Papers

61,005 results
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Systematic Review Tier 1

Micro- and nanoplastics in the cardiovascular system: current evidence, research gaps: a systematic review

This systematic review examined how microplastics and nanoplastics affect the heart and blood vessels. Studies in both animals and human tissue found that these particles can cause blood vessel inflammation, disrupt heart function, and were even linked to higher rates of heart attack and stroke in people with plastic particles in their arteries.

2025 MEDICAL SCIENCE PULSE
Article Tier 2

Micro-nanoplastics and cardiovascular diseases: evidence and perspectives

Growing evidence suggests that micro- and nanoplastic particles may be a previously unrecognized risk factor for heart disease, as they have been detected in atherosclerotic plaques, heart tissue, and blood clots in humans. Lab studies show these particles can trigger oxidative stress, promote blood clotting, and cause inflammation in blood vessel cells, and their presence in artery plaques has been linked to higher rates of cardiovascular events.

2024 European Heart Journal 88 citations
Article Tier 2

Micro- and nanoplastics: A new cardiovascular risk factor?

This review examines the growing evidence that micro- and nanoplastics may pose risks to the heart and blood vessels. Studies in animals and cell cultures show that these tiny plastic particles can enter the bloodstream, trigger inflammation, promote blood clotting, and damage blood vessel walls. While human data is still limited, the review suggests that micro- and nanoplastic exposure should be considered a potential new risk factor for cardiovascular disease.

2022 Environment International 227 citations
Article Tier 2

Emerging cardiovascular risks of micro- and nanoplastics: toxic effects and mechanistic pathways

Tiny plastic particles called micro- and nanoplastics are getting into our bodies through food, air, and skin contact, and researchers have found them building up in people's hearts and blood vessels. This review of existing studies shows these plastic bits may contribute to heart disease by causing inflammation and damaging cells in the cardiovascular system. While more research is needed, this suggests that plastic pollution isn't just an environmental problem—it could be directly harming our heart health.

2026 Particle and Fibre Toxicology
Article Tier 2

Micro-nanoplastic induced cardiovascular disease and dysfunction: a scoping review

This scoping review examined evidence linking micro- and nanoplastic exposure to cardiovascular disease and dysfunction, summarizing findings from animal and in vitro studies and identifying plausible mechanisms including inflammation and oxidative stress.

2024
Article Tier 2

Microplastics, Nanoplastics and Heart Contamination: The Hidden Threat

This review examines growing evidence that micro- and nanoplastics can accumulate in human cardiovascular tissues, including blood, heart muscle, and arterial plaques. Researchers found that these particles may contribute to heart and blood vessel problems through inflammation, oxidative stress, blood clotting, and direct tissue injury. The study identifies plastic particles as a potential new environmental risk factor for cardiovascular health.

2025 Journal of Clinical Medicine 2 citations
Systematic Review Tier 1

Impacts of micro- and nanoplastic exposure on the cardiovascular system: a systematic review focused on in vivo studies

This systematic review summarizes 38 animal studies on how micro- and nanoplastics affect the heart and blood vessels. The research found that these tiny plastic particles can deposit in cardiovascular tissue, trigger inflammation and oxidative stress, and cause structural damage, raising concerns about potential heart health risks from ongoing plastic exposure.

2024 All Life 6 citations
Article Tier 2

Tiny trouble: microplastics, nanoplastics, and their heartfelt impact on cardiovascular health

This review summarizes growing evidence that microplastics and nanoplastics have been found in human heart tissue, arterial plaques, and blood, and may increase the risk of cardiovascular disease. Lab studies show these particles can damage blood vessel walls, disrupt cholesterol processing, trigger inflammation, and promote blood clot formation, raising serious concerns about heart health.

2025 Cardiovascular Research 10 citations
Article Tier 2

Microplastics and nanoplastics: emerging threats to cardiovascular health – a comprehensive review

This comprehensive review examines the emerging evidence linking microplastic and nanoplastic exposure to cardiovascular health problems. The evidence suggests that plastic particles may contribute to heart and blood vessel disease, though more research is needed to fully understand the long-term effects. The review highlights the urgent need for further studies on how chronic exposure to these tiny particles affects the cardiovascular system.

2024 Annals of Medicine and Surgery 13 citations
Article Tier 2

Micro and Nano-plastic particles: What are they and do they effect cardiovascular health?

This review examines the cardiovascular health effects of micro- and nanoplastics, summarizing evidence that these particles have been detected in human tissues including arterial plaques and may promote endothelial dysfunction and inflammation. The authors call for further clinical and epidemiological research into cardiac risk.

2024 Nepal Journal of Epidemiology 1 citations
Article Tier 2

Micro/nano-plastics impacts in cardiovascular systems across species

This review summarizes research across multiple species showing that microplastics and nanoplastics can damage the cardiovascular system, causing blood clots, blood vessel injury, and heart problems in lab animals. Since these tiny particles have been found in human blood and can travel throughout the body, the findings raise serious concerns about the long-term heart health effects of microplastic exposure in people.

2024 The Science of The Total Environment 42 citations
Systematic Review Tier 1

From pollution to palpitations: the heart’s silent battle with microplastics

This systematic review examined 72 studies on how microplastics and nanoplastics affect the heart and blood vessels. The research found that these particles can impair heart function, cause tissue scarring, and trigger inflammation through oxidative stress. Smaller particles under 100 nanometers are especially concerning because they can penetrate deeper into the body, raising questions about the cardiovascular risks of long-term plastic particle exposure.

2025 BMC Cardiovascular Disorders 2 citations
Article Tier 2

Impact of microplastics and nanoplastics on cardiovascular health

This review examines the emerging evidence on how microplastics and nanoplastics may affect cardiovascular health. The study discusses clinical evidence suggesting that these particles can accumulate in the cardiovascular system and highlights possible molecular mechanisms including inflammation and oxidative stress, while noting that current evidence linking microplastics to cardiovascular disease remains largely correlative.

2026 Trends in Cardiovascular Medicine
Article Tier 2

Evidence, Mechanisms, and Clinical Implications of Microplastics and Nanoplastics As Emerging Cardiovascular Risk Factors: A Narrative Review

This review examines growing evidence that micro- and nanoplastics may contribute to cardiovascular health risks, with researchers having found these particles in human artery plaques and blood clots. Evidence indicates that the particles can enter the bloodstream, trigger inflammation, damage blood vessel walls, and potentially increase the risk of heart attacks and strokes. While the evidence is not yet conclusive, the study highlights an emerging area of concern that warrants further investigation into how everyday plastic exposure may affect heart and blood vessel health.

2025 Cureus 2 citations
Article Tier 2

Microplastics and nanoplastics in cardiovascular disease—a narrative review with worrying links

This review summarizes growing evidence linking micro- and nanoplastic exposure to cardiovascular disease, including increased blood pressure, blood vessel inflammation, and heart muscle damage observed in animal studies. Human population studies also show that people exposed to more plastics face higher rates of hypertension and heart attacks, though researchers are still working to understand the exact biological mechanisms involved.

2024 Frontiers in Toxicology 35 citations
Article Tier 2

Nanoplastics as emerging cardiovascular hazards: a narrative review of current evidence

This review examines the emerging evidence that nanoplastics may pose risks to cardiovascular health. Researchers summarized studies showing that nanoplastics can enter the bloodstream through ingestion, inhalation, and skin contact, potentially causing inflammation and oxidative damage to blood vessels and heart tissue. The study suggests that nanoplastic exposure represents an understudied but potentially significant environmental risk factor for heart and vascular problems.

2024 The Egyptian Journal of Internal Medicine 7 citations
Article Tier 2

Progress in Research on Microplastics and Nano-plastics Cardiac Toxicity

This review covers experimental and clinical evidence on the cardiovascular toxicity of microplastics and nanoplastics, documenting effects on heart function, vascular integrity, and inflammation pathways. It calls for more human clinical data to clarify the dose-response relationship and the relevance of laboratory findings to real-world cardiac risk.

2025 Advances in Life Science for Adolescents
Article Tier 2

Microplastics and Nanoplastics

Researchers examined the connection between microplastics and nanoplastics and cardiovascular disease, a group of conditions affecting the heart and blood vessels. Growing evidence suggests these tiny plastic particles may pose risks to heart and vascular health.

2024 JACC Advances 3 citations
Article Tier 2

Microplastics: A Matter of the Heart (and Vascular System)

This review summarizes growing evidence that microplastics and nanoplastics can damage the heart and blood vessel system in both fish and mammals. In fish, plastic particles enter through the gills and trigger inflammation, disrupt blood chemistry, promote blood clots, and cause heart damage. In mammals, including humans, microplastics interact with blood cells and proteins, travel to the heart, and cause oxidative stress in heart muscle cells, raising concerns about long-term cardiovascular health effects.

2023 Biomedicines 93 citations
Article Tier 2

Cardiotoxicity of Microplastics: An Emerging Cardiovascular Risk Factor

This review examines emerging evidence that microplastics may pose risks to cardiovascular health, summarizing findings from laboratory and animal studies. Researchers found that microplastic exposure has been linked to inflammation, oxidative stress, and disrupted heart function in experimental settings. Given that cardiovascular disease is already the leading cause of death globally, the study suggests that microplastics as a potential contributing factor warrant urgent further investigation.

2025 Current Cardiology Reviews 3 citations
Article Tier 2

An Emerging Role of Micro- and Nanoplastics in Vascular Diseases

This review summarizes emerging research on how micro- and nanoplastics may contribute to vascular diseases, which are the leading cause of death worldwide. Studies suggest that these tiny plastic particles can damage blood vessel walls, promote inflammation, and worsen conditions like atherosclerosis. While more research is needed, the evidence points to microplastic exposure as a potential new risk factor for heart and blood vessel diseases.

2024 Life 15 citations
Article Tier 2

Emerging Links Between Cardiovascular Disease and Microplastics Exposure – A Narrative Review

This review of existing research shows that tiny plastic particles called microplastics may be linked to heart disease - scientists have even found these particles inside the fatty buildups that clog arteries. When microplastics get into our bodies through food, water, and air, they appear to cause inflammation and damage blood vessels, which could increase the risk of heart attacks and strokes. People who eat lots of seafood, drink bottled water frequently, or work in certain industries may face higher exposure to these harmful plastic particles.

2026 Hellenic Journal of Cardiology
Article Tier 2

Microplastics and Cardiovascular Disease: Should Clinicians Be Paying Attention?

This clinical review summarizes evidence for microplastics as a cardiovascular risk factor, noting that they have been detected in human cardiovascular tissues and that in vitro and animal studies link them to oxidative stress, endothelial dysfunction, and platelet disruption, while cautioning that human evidence remains associative.

2025 Current Cardiology Reports
Article Tier 2

Micro- and nanoplastics and PM2.5 in cardiovascular disease: Emerging mechanisms, impacts, and therapeutic insights

This review synthesizes evidence linking micro- and nanoplastic exposure alongside fine particulate matter (PM2.5) to cardiovascular health risks, including endothelial dysfunction, atherosclerosis, and heart injury. Researchers found that these pollutants share common harmful mechanisms such as oxidative stress, mitochondrial dysfunction, and inflammatory reprogramming, suggesting they may act as underrecognized environmental risk factors for heart and vascular conditions.

2026 Food and Chemical Toxicology