We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Papers
61,005 resultsDetection of nanoplastics in food by asymmetric flow field-flow fractionation coupled to multi-angle light scattering: possibilities, challenges and analytical limitations
Researchers tested whether asymmetric flow field-flow fractionation coupled to light-scattering detection could identify nanoplastics in fish tissue, successfully detecting 100 nm polystyrene particles at a limit of 52 µg/g after enzymatic digestion, but found the method could not be directly transferred to polyethylene particles without further adjustment.
A method for efficient separation of polystyrene nanoplastics and its application in natural freshwater
Researchers developed a method using asymmetrical flow field-flow fractionation (AF4) coupled with multiple detectors to efficiently separate and characterize polystyrene nanoplastics by particle size in freshwater environments, demonstrating its applicability for analysing nanoplastic environmental behaviour in natural freshwater samples.
In-house validation of AF4-MALS-UV for polystyrene nanoplastic analysis
Researchers validated an asymmetric flow field-flow fractionation method coupled with multi-angle light scattering and UV detection for simultaneously sizing and quantifying polystyrene nanoplastics from 20 to 200 nm, achieving greater than 90% recovery and detection limits of 15–33 µg/mL across a polydisperse nanoplastic mixture.
Extraction and quantification of polystyrene nanoplastics from biological samples
Researchers developed a new method to extract and quantify polystyrene nanoplastics from biological samples using alkaline digestion, centrifugation, cloud point extraction, and single-particle ICP-MS with gold nanoparticle labeling. The method achieved recovery rates above 80% and was validated in tissue samples, addressing a major analytical gap for nanoplastic detection in complex biological matrices.
Validated method for polystyrene nanoplastic separation in aqueous matrices by asymmetric-flow field flow fraction coupled to MALS and UV–Vis detectors
Researchers developed and fully validated a method to accurately measure nanoplastic particle sizes (30–490 nm) in water using a technique that combines flow separation with light-scattering detection. Having a validated analytical method is a critical step for standardizing how nanoplastics are measured across laboratories, enabling more consistent assessment of their environmental risks.
Thermal fragmentation enhanced identification and quantification of polystyrene micro/nanoplastics in complex media
Researchers developed a method using thermal fragmentation combined with MALDI-TOF mass spectrometry to identify and quantify polystyrene micro/nanoplastics in complex media, enabling reliable fingerprint-based detection and quantification down to nanoplastic size ranges.
Quantitative Analysis of Polystyrene and Poly(methyl methacrylate) Nanoplastics in Tissues of Aquatic Animals
Researchers developed a new method to detect and measure nanoplastics in the tissues of aquatic animals with high sensitivity. Using a combination of tissue digestion and pyrolysis gas chromatography-mass spectrometry, they achieved detection limits as low as 0.03 micrograms per gram for polystyrene nanoplastics. When they tested 14 aquatic animal species, polystyrene nanoplastics were found in three of them, demonstrating that nanoplastic contamination is present in real-world wildlife.
An effective solution to simultaneously analyze size, mass and number concentration of polydisperse nanoplastics in a biological matrix: asymmetrical flow field fractionation coupled with a diode array detector and multiangle light scattering
Researchers developed an asymmetrical flow field-flow fractionation method coupled with a diode array detector and multiangle light scattering to simultaneously measure the size, mass, and number concentration of polydisperse nanoplastics in biological matrices, providing a more accurate tool for assessing nanoplastic pollution levels.
IntegratingAF4 and Py-GC-MS for Combined Size-ResolvedPolymer-Compositional Analysis of Nanoplastics with Application toWastewater
Researchers developed a novel workflow for nanoplastic characterization in environmental water samples by integrating asymmetric flow field-flow fractionation with multiangle light scattering (AF4-MALS) and pyrolysis-gas chromatography-mass spectrometry (Py-GC-MS) in an offline combination. This approach enables simultaneous size-resolved and polymer-compositional analysis of nanoplastics in wastewater, addressing the lack of standardized methods for this challenging contaminant class.
Integrating AF4 and Py-GC-MS for Combined Size-Resolved Polymer-Compositional Analysis of Nanoplastics with Application to Wastewater
This study combined asymmetric flow field-flow fractionation with multiangle light scattering and pyrolysis-GC-MS in an offline workflow to simultaneously characterize nanoplastic size distribution (down to ~1 nm) and polymer composition in wastewater, offering a new standard-compatible approach for environmental nanoplastic analysis.
A novel extraction protocol of nano-polystyrene from biological samples
Researchers developed a diatomite-based extraction protocol for isolating nano-polystyrene from biological samples, providing a method to quantify nanoplastics in tissues that had previously lacked reliable analytical tools.
Characterization of Nanoparticles in Drinking Water Using Field-Flow Fractionation Coupled with Multi-Angle Light Scattering and Inductively Coupled Plasma Mass Spectrometry
Researchers developed methods using field-flow fractionation coupled with multi-angle light scattering and mass spectrometry to characterize nanoparticles in drinking water. The study addresses the lack of standardized techniques for detecting submicrometer particles, including nanoplastics, highlighting the need for better analytical tools to monitor emerging water contaminants.
Development of a silica gel chromatography-based cleanup method for quantification of polystyrene nanoplastics in tissue samples via pyrolysis–GC/MS
Researchers developed a silica gel chromatography cleanup method to eliminate biological matrix interference and enable accurate quantification of polystyrene nanoplastics in animal tissue samples using pyrolysis-GC/MS, addressing a key methodological barrier in nanoplastic bioaccumulation research.
Isolation and Quantification of Polystyrene Nanoplastics in Tissues by Low Pressure Size Exclusion Chromatography
Researchers developed a size exclusion chromatography method to isolate and quantify polystyrene nanoplastics (50 and 100 nm) from biological tissue homogenates using fluorescent dye detection and salting-out concentration. The method was validated in tissue from clams from a high-traffic harbor and freshwater mussels downstream of an urban area.
Finding the tiny plastic needle in the haystack: how field flow fractionation can help to analyze nanoplastics in food
This review assessed field flow fractionation (FFF) as an analytical method for detecting and characterizing nanoplastics in food, noting that conventional techniques lack the resolution to identify nano-sized plastic particles in complex food matrices. FFF was identified as a promising tool for generating the exposure data needed for nanoplastic risk assessment.
A new insight of size-dependent plastics particles kinetics with regarding of metabolomics effects in liver and kidney
Researchers developed a comprehensive extraction and detection protocol to track polystyrene particles of three sizes (80 nm, 2 µm, and 20 µm) across multiple organs in exposed animals, finding that smaller particles accumulated more broadly — reaching the brain, liver, spleen, and kidney — while liver and kidney metabolism was disrupted in size-dependent but distinct ways.
Identification of polystyrene nanoplastics from natural organic matter in complex environmental matrices by pyrolysis–gas chromatography–mass spectrometry
Researchers used pyrolysis-gas chromatography-mass spectrometry to identify polystyrene nanoplastics in environmental samples containing natural organic matter, developing methods to distinguish nanoplastic signals from complex organic background matrices in water.
Label-free nano- and microplastics detection in mammalian tissue by photothermal infrared spectroscopy
Researchers applied optical photothermal infrared spectroscopy to detect and identify nano- and microplastics smaller than 1 µm in mammalian tissue sections without requiring labels or lengthy digestion protocols. The method successfully localized polystyrene particles in tissue samples with chemical specificity, offering a faster workflow for nanoplastic detection in biological matrices.
Correlative spectroscopy and microscopy analysis of micro- and nanoplastics in complex biological matrices
Researchers combined fluorescence microscopy, second harmonic generation imaging, and coherent Raman scattering to detect and map micro- and nanoplastics in lung cells, zebrafish, and mouse tissues. Polystyrene nanoplastics were found to cross the blood-brain barrier and accumulate in lipid-rich brain regions in animal models.
A novel platform using a regenerable SDS-functionalized membrane with AF4-DAD-MALS for online-operated enrichment and detection of polydisperse nanoplastics in biological samples
This study developed a novel analytical platform combining an SDS-functionalized membrane with asymmetric flow field-flow fractionation to detect and characterize nanoplastics in biological samples. The method enabled online enrichment and size-resolved detection of polydisperse nanoplastics at concentrations relevant to health exposure assessments.
Uptake, bioaccumulation, biodistribution and depuration of polystyrene nanoplastics in zebrafish (Danio rerio)
Researchers used advanced mass spectrometry to track how polystyrene nanoplastics accumulate in and are cleared from zebrafish tissues over time. The nanoplastics concentrated most in the intestine, liver, and gills, with only partial clearance after the exposure ended. This study provides important data on how persistent nanoplastics can be in living organisms, which helps scientists better assess the long-term risks of plastic particle exposure.
Tissue Distribution of Polystyrene or Mixed Polymer Microspheres and Metabolomic Analysis after Oral Exposure in Mice.
Mice orally exposed to polystyrene or mixed polymer microspheres showed plastic particle distribution across multiple tissues including the liver, kidney, and spleen, with metabolomic analysis revealing distinct alterations in lipid, amino acid, and energy metabolism pathways.
Online Coupling of Field-Flow Fractionation with Raman Microspectroscopy Enables the Advanced Study of Nanoplastics Directly in Food
Researchers developed an online coupling of field-flow fractionation with Raman microspectroscopy to enable direct detection and characterisation of nanoplastics in complex food matrices, overcoming limitations of existing methods that require laborious sample preparation.
Asymmetric flow field-flow fractionation coupled with inductively coupled plasma mass spectrometry for quality control of the grafting state of polystyrene on gold nanoparticles
Researchers synthesized gold nanoparticles coated with polystyrene as electron-microscopy-visible proxies for nanoplastics in cells, then used asymmetric flow field-flow fractionation coupled with mass spectrometry to precisely characterize the grafting percentage and size distribution of the hybrid particles, enabling clearer visualization of nanoplastic uptake in biological tissue.