outcomes.
Plastics, microplastics, and human contamination: A literature review
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This literature review synthesizes research on human contamination by plastics and microplastics, covering ingestion, inhalation, and dermal exposure routes and summarizing documented health effects across organ systems.
Impact of Microplastic Exposure on Human Health: A Systematic Review of Mechanisms, Biomarkers, and Clinical Outcomes
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This systematic review found that microplastics have been detected in human blood, placental tissue, and gastrointestinal samples, with proposed health mechanisms including oxidative stress, chronic inflammation, endocrine disruption, and gut microbiome alterations. While direct clinical evidence remains limited, the accumulating laboratory and observational data point to microplastics as a plausible contributor to multiple disease pathways.
Potential Health Impact of Microplastics: A Review of Environmental Distribution, Human Exposure, and Toxic Effects
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This review summarizes existing research on how microplastics are found throughout the environment and in human samples, entering the body through food, air, and skin contact. Lab studies in cells and animals show microplastics can cause oxidative stress, DNA damage, immune reactions, brain toxicity, and reproductive harm, and early human health data links microplastic exposure to several chronic diseases.
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