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61,005 resultsShowing papers similar to Concerning influences of micro/nano plastics on female reproductive health: focusing on cellular and molecular pathways from animal models to human studies
ClearA review of the impact of micro‐ and nanoplastics on female reproduction: What we know and gaps in knowledge
This review examines what is known about how micro- and nanoplastics affect female reproductive health. Animal studies show these particles accumulate in ovarian tissue, disrupt hormones, and cause oxidative stress, leading to hormonal imbalances and ovarian damage, though research in humans is still limited.
Reproductive toxicity and related mechanisms of micro(nano)plastics in terrestrial mammals: Review of current evidence.
This review of terrestrial mammal studies found that micro- and nanoplastics induce reproductive toxicity through oxidative stress, inflammation, endocrine disruption, and DNA damage, affecting both male and female fertility. In males, effects include blood-testis barrier disruption and impaired spermatogenesis, while females show compromised oocyte maturation, ovarian fibrosis, and diminished ovarian reserve, with particles also capable of crossing the maternal-fetal interface.
Plastic Particles and Female Fertility: Pathways, Toxicity, and Analytical Challenges
This review examines the pathways, toxicity mechanisms, and analytical challenges associated with microplastic and nanoplastic impacts on female fertility. Evidence from animal studies indicates that these particles can accumulate in ovaries and placental tissue, inducing oxidative stress, inflammation, and granulosa cell death that diminishes ovarian reserve. The study notes that microplastics have been confirmed in human placentas and umbilical cord blood, and may disrupt the hormonal axis governing reproduction.
"Unseen Dangers: The Effects of Micro- and Nanoplastics on Human Reproductive Health - A Narrative Review"
This review examines the effects of micro- and nanoplastics on human reproductive health, covering evidence from in vitro, animal, and epidemiological studies showing that plastic particles can disrupt hormone signaling, sperm function, ovarian development, and placental integrity.
Toxicological effects of micro/nano-plastics on human reproductive health: A review
This review summarizes research on how micro- and nanoplastics affect human reproductive health in both men and women. Evidence from animal and lab studies shows that these particles can accumulate in reproductive organs, disrupt hormones, damage eggs and sperm, and cause inflammation and oxidative stress. While human studies are still limited, the growing body of evidence suggests that microplastic exposure is a potential threat to fertility that warrants further investigation.
Effects of micro(nano)plastics on the reproductive system: A review
This review summarizes research on how micro and nanoplastics affect the reproductive system in both animal studies and cell experiments. Evidence indicates these particles can cross biological barriers, accumulate in reproductive organs, and disrupt hormones, egg development, and sperm quality. While human studies are still limited, the animal data suggests microplastic exposure may be a meaningful concern for reproductive health.
Impact of nanoparticles and nanoplastics on female reproductive health
This review examines the evidence on how nanoparticles and nanoplastics may affect female reproductive health after entering the body through dermal, oral, and inhalation routes. Researchers note that these materials have been found in human ovarian tissue, raising concern about their potential effects on fertility and reproductive outcomes. The study highlights the need for more research into the reproductive health implications of nanoplastic exposure.
Understanding the impact of nanoplastics on reproductive health: Exposure pathways, mechanisms, and implications
This review summarizes existing research on how nanoplastics (tiny plastic particles smaller than one micrometer) affect reproductive health in animals and potentially humans. Studies show that nanoplastics can accumulate in reproductive organs including the placenta, and evidence from animal studies links exposure to hormone disruption, reduced fertility, and developmental problems. The authors highlight a significant knowledge gap about nanoplastic effects on human reproduction, despite growing evidence that these particles reach our reproductive systems.
Effects of nano and microplastics on the reproduction system: In vitro and in vivo studies review
This review summarizes both lab and animal studies on how micro and nanoplastics affect the reproductive system in males and females. Evidence shows that microplastics can reduce sperm quality, damage ovaries, disrupt hormone levels, and even cross the placenta during pregnancy. The findings raise significant concerns about how widespread microplastic exposure might contribute to fertility problems and reproductive health issues in humans.
Toxicity of microplastics and nanoplastics: invisible killers of female fertility and offspring health
This review summarizes research on how microplastics and nanoplastics affect female fertility across multiple species, from reproductive failure to developmental problems in offspring. The tiny particles can infiltrate the body through food, air, and skin, accumulating in reproductive tissues where they disrupt hormones and damage eggs. While animal studies cannot be directly applied to humans, the consistent findings across species raise serious concerns about the potential impact of microplastic exposure on women's reproductive health.
Adverse effects of microplastics and nanoplastics on the reproductive system: A comprehensive review of fertility and potential harmful interactions
This review summarizes how microplastics and nanoplastics can harm both male and female reproductive systems by disrupting hormone signaling, damaging sperm and egg cells, and causing inflammation in reproductive tissues. Smaller nanoplastics are especially concerning because they can cross biological barriers more easily and reach the testes and ovaries. With global infertility rates rising, the authors highlight environmental plastic exposure as a factor that deserves more research attention.
Adverse health effects and mechanisms of microplastics on female reproductive system: a descriptive review
This review describes how microplastics, particularly polystyrene, can reach and accumulate in the female reproductive system through ingestion, inhalation, and skin contact. Animal studies suggest these particles may disrupt ovarian function, hormone balance, and fertility through oxidative stress and inflammation. While human evidence is still emerging, the research raises important questions about microplastic exposure and women's reproductive health.
Reproductive and developmental implications of micro- and nanoplastic internalization: Recent advances and perspectives
This systematic review documented the detection of micro- and nanoplastics in human semen, placenta, and ovarian follicular fluid, and found evidence linking exposure to impaired sperm quality, disrupted ovarian function, and adverse pregnancy outcomes. In animal models, MNPs caused developmental toxicity and transgenerational effects, with oxidative stress, inflammation, and epigenetic modification identified as key mechanisms.
Reproductive toxicity of micro- and nanoplastics
This review summarizes existing research on how micro- and nanoplastics harm reproduction across many species, from marine invertebrates to mammals. The particles can cause oxidative stress and hormone disruption, leading to reduced fertility, abnormal embryo development, and toxic effects that pass to offspring. The findings raise concerns that human reproductive health could be similarly affected given our increasing exposure to these particles.
Research Progress in Reproductive Toxicity of Micro- and Nanoplastics on Males and Its Mechanisms
This review summarized research on the reproductive toxicity of micro- and nanoplastics (MNPs) in males, finding that MNPs accumulate in reproductive organs and cause toxicity through oxidative stress, hormonal disruption, and DNA damage, with implications for both animal and human reproductive health.
Impact of microplastics on female reproductive health: insights from animal and human experimental studies: a systematic review
This systematic review of 15 experimental studies found that microplastic exposure significantly impairs ovarian function, decreases fertility rates, and disrupts hormone levels in female subjects. Several studies also reported negative effects on embryo development and offspring health, though study quality varied and more rigorous research is needed to confirm mechanisms.
Unraveling the threat: Microplastics and nano-plastics' impact on reproductive viability across ecosystems
This review summarizes research on how microplastics and nanoplastics affect reproduction across many species, from aquatic invertebrates to mammals including humans. In males, exposure leads to testicular damage, lower sperm quality, and hormone disruption; in females, it causes ovarian and uterine problems, inflammation, and reduced fertility. The evidence also shows these reproductive harms can be passed to offspring, raising serious concerns about long-term effects on human fertility.
Nano and microplastics: unveiling their profound impact on endocrine health
This review summarizes existing research showing that micro- and nanoplastics can disrupt the endocrine (hormone) system, altering reproductive hormones, thyroid function, and gene expression in lab and animal studies. Exposure to these particles triggered inflammation markers and oxidative stress in hormone-producing organs, suggesting that widespread plastic pollution may be contributing to rising rates of hormonal and reproductive health problems.
Microplastics and human fertility: A comprehensive review of their presence in human samples and reproductive implication
This review examines the growing evidence linking microplastic and nanoplastic exposure to potential effects on human fertility. Researchers noted that these tiny plastic particles have been detected in blood, placenta, and seminal fluid, suggesting continuous systemic exposure and the ability to cross key biological barriers. Animal studies indicate that microplastics may affect reproductive health through oxidative stress, hormonal disruption, and tissue damage, though more standardized human research is needed.
Exposure to micro- and nanoplastics and human reproductive outcomes: a systematic review
This systematic review summarizes existing research on whether micro and nanoplastics affect human fertility and pregnancy outcomes. While the evidence is still emerging, the review found that these particles have been detected in placenta and fetal tissue, raising important questions about potential effects on reproductive health that warrant further study.
The impact of microplastics on female reproduction and early life
This review examined the current evidence on how micro- and nanoplastics may affect female reproduction and early life development. Researchers found that studies in animals suggest microplastics can cross important biological barriers and may interfere with reproductive processes, though human data remains very limited. The study highlights the urgent need for standardized methods to measure human exposure and better understand potential reproductive health effects.
Micro- and Nanoplastics as Disruptors of the Endocrine System—A Review of the Threats and Consequences Associated with Plastic Exposure
This review summarizes how micro- and nanoplastics carry endocrine-disrupting chemicals that interfere with hormones controlling reproduction, thyroid function, metabolism, and brain development. The reproductive system is especially vulnerable, with studies showing that plastic particle exposure can cause oxidative stress, cell death, and infertility, raising serious concerns given how widespread these particles are in food and the environment.
The Pressing Issue of Micro- and Nanoplastic Contamination: Profiling the Reproductive Alterations Mediated by Oxidative Stress
This review examined how micro- and nanoplastics affect reproductive health across aquatic and land-based organisms, focusing on oxidative stress as the primary damage mechanism. Researchers found that these plastic particles can reach the gonads through the bloodstream and even accumulate in human and mouse placenta, with harmful effects on sperm and egg development, embryo growth, and offspring survival. The severity of reproductive harm appears to increase with smaller particle sizes and longer exposure times.
The reproductive and transgenerational toxicity of microplastics and nanoplastics: A threat to mammalian fertility in both sexes
This review examines how microplastics and nanoplastics can accumulate in reproductive organs and harm fertility in both males and females. In animal studies, exposure led to damaged sperm, disrupted hormones, and abnormal ovary and uterus structure. Offspring of exposed mothers also showed metabolic problems, immune issues, and cognitive disorders, suggesting these particles may affect future generations.