Papers

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Article Tier 2

Effects of ingested microplastic particles on susceptibility of chironomid midges to the insecticide spinosad compared to Bacillus thuringiensis israelensis

This study tested whether ingested polyethylene microplastics alter the toxicity of spinosad (a neurotoxic insecticide) to chironomid midge larvae, extending earlier work that found mixed effects with Bti. Larger particles (125 µm) increased spinosad toxicity while smaller particles (34-50 µm) reduced it, pointing to size-dependent interactions between microplastics and pesticide toxicity.

2025 Hydrobiologia
Article Tier 2

Size over substance: Microplastic particle size drives gene expression and fitness loss in a freshwater insect

Researchers exposed freshwater midge larvae to polyamide and polyvinyl chloride microplastics of different sizes and found that particle size mattered more than plastic type in determining harm. Smaller microplastics triggered stronger stress responses at the gene level, including oxidative stress and immune activation, and caused greater reductions in reproduction and survival. The findings suggest that size should be a primary consideration when assessing microplastic risks to aquatic life.

2025 Aquatic Toxicology 4 citations
Article Tier 2

Toxicity of microplastics and natural particles in the freshwater dipteran Chironomus riparius: Same same but different?

Larvae of the freshwater midge Chironomus riparius were chronically exposed to PVC microplastics and natural particles (kaolin, diatomite) alone and combined with the pesticide imidacloprid for 28 days, with effects observed only at high PVC concentrations but with interactions noted between particles and the insecticide. The study suggests that natural particles are not consistently more benign than microplastics at equal concentrations.

2019 The Science of The Total Environment 101 citations
Article Tier 2

Microplastic Interference with Fipronil Toxicity to Zebrafish Embryonic Development

Researchers studied how polyethylene microplastics affect the toxicity of the insecticide fipronil on developing zebrafish embryos. They found that while microplastics reduced the lethal effects of fipronil, likely by adsorbing some of the chemical, they did not change the rate of developmental abnormalities. The study highlights the complex ways different pollutants can interact in aquatic environments.

2024 Microplastics 5 citations
Article Tier 2

Downsizing plastics, upsizing impact: How microplastic particle size affects Chironomus riparius bioturbation activity

This study tested how different sizes of polyethylene microplastics affect the burrowing behavior of freshwater midge larvae, which play an important role in mixing and aerating lake and river sediments. Smaller microplastics were ingested more readily and disrupted the larvae's sediment-mixing activity more than larger particles. Since these organisms are critical for healthy freshwater ecosystems, the findings suggest that small microplastics could disrupt nutrient cycling in lakes and rivers.

2025 Environmental Research 9 citations
Article Tier 2

Polystyrene Microplastics Modulate the Toxicity of the Hydrophilic Insecticide Thiacloprid for Chironomid Larvae and Also Influence Their Burrowing Behavior

Researchers found that polystyrene microplastics altered the toxicity of the hydrophilic insecticide thiamethoxam to aquatic invertebrates, with the combined exposure producing different effects than either stressor alone. The study highlights that microplastics can act as vectors that change the bioavailability and ecotoxicological impact of water-soluble pesticides.

2022 Microplastics 8 citations
Article Tier 2

Mechanisms influencing the impact of microplastics on freshwater benthic invertebrates: Uptake dynamics and adverse effects on Chironomus riparius

Researchers studied the factors influencing microplastic uptake and toxicity in the freshwater midge Chironomus riparius using experimental data and agent-based modeling. They found that high concentrations of small microplastics fill the insect gut, are eliminated more slowly than natural particles, and cause damage to gut tissue that leads to reduced growth and delayed development. The study suggests that microplastic concentrations in some freshwater hotspots may already be high enough to cause adverse effects in wild populations.

2022 The Science of The Total Environment 54 citations
Article Tier 2

Effect of microplastics on ecosystem functioning: Microbial nitrogen removal mediated by benthic invertebrates

Researchers investigated how polyethylene microplastics affect nitrogen removal in freshwater sediments where chironomid larvae and microorganisms coexist. They found that while microplastics and larvae each individually promoted nitrogen removal by boosting denitrifying bacteria, combining them together produced less benefit than expected. The study suggests that rising microplastic concentrations may disrupt the natural nitrogen cycling that benthic invertebrates help maintain in freshwater ecosystems.

2020 The Science of The Total Environment 139 citations
Article Tier 2

Microplastics enhance Daphnia magna sensitivity to the pyrethroid insecticide deltamethrin: Effects on life history traits

Researchers tested whether polyethylene microplastics alter the toxicity of the pyrethroid insecticide deltamethrin to Daphnia magna and found that microplastic presence increased sensitivity to deltamethrin, reducing survival and reproductive output at concentrations that were not toxic without microplastics.

2020 The Science of The Total Environment 100 citations
Article Tier 2

The particle effect: comparative toxicity of chlorpyrifos in combination with microplastics and phytoplankton particles in mussel

Researchers compared how microplastics and natural phytoplankton particles each affect the toxicity of the pesticide chlorpyrifos in mussels. They found that both particle types adsorbed the pesticide and transferred it to the mussels, but the biological effects differed depending on the carrier. The study suggests that microplastics are not uniquely dangerous as pollutant carriers, since natural particles in the environment can play a similar role in shuttling chemicals into marine organisms.

2024 Aquatic Toxicology 7 citations
Article Tier 2

Multigenerational effects of polyethylene microplastics on freshwater benthic invertebrates, Chironomus tepperi

Researchers exposed the freshwater benthic midge Chironomus tepperi to polyethylene microplastics (8-20 µm) in sediment at four environmentally relevant concentrations over two generations, finding no significant effects on growth but significant decreases in survival and emergence rates at the highest concentration (1,000 MPs/kg) in both generations. Metabolic analyses were conducted to further characterize sublethal mechanisms of MP toxicity in this common stormwater sediment organism.

2022 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

Nanoplastics modulate the outcome of a zooplankton–microparasite interaction

Researchers found that nanoplastics can alter the outcome of zooplankton-microparasite interactions, demonstrating that plastic pollution at the nanoscale may disrupt host-parasite dynamics in freshwater ecosystems with cascading ecological effects.

2023 Freshwater Biology 13 citations
Article Tier 2

Combined effects of polyethylene microplastics and natural stressors on Chironomus riparius life-history traits

Researchers examined combined effects of polyethylene microplastics with temperature, salinity, and food stress on the midge Chironomus riparius, finding that microplastic effects on life-history traits were modulated by these natural stressors in ways not predicted by simple additive models.

2022 Environmental Research 22 citations
Article Tier 2

Single and combined effects of microplastics, pyrethroid and food resources on the life-history traits and microbiome of Chironomus riparius

Researchers exposed Chironomus riparius larvae to microplastics alone and combined with a pyrethroid pesticide under varying food conditions, finding that combined stress altered life-history traits and shifted the gut microbiome composition, with food availability modulating the severity of effects.

2021 Environmental Pollution 47 citations
Article Tier 2

The response of life history defense of cladocerans under predation risk varies with the size and concentration of microplastics

Microplastics at two particle sizes (0.7 and 1 micrometer) were found to interfere with anti-predation defense responses in two cladoceran species, with effects on life history traits depending on microplastic concentration and body size of the organism, highlighting complex ecological interactions in contaminated freshwater.

2021 Journal of Hazardous Materials 53 citations
Article Tier 2

Ingestion of small-sized and irregularly shaped polyethylene microplastics affect Chironomus riparius life-history traits

Researchers exposed freshwater midge larvae to irregularly shaped polyethylene microplastics of different size classes and found that larvae preferentially ingested the smallest particles (32-63 micrometers) regardless of what sizes were available. Ingestion of these small particles significantly reduced larval growth and delayed adult emergence at relatively low concentrations. The findings suggest that small, irregularly shaped microplastics, which are the most common form in natural sediments, may pose a greater risk to benthic organisms than larger particles.

2019 The Science of The Total Environment 171 citations
Article Tier 2

Combined ecotoxicological effects of different-sized polyethylene microplastics and imidacloprid on the earthworms (Eisenia fetida)

Researchers exposed earthworms to different sizes of polyethylene microplastics combined with the pesticide imidacloprid and found that particle size significantly influenced the combined toxic effects. Smaller microplastics tended to increase pesticide toxicity more than larger ones, affecting earthworm survival, growth, and antioxidant responses. The findings highlight how microplastic size matters when assessing the joint environmental risks of plastic pollution and agricultural chemicals in soil.

2023 The Science of The Total Environment 56 citations
Article Tier 2

Understanding the microplastic pollution impact on Chironomus sancticaroli larvae development and emergence

Researchers studied how PET microplastics affect the development and emergence of Chironomus midge larvae, an important freshwater insect. They found that microplastic exposure altered larval development and reduced successful adult emergence. The study suggests that microplastic pollution in freshwater ecosystems could disrupt the life cycles of aquatic insects, which are vital to food webs and ecosystem health.

2024 Knowledge and Management of Aquatic Ecosystems 4 citations
Article Tier 2

Microplastics reduce the bioaccumulation and oxidative stress damage of triazole fungicides in fish

Researchers found that microplastics can reduce the bioaccumulation and oxidative stress damage of triazole fungicides in fish, suggesting that microplastic-pesticide interactions may alter the expected toxicity of agricultural chemicals in aquatic organisms.

2021 The Science of The Total Environment 45 citations
Article Tier 2

Size-dominated biotoxicity of microplastics laden with benzophenone-3 and ciprofloxacin: Enhanced integrated biomarker evaluation on mussels

Researchers found that smaller microplastics laden with benzophenone-3 and ciprofloxacin caused greater toxicity in mussels than larger particles, demonstrating that particle size is the dominant factor driving the combined biotoxicity of microplastics and adsorbed contaminants.

2023 Environmental Pollution 7 citations
Article Tier 2

Microplastics modify the toxicity of glyphosate on Daphnia magna

Daphnia magna were exposed to three glyphosate formulations combined with polyethylene microbeads or PET/PA fibers for one week, finding that microplastics altered (mostly reduced) the toxicity of glyphosate depending on formulation and plastic type. The study demonstrates that microplastics can modulate pesticide bioavailability and toxicity in freshwater crustaceans.

2019 The Science of The Total Environment 107 citations
Article Tier 2

Toxicity of mixture of polyethylene microplastics and Up Grade® pesticide on Oreochromis niloticus juvenile: I. Hemato-biochemical and histopathological alterations

Researchers exposed juvenile Nile tilapia to a pesticide and polyethylene microplastics, both individually and in combination, and measured blood chemistry changes and organ damage over 15 days. The combination treatment caused more severe effects than either pollutant alone, including reduced red blood cell counts, elevated liver enzymes, and significant tissue damage to the gills and intestines. The study demonstrates that microplastics can worsen the toxic effects of agricultural pesticides on commercially important fish species.

2023 Environmental Toxicology and Pharmacology 21 citations
Article Tier 2

Effects of microplastics and nanoplastics on host–parasite interactions in aquatic environments

Researchers reviewed how microplastics and nanoplastics affect the interactions between parasites and their hosts in aquatic environments. Evidence indicates that plastic particles can influence infection rates, parasite transmission, and host immune responses, though the effects vary widely depending on the species and type of plastic involved.

2024 Oecologia 7 citations
Article Tier 2

Interactions of Microplastics with Freshwater Biota

Researchers reviewed how microplastics affect freshwater animals, finding that toxicity depends on a complex mix of factors including plastic type, size, shape, chemical additives, and microbial coatings — and emphasizing that future studies need to compare synthetic plastic effects against natural particles to understand what truly makes microplastics harmful.

2017 ˜The œhandbook of environmental chemistry 155 citations