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61,005 resultsShowing papers similar to Oxidative stress and metabolic process responses of Chlorella pyrenoidosa to nanoplastic exposure: Insights from integrated analysis of transcriptomics and metabolomics
ClearTranscriptome analysis of the toxic mechanism of nanoplastics on growth, photosynthesis and oxidative stress of microalga Chlorella pyrenoidosa during chronic exposure
Researchers studied the chronic effects of nanoplastics on a freshwater microalga and found a surprising dual response: growth was initially inhibited during the first two weeks but then promoted at lower concentrations over longer exposure. Gene expression analysis revealed that the initial toxicity stemmed from suppressed protein synthesis, while the later recovery involved the algae ramping up cell division and stress defense mechanisms. The study provides molecular-level insights into how aquatic microorganisms may adapt to ongoing nanoplastic exposure.
Integrating transcriptomics and biochemical analysis to understand the interactive mechanisms of the coexisting exposure of nanoplastics and erythromycin on Chlorella pyrenoidosa
Researchers used transcriptomics and biochemical analysis to study how nanoplastics and the antibiotic erythromycin interact when both are present in water with the green alga Chlorella pyrenoidosa. They found that the combined toxicity was dynamic, shifting from synergistic to antagonistic effects depending on nanoplastic concentration and exposure duration. The study indicates that co-exposure disrupts algal cell membranes, induces oxidative stress, and reduces photosynthetic efficiency.
The Growth Inhibition of Polyethylene Nanoplastics on the Bait-Microalgae Isochrysis galbana Based on the Transcriptome Analysis
Researchers found that polyethylene nanoplastics (50 nm) significantly inhibited growth and reduced chlorophyll in the bait microalga Isochrysis galbana through oxidative stress and disrupted gene expression, while larger microplastics had no significant impact.
Nanoplastics reshape lipid metabolism in marine microalgae with potential ecological consequence
Researchers exposed a marine microalga important to ocean ecosystems to nanoplastics and found significant disruptions to its lipid metabolism, reducing both biomass and lipid production. The nanoplastics altered the types of fats the algae produced, potentially affecting the nutritional value of these organisms for the marine food web. The findings suggest that nanoplastic pollution could have cascading ecological consequences by disrupting carbon cycling at the base of the food chain.
Understanding nanoplastic toxicity and their interaction with engineered cationic nanopolymers in microalgae by physiological and proteomic approaches
Physiological and proteomic analysis of microalgae exposed to polystyrene nanoplastics and PAMAM dendrimers singly and combined revealed novel toxicity mechanisms including protein expression changes and identified potential biomarkers for nanopolymer exposure in aquatic primary producers.
Unveiling the molecular mechanisms of size-dependent effect of polystyrene micro/nano-plastics on Chlamydomonas reinhardtii through proteomic profiling
Researchers used proteomic profiling to uncover the molecular mechanisms behind how different sizes of polystyrene micro- and nanoplastics affect the green alga Chlamydomonas reinhardtii. They found that particle size plays a critical role in determining the type and severity of biological responses in the algae. The study suggests that nanoscale plastic particles may pose distinct ecological risks compared to larger microplastics due to their ability to trigger different cellular stress pathways.
Molecular mechanism for combined toxicity of micro(nano)plastics and carbon nanofibers to freshwater microalgae Chlorella pyrenoidosa
Researchers tested how microplastics, nanoplastics, and carbon nanofibers affect freshwater algae individually and in combination, finding that the combined effects were significantly worse than either pollutant alone. Nanoplastics combined with carbon nanofibers caused the most severe cellular stress, damaging cell membranes, increasing oxidative stress, and disrupting energy metabolism. Since algae form the base of aquatic food chains, this damage could cascade through ecosystems and affect the safety of water and seafood for humans.
The response of Synechococcus sp. PCC 7002 to micro-/nano polyethylene particles - Investigation of a key anthropogenic stressor
Researchers investigated the molecular responses of the marine cyanobacterium Synechococcus sp. PCC 7002 to polyethylene micro- and nanoparticles, finding that these anthropogenic stressors altered gene expression and physiological processes in this key marine photosynthetic organism.
Microplastics disrupt microalgal carbon fixation: Efficiency and underlying mechanisms
Researchers exposed the microalga Chlorella pyrenoidosa to polyethylene and polyvinyl chloride microplastics and found up to 39% inhibition of carbon fixation, driven by reduced chlorophyll content, increased oxidative stress, and downregulation of genes in the Calvin cycle and chlorophyll metabolism, with implications for aquatic carbon cycling.
Mechanism of the inhibition and detoxification effects of the interaction between nanoplastics and microalgae Chlorella pyrenoidosa
Researchers exposed green algae to nanoplastics and observed an unexpected pattern: the algae were initially inhibited but gradually recovered over time. At the molecular level, nanoplastics initially blocked protein synthesis and damaged DNA, reducing algal growth and photosynthesis. However, the algae activated detoxification mechanisms including accelerated cell division and degradation of damaged cellular components, suggesting these organisms have some capacity to adapt to nanoplastic stress.
Micro/nano-plastics and microalgae in aquatic environment: Influence factor, interaction, and molecular mechanisms.
This review examined the interactions between micro/nanoplastics and microalgae in aquatic environments, summarizing how plastic particle size, surface chemistry, and co-pollutants influence algal toxicity through oxidative stress, photosynthesis inhibition, and gene expression changes.
The mechanism of oxidative stress induced by nanoplastics in Caenorhabditis elegans: Integrated analysis of transcriptomics and metabolomics
Researchers exposed C. elegans nematodes to polystyrene nanoplastics across a concentration range and integrated transcriptomic and metabolomic data to identify disrupted fatty acid and glutathione metabolism as the central drivers of oxidative stress, with the gene gst-4 and specific metabolites serving as key molecular signatures.
Nanoplastics exposure modulate lipid and pigment compositions in diatoms
Researchers exposed marine diatoms (Chaetoceros neogracile) to amine-functionalized polystyrene nanoplastics and found disruption to photosynthetic pigments and membrane lipid composition, with exponential-phase cells showing impaired long-chain fatty acid synthesis at high concentrations — identifying lipid and pigment profiles as sensitive biomarkers for nanoplastic stress in marine primary producers.
Unravelling the toxicity mechanisms of polystyrene nanoplastics on physiological and transcriptomic responses of the marine dinoflagellate Alexandrium minutum
Researchers exposed the toxic marine dinoflagellate Alexandrium minutum to polystyrene nanoplastics at concentrations from 0.1 to 50 mg/L and measured physiological responses and toxin production. NP exposure inhibited growth and photosynthesis, altered gene expression, and changed the profile of paralytic shellfish toxins produced by the alga.
[Physiological and Ecological Response Characteristics and Transcriptomic Change Characteristics of Rice （Oryza sativa）Under Different Microplastic Stresses].
Researchers used transcriptomic analysis to characterize physiological and ecological response characteristics of an aquatic organism exposed to microplastic stress, identifying gene expression changes in pathways related to immune function, oxidative stress, and energy metabolism.
Calcium-mediated mitigation of aged nanoplastic-induced stress in microalgae: Insights into photosynthesis, energy metabolism, and antioxidant defense from physiological and multi-omics analyses
Scientists found that tiny plastic particles (nanoplastics) severely damage microalgae, which are important organisms used to clean wastewater before it enters our water supply. However, adding calcium to the water protected the microalgae from this plastic pollution and helped them continue removing harmful substances from wastewater. This research suggests calcium could help maintain clean water treatment systems even as plastic pollution increases in our environment.
Proteomic insights into composition-dependent effects of microplastics on freshwater microalgae Chlamydomonas reinhardtii
Researchers used proteomic analysis to study how different types of microplastics affect freshwater green algae at the molecular level. They found that the chemical composition of microplastics influences which cellular pathways are disrupted. The study provides new insights into the specific molecular mechanisms behind microplastic toxicity in aquatic organisms.
Distinguish the toxic differentiations between acute exposure of micro- and nano-plastics on bivalves: An integrated study based on transcriptomic sequencing
Researchers found that nanoplastics are more toxic than microplastics in mussels, causing severe inflammatory responses and greater oxidative stress, with transcriptomic analysis revealing contrasting gene expression patterns between the two particle sizes.
Micro/nanoplastic-induced stress in microalgae: Latest laboratory evidence and knowledge gaps
This review compiled laboratory evidence on how micro- and nanoplastics stress microalgae — the base of aquatic food webs — covering effects on photosynthesis, growth, oxidative stress, and toxin production. The authors identify key knowledge gaps including environmentally realistic concentrations and combined contaminant effects.
Toxicity of microplastics and nano-plastics to coral-symbiotic alga (Dinophyceae Symbiodinium): Evidence from alga physiology, ultrastructure, OJIP kinetics and multi-omics
Researchers studied how microplastics and nanoplastics damage Symbiodinium, the algae that live inside coral and keep reefs alive. Even at concentrations found in the real environment, the plastic particles disrupted photosynthesis, caused oxidative stress, and triggered metabolic problems in the algae. Since the breakdown of this coral-algae partnership leads to coral bleaching, microplastic pollution could threaten the reef ecosystems that support fisheries and coastal communities worldwide.
Polystyrene nanoplastic induces oxidative stress, immune defense, and glycometabolism change in Daphnia pulex: Application of transcriptome profiling in risk assessment of nanoplastics
Researchers used transcriptome sequencing to examine how polystyrene nanoplastics affect gene expression in the water flea Daphnia pulex. After 96 hours of exposure, they identified 208 genes with altered expression levels, linked to oxidative stress, immune defense, and sugar metabolism pathways. The study provides molecular-level evidence that nanoplastic pollution can trigger multiple stress responses in freshwater organisms.
Metabolism deficiency and oxidative stress induced by plastic particles in the rotifer Brachionus plicatilis: Common and distinct phenotypic and transcriptomic responses to nano- and microplastics
Researchers found that nanoplastics caused stronger reproductive and population growth inhibition in the marine rotifer Brachionus plicatilis than microplastics, with transcriptomic analysis revealing distinct size-dependent toxicity pathways involving metabolism deficiency and oxidative stress.
Evaluating the Single and Combined Effects of BMDM and PS Microplastics on Chlorella sp.: Physiological and Transcriptomic Insights
Researchers exposed the alga Chlorella sp. to a UV-absorber chemical (BMDM) and polystyrene microplastics individually and in combination, finding that combined exposure produced an antagonistic effect—less total cellular and gene expression disruption than either stressor alone.
Genome-Wide Molecular Adaptation in Algal Primary Productivity Induced by Prolonged Exposure to Environmentally Realistic Concentration of Nanoplastics
Researchers exposed algae to three types of nanoplastics at realistic environmental levels for 100 days and found the algae adapted by increasing their numbers and photosynthetic activity. However, this adaptation came with significant changes in gene expression and DNA modification patterns, meaning the nanoplastics fundamentally altered the algae's biology. Since algae are the foundation of aquatic food chains, these hidden molecular changes could have ripple effects through ecosystems that eventually affect human food sources.