Papers

61,005 results
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Article Tier 2

Insights into the toxicological effects of nanomaterials on atherosclerosis: mechanisms involved and influence factors

Researchers reviewed how nanomaterials — tiny engineered particles including nanoplastics — can trigger or worsen atherosclerosis, the buildup of fatty plaques in arteries that leads to heart attacks and strokes. The review found that nanomaterials can damage the cells lining blood vessels and provoke chronic inflammation, raising concerns about the cardiovascular risks of widespread nanomaterial exposure.

2023 Journal of Nanobiotechnology 15 citations
Article Tier 2

Emerging Links Between Cardiovascular Disease and Microplastics Exposure – A Narrative Review

This review of existing research shows that tiny plastic particles called microplastics may be linked to heart disease - scientists have even found these particles inside the fatty buildups that clog arteries. When microplastics get into our bodies through food, water, and air, they appear to cause inflammation and damage blood vessels, which could increase the risk of heart attacks and strokes. People who eat lots of seafood, drink bottled water frequently, or work in certain industries may face higher exposure to these harmful plastic particles.

2026 Hellenic Journal of Cardiology
Article Tier 2

Evidence, Mechanisms, and Clinical Implications of Microplastics and Nanoplastics As Emerging Cardiovascular Risk Factors: A Narrative Review

This review examines growing evidence that micro- and nanoplastics may contribute to cardiovascular health risks, with researchers having found these particles in human artery plaques and blood clots. Evidence indicates that the particles can enter the bloodstream, trigger inflammation, damage blood vessel walls, and potentially increase the risk of heart attacks and strokes. While the evidence is not yet conclusive, the study highlights an emerging area of concern that warrants further investigation into how everyday plastic exposure may affect heart and blood vessel health.

2025 Cureus 2 citations
Article Tier 2

Microplastics. a New Risk Factor for Atherosclerotic Cardiovascular Disease

This paper reviews emerging evidence linking microplastic exposure to atherosclerotic cardiovascular disease, noting that MPs have been detected in arterial plaques and human tissues and may contribute to cardiovascular risk through inflammation, oxidative stress, and endothelial disruption.

2025 American Journal of Preventive Cardiology
Systematic Review Tier 1

Micro- and nanoplastics in the cardiovascular system: current evidence, research gaps: a systematic review

This systematic review examined how microplastics and nanoplastics affect the heart and blood vessels. Studies in both animals and human tissue found that these particles can cause blood vessel inflammation, disrupt heart function, and were even linked to higher rates of heart attack and stroke in people with plastic particles in their arteries.

2025 MEDICAL SCIENCE PULSE
Article Tier 2

Microplastics, Nanoplastics and Heart Contamination: The Hidden Threat

This review examines growing evidence that micro- and nanoplastics can accumulate in human cardiovascular tissues, including blood, heart muscle, and arterial plaques. Researchers found that these particles may contribute to heart and blood vessel problems through inflammation, oxidative stress, blood clotting, and direct tissue injury. The study identifies plastic particles as a potential new environmental risk factor for cardiovascular health.

2025 Journal of Clinical Medicine 2 citations
Article Tier 2

Emerging cardiovascular risks of micro- and nanoplastics: toxic effects and mechanistic pathways

Tiny plastic particles called micro- and nanoplastics are getting into our bodies through food, air, and skin contact, and researchers have found them building up in people's hearts and blood vessels. This review of existing studies shows these plastic bits may contribute to heart disease by causing inflammation and damaging cells in the cardiovascular system. While more research is needed, this suggests that plastic pollution isn't just an environmental problem—it could be directly harming our heart health.

2026 Particle and Fibre Toxicology
Article Tier 2

Micro and Nano-plastic particles: What are they and do they effect cardiovascular health?

This review examines the cardiovascular health effects of micro- and nanoplastics, summarizing evidence that these particles have been detected in human tissues including arterial plaques and may promote endothelial dysfunction and inflammation. The authors call for further clinical and epidemiological research into cardiac risk.

2024 Nepal Journal of Epidemiology 1 citations
Article Tier 2

An Emerging Role of Micro- and Nanoplastics in Vascular Diseases

This review summarizes emerging research on how micro- and nanoplastics may contribute to vascular diseases, which are the leading cause of death worldwide. Studies suggest that these tiny plastic particles can damage blood vessel walls, promote inflammation, and worsen conditions like atherosclerosis. While more research is needed, the evidence points to microplastic exposure as a potential new risk factor for heart and blood vessel diseases.

2024 Life 15 citations
Article Tier 2

Atherosclerosis and the Bidirectional Relationship between Cancer and Cardiovascular Disease: From Bench to Bedside—Part 1

This review explores the two-way relationship between cancer and cardiovascular disease, focusing on how atherosclerosis (artery-clogging plaque buildup) connects the two conditions through shared risk factors like chronic inflammation. While not directly focused on microplastics, the inflammatory pathways described are relevant because emerging research suggests microplastic exposure may contribute to cardiovascular inflammation, potentially adding to the disease burden discussed in this review.

2024 International Journal of Molecular Sciences 20 citations
Article Tier 2

Micro-nanoplastics and cardiovascular diseases: evidence and perspectives

Growing evidence suggests that micro- and nanoplastic particles may be a previously unrecognized risk factor for heart disease, as they have been detected in atherosclerotic plaques, heart tissue, and blood clots in humans. Lab studies show these particles can trigger oxidative stress, promote blood clotting, and cause inflammation in blood vessel cells, and their presence in artery plaques has been linked to higher rates of cardiovascular events.

2024 European Heart Journal 88 citations
Article Tier 2

Impact of microplastics and nanoplastics on cardiovascular health

This review examines the emerging evidence on how microplastics and nanoplastics may affect cardiovascular health. The study discusses clinical evidence suggesting that these particles can accumulate in the cardiovascular system and highlights possible molecular mechanisms including inflammation and oxidative stress, while noting that current evidence linking microplastics to cardiovascular disease remains largely correlative.

2026 Trends in Cardiovascular Medicine
Article Tier 2

Micro- and nanoplastics: A new cardiovascular risk factor?

This review examines the growing evidence that micro- and nanoplastics may pose risks to the heart and blood vessels. Studies in animals and cell cultures show that these tiny plastic particles can enter the bloodstream, trigger inflammation, promote blood clotting, and damage blood vessel walls. While human data is still limited, the review suggests that micro- and nanoplastic exposure should be considered a potential new risk factor for cardiovascular disease.

2022 Environment International 227 citations
Article Tier 2

Microplastics and nanoplastics in cardiovascular disease—a narrative review with worrying links

This review summarizes growing evidence linking micro- and nanoplastic exposure to cardiovascular disease, including increased blood pressure, blood vessel inflammation, and heart muscle damage observed in animal studies. Human population studies also show that people exposed to more plastics face higher rates of hypertension and heart attacks, though researchers are still working to understand the exact biological mechanisms involved.

2024 Frontiers in Toxicology 35 citations
Article Tier 2

Microplastics and Nanoplastics in Atheromas and Cardiovascular Events

This landmark clinical study found that patients with micro- and nanoplastics detected in their carotid artery plaque had a significantly higher risk of heart attack, stroke, or death over a 34-month follow-up period compared to those without detectable plastics. This is one of the first studies to directly link microplastic presence in human blood vessels to worse cardiovascular outcomes. The findings suggest that plastic accumulation in arteries may be an important and previously unrecognized risk factor for heart disease.

2024 New England Journal of Medicine 843 citations
Article Tier 2

Microplastics and nanoplastics: emerging threats to cardiovascular health – a comprehensive review

This comprehensive review examines the emerging evidence linking microplastic and nanoplastic exposure to cardiovascular health problems. The evidence suggests that plastic particles may contribute to heart and blood vessel disease, though more research is needed to fully understand the long-term effects. The review highlights the urgent need for further studies on how chronic exposure to these tiny particles affects the cardiovascular system.

2024 Annals of Medicine and Surgery 13 citations
Article Tier 2

Microplastics: A Modifiable Cardiac Risk Factor

This review examines the emerging evidence linking microplastic exposure to cardiovascular disease risk factors, including oxidative stress, inflammation, endothelial dysfunction, and thrombosis. The study highlights that micro- and nanoplastics have been identified in coronary artery plaque, suggesting that microplastic exposure may represent a modifiable but currently underrecognized cardiac risk factor.

2026 Cardiology in Review
Article Tier 2

Micro-nanoplastic induced cardiovascular disease and dysfunction: a scoping review

Researchers reviewed evidence from animal and human studies on how micro- and nanoplastics (MNPs) affect the heart and blood vessels, finding that MNPs can damage the inner lining of blood vessels, promote plaque buildup, and interfere with blood clotting — all of which raise the risk of heart disease. The review calls for more research to understand how much MNP accumulation occurs in the human cardiovascular system and what it means for long-term cardiac health.

2025 Journal of Exposure Science & Environmental Epidemiology 16 citations
Article Tier 2

From Environment to Endothelium: The Role of Microplastics in Vascular Aging

This review examines how microplastics may contribute to vascular aging and cardiovascular problems. Evidence indicates that once microplastics enter the body through ingestion, inhalation, or skin contact, they can reach blood vessels and trigger oxidative stress, inflammation, and damage to the cells lining blood vessel walls. The findings suggest that chronic microplastic exposure could be an underappreciated factor in the development of age-related cardiovascular issues.

2025 Microplastics 4 citations
Article Tier 2

Plastic particle impacts on the cardiovascular system and angiogenesis potential

This review examines emerging evidence on how micro- and nanoplastic particles may affect the cardiovascular system. Researchers found that these particles can potentially cross biological barriers and reach cardiovascular tissues, where they may interact with cellular components and amplify the toxicity of other co-occurring contaminants.

2024 Molecular and Cellular Biochemistry 3 citations
Systematic Review Tier 1

Micro- and Nanoplastics as a Potential Risk Factor for Stroke: A Systematic Review

This systematic review assessed the potential link between micro- and nanoplastics and stroke risk. It found that plastic particles have been detected in human blood vessels and arterial plaques, and may contribute to inflammation and blood vessel damage — factors that could increase the risk of stroke.

2026 Journal of Xenobiotics
Systematic Review Tier 1

Impacts of micro- and nanoplastic exposure on the cardiovascular system: a systematic review focused on in vivo studies

This systematic review summarizes 38 animal studies on how micro- and nanoplastics affect the heart and blood vessels. The research found that these tiny plastic particles can deposit in cardiovascular tissue, trigger inflammation and oxidative stress, and cause structural damage, raising concerns about potential heart health risks from ongoing plastic exposure.

2024 All Life 6 citations
Article Tier 2

Nanoplastics as emerging cardiovascular hazards: a narrative review of current evidence

This review examines the emerging evidence that nanoplastics may pose risks to cardiovascular health. Researchers summarized studies showing that nanoplastics can enter the bloodstream through ingestion, inhalation, and skin contact, potentially causing inflammation and oxidative damage to blood vessels and heart tissue. The study suggests that nanoplastic exposure represents an understudied but potentially significant environmental risk factor for heart and vascular problems.

2024 The Egyptian Journal of Internal Medicine 7 citations
Article Tier 2

Environmental microplastic and nanoplastic: Exposure routes and effects on coagulation and the cardiovascular system

This review explores how environmental microplastic and nanoplastic particles may affect blood coagulation and the cardiovascular system in humans. Researchers summarized evidence suggesting that plastic particles can enter the body through ingestion, inhalation, and skin contact, potentially triggering inflammatory responses in blood vessels. The study highlights the need for more research on how chronic exposure to these tiny plastic particles may contribute to cardiovascular health risks.

2021 Environmental Pollution 168 citations