We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Research Progress in Reproductive Toxicity of Micro- and Nanoplastics on Males and Its Mechanisms
Summary
This review summarized research on the reproductive toxicity of micro- and nanoplastics (MNPs) in males, finding that MNPs accumulate in reproductive organs and cause toxicity through oxidative stress, hormonal disruption, and DNA damage, with implications for both animal and human reproductive health.
微纳米塑料是一种新型的环境污染物，不仅造成环境污染，对动物和人类健康也造成极大威胁。研究发现微纳米塑料在人和动物的生殖系统中积累，并产生毒性作用。本文主要介绍了微纳米塑料对雄性生殖毒性及其潜在的作用机制，为防控微纳米塑料引起的雄性生殖毒性提供理论基础，维护生殖健康。Micro- and Nanoplastics are a new type of environmental pollutant that not only cause environmental pollution, but also pose a great threat to animal and human health. Research has found that micro- and nanoplastics accumulate in the reproductive system of human and animals, and exhibit reproductive toxicity. This article mainly introduces the reproductive toxicity of micro- and nanoplastics on males and their potential mechanisms, providing a theoretical basis for preventing and controlling the reproductive toxicity caused by micro- and nanoplastics in males and maintaining reproductive health.
Sign in to start a discussion.
More Papers Like This
Reproductive toxicity and related mechanisms of micro(nano)plastics in terrestrial mammals: Review of current evidence.
This review of terrestrial mammal studies found that micro- and nanoplastics induce reproductive toxicity through oxidative stress, inflammation, endocrine disruption, and DNA damage, affecting both male and female fertility. In males, effects include blood-testis barrier disruption and impaired spermatogenesis, while females show compromised oocyte maturation, ovarian fibrosis, and diminished ovarian reserve, with particles also capable of crossing the maternal-fetal interface.
Toxicological effects of micro/nano-plastics on human reproductive health: A review
This review summarizes research on how micro- and nanoplastics affect human reproductive health in both men and women. Evidence from animal and lab studies shows that these particles can accumulate in reproductive organs, disrupt hormones, damage eggs and sperm, and cause inflammation and oxidative stress. While human studies are still limited, the growing body of evidence suggests that microplastic exposure is a potential threat to fertility that warrants further investigation.
Reproductive and developmental implications of micro- and nanoplastic internalization: Recent advances and perspectives
This systematic review documented the detection of micro- and nanoplastics in human semen, placenta, and ovarian follicular fluid, and found evidence linking exposure to impaired sperm quality, disrupted ovarian function, and adverse pregnancy outcomes. In animal models, MNPs caused developmental toxicity and transgenerational effects, with oxidative stress, inflammation, and epigenetic modification identified as key mechanisms.
Unravelling the potential mechanisms of nano- and microplastic toxicity to the male reproductive system: A systematic review
This systematic review found that micro- and nanoplastics accumulate in the testes and epididymis in rodent models, disrupting the blood-testis barrier, increasing germ cell death, reducing sperm motility, and causing hormone imbalance through oxidative stress and inflammation. Smaller nanoplastics penetrate tissues more readily for molecular disruption, while larger microplastics cause greater structural damage.
Reproductive toxicity of micro- and nanoplastics
This review summarizes existing research on how micro- and nanoplastics harm reproduction across many species, from marine invertebrates to mammals. The particles can cause oxidative stress and hormone disruption, leading to reduced fertility, abnormal embryo development, and toxic effects that pass to offspring. The findings raise concerns that human reproductive health could be similarly affected given our increasing exposure to these particles.